-
公开(公告)号：US20180140613A1
公开(公告)日：2018-05-24
申请号：US15884484
申请日：2018-01-31
发明人： Paul Donnelly , James Hilton , Peter Crouch
IPC分类号： A61K31/555 , C07F3/06 , C07F1/08 , A61K31/145 , A61K31/30 , A61K31/28 , A61K31/315
CPC分类号： A61K31/555 , A61K31/145 , A61K31/28 , A61K31/30 , A61K31/315 , C07F1/08 , C07F3/06
摘要： The present invention relates to metal complexes, processes for their preparation and their use as pharmaceutical or veterinary agents, in particular for the treatment of conditions in which metal delivery can prevent, alleviate or ameliorate the condition. There are a number of clinical conditions which are caused by or associated with abnormal levels of metals (typically low metal levels). Conditions in of this type include cancer and conditions characterised by or associated with oxidative damage, more specifically neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease or Huntington's disease. The invention also relates to ligands useful in the preparation of metal complexes of this type.
-
公开(公告)号：US11123350B2
公开(公告)日：2021-09-21
申请号：US16433030
申请日：2019-06-06
发明人： Paul Donnelly , James Hilton , Peter Crouch
IPC分类号： A61K31/555 , C07F3/06 , C07F1/08 , A61K31/315 , A61K31/30 , A61K31/28 , A61K31/145
摘要： The present invention relates to metal complexes, processes for their preparation and their use as pharmaceutical or veterinary agents, in particular for the treatment of conditions in which metal delivery can prevent, alleviate or ameliorate the condition. There are a number of clinical conditions which are caused by or associated with abnormal levels of metals (typically low metal levels). Conditions in of this type include cancer and conditions characterised by or associated with oxidative damage, more specifically neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease or Huntington's disease. The invention also relates to ligands useful in the preparation of metal complexes of this type.
-
公开(公告)号：US20190298734A1
公开(公告)日：2019-10-03
申请号：US16433030
申请日：2019-06-06
发明人： Paul Donnelly , James Hilton , Peter Crouch
IPC分类号： A61K31/555 , A61K31/145 , A61K31/28 , C07F3/06 , A61K31/315 , C07F1/08 , A61K31/30
摘要： The present invention relates to metal complexes, processes for their preparation and their use as pharmaceutical or veterinary agents, in particular for the treatment of conditions in which metal delivery can prevent, alleviate or ameliorate the condition. There are a number of clinical conditions which are caused by or associated with abnormal levels of metals (typically low metal levels). Conditions in of this type include cancer and conditions characterised by or associated with oxidative damage, more specifically neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease or Huntington's disease. The invention also relates to ligands useful in the preparation of metal complexes of this type.
-
公开(公告)号：US10413554B2
公开(公告)日：2019-09-17
申请号：US15884484
申请日：2018-01-31
发明人： Paul Donnelly , James Hilton , Peter Crouch
IPC分类号： A61K31/555 , C07F3/06 , C07F1/08 , A61K31/315 , A61K31/30 , A61K31/28 , A61K31/145
摘要： The present invention relates to metal complexes, processes for their preparation and their use as pharmaceutical or veterinary agents, in particular for the treatment of conditions in which metal delivery can prevent, alleviate or ameliorate the condition. There are a number of clinical conditions which are caused by or associated with abnormal levels of metals (typically low metal levels). Conditions in of this type include cancer and conditions characterized by or associated with oxidative damage, more specifically neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease or Huntington's disease. The invention also relates to ligands useful in the preparation of metal complexes of this type.
-
-
-
搜索结果
4 条记录 (耗时 0.018 秒)