利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

43 条记录 (耗时 0.05 秒)

    Manufacturing method
    2.
    发明授权
    Manufacturing method 有权
    制造方法

    公开(公告)号：US06455726B2

    公开(公告)日：2002-09-24

    申请号：US09782291

    申请日：2001-02-14

    申请人： Masaharu Ichihara ,  Norio Hashimoto ,  Atsushi Kanda ,  Kooji Kagara

    发明人： Masaharu Ichihara ,  Norio Hashimoto ,  Atsushi Kanda ,  Kooji Kagara

    IPC分类号： C07C22900

    CPC分类号： C07C227/06 ,  C07C229/38 ,  C07C229/34

    摘要： A compound of the following formula (II) and a process for preparing of the compound of the following formula (I) its preparation wherein R1 is carboxy or protected carboxy; R2 is lower alkoxy or higher alkoxy; A1 is a divalent aromatic ring, a divalent heterocyclic group or a divalent cyclo(lower)alkane; and A2 is a divalent aromatic ring, a divalent heterocyclic group or a divalent cyclo(lower)alkane, or a salt thereof. The process comprises, reacting a compound of the formula (III): wherein R1, R2, A1 and A2 are each as defined above or a salt thereof, with an acid ammonium salt to give a compound of the formula (II).

    摘要翻译： 下式（II）的化合物及其制备方法，其中R1为羧基或被保护的羧基; R2为低级烷氧基或高级烷氧基; A1为二价芳环，二价杂环 基团或二价环（低级）烷烃; 和A 2是二价芳环，二价杂环基或二价环（低级）烷烃或其盐。 该方法包括使式（III）化合物：其中R1，R2，A1和A2各自如上定义，或其盐与酸性铵盐反应，得到式（II）化合物。

    Production process
    3.
    发明授权
    Production process 有权
    生产过程

    公开(公告)号：US06291680B1

    公开(公告)日：2001-09-18

    申请号：US09446359

    申请日：1999-12-20

    申请人： Masaharu Ichihara ,  Norio Hashimoto ,  Atsushi Kanda ,  Kooji Kagara

    发明人： Masaharu Ichihara ,  Norio Hashimoto ,  Atsushi Kanda ,  Kooji Kagara

    IPC分类号： C07D261106

    CPC分类号： C07C227/06 ,  C07C229/38 ,  C07C229/34

    摘要： A compound of formula (1) or a salt thereof: wherein R1 is a carboxy or a protected carboxy; R2 is a lower alkoxy or a higher alkoxy; A1 is a divalent aromatic ring, a divalent heterocyclic group or a divalent cyclo(lower)alkane; and A2 a divalent aromatic ring, a divalent heterocyclic group or a divalent cyclo(lower)alkane; is prepared by reacting a compound of formula (III) or a salt thereof with acid ammonium salt: wherein R1, R2, A1 and A2 are each as defined above; to give a compound of formula (II) or a salt thereof which is further reacted with a salt of hydroxylamine: wherein R1, R2, A1 and A2 are each as defined above.

    摘要翻译： 式（1）的化合物或其盐：其中R1是羧基或被保护的羧基; R2是低级烷氧基或高级烷氧基; A1是二价芳环，二价杂环基或二价环（低级）烷烃; 和A2为二价芳环，二价杂环基或二价环（低级）烷烃; 通过使式（III）的化合物或其盐与酸性铵盐反应制备：其中R1，R2，A1和A2各自如上所定义; 得到与羟胺盐进一步反应的式（II）化合物或其盐：其中R1，R2，A1和A2各自如上所定义。

    Process for producing aminopiperazine derivatives
    4.
    发明授权
    Process for producing aminopiperazine derivatives 失效
    制备氨基哌嗪衍生物的方法

    公开(公告)号：US06355800B1

    公开(公告)日：2002-03-12

    申请号：US09509812

    申请日：2000-04-06

    申请人： Kooji Kagara ,  Norio Hashimoto ,  Atsushi Kanda ,  Yukihisa Baba ,  Tetsuo Furutera

    发明人： Kooji Kagara ,  Norio Hashimoto ,  Atsushi Kanda ,  Yukihisa Baba ,  Tetsuo Furutera

    IPC分类号： C07D29532

    CPC分类号： C07D295/32

    摘要： A new industrial process excellent in yield and purity for preparing a compound of the formula: or a salt thereof in a less number of steps with a synthetic pathway without proceeding via nitroso compounds, wherein R1 is lower aryl, ar(lower)alkoxy or heterocyclic group, each of which may be substituted with halogen, and R2 is cyclo(lower)alkyl, aryl or ar(lower)alkyl, each of which may be substituted with halogen.

    摘要翻译： 一种新的工业方法，其具有优良的产率和纯度，用于通过合成途径制备下式化合物或其盐在较少数量的步骤中，而不经由亚硝基化合物进行，其中R 1为低级芳基，芳（低级）烷氧基或杂环 基团，其各自可以被卤素取代，并且R 2是环（低级）烷基，芳基或芳（低级）烷基，其各自可以被卤素取代。

    Benzopyran compound
    7.
    发明授权
    Benzopyran compound 有权
    苯并吡喃化合物

    公开(公告)号：US07781483B2

    公开(公告)日：2010-08-24

    申请号：US10590207

    申请日：2005-02-25

    申请人： Toru Tsukagoshi ,  Takayuki Nagatsuka ,  Tomoyuki Matsuda ,  Norio Hashimoto

    发明人： Toru Tsukagoshi ,  Takayuki Nagatsuka ,  Tomoyuki Matsuda ,  Norio Hashimoto

    IPC分类号： A61K31/353 ,  C07D311/68 ,  C07D311/70

    CPC分类号： C07D311/68 ,  C07D311/72

    摘要： This invention relates to benzopyran compounds of formula (I) wherein X is NR6, Y is a bond, SO or SO2, Z is C1-4alkyl group or phenyl group, W is hydrogen atom, hydroxy group, C1-6 alkoxy group, a halogen atom, C1-4alkyl group or C1-6alkylsulfonylamino group, R1 and R2 are independently of each other C1-3alkyl group, R3 is hydrogen atom, hydroxy group or methoxy group, m is an integer of 0 to 4, n is an integer of 0 to 4, V is a single bond, CR7R8, NR9, O, S, SO or SO2, R4 is hydrogen atom or C1-6alkyl group, R5 is hydrogen atom, C1-6alkyl group, C3-8cycloalkyl group, C3-8cycloalkenyl group, C6-14aryl group or C2-9heteroaryl group. These compounds are useful as an anti-arrhythmic agent.

    摘要翻译： 本发明涉及式（I）的苯并吡喃化合物，其中X为NR6，Y为键，SO或SO2，Z为C1-4烷基或苯基，W为氢原子，羟基，C1-6烷氧基， 卤素原子，C 1-4烷基或C 1-6烷基磺酰基氨基，R 1和R 2彼此独立地为C 1-3烷基，R 3为氢原子，羟基或甲氧基，m为0〜4的整数，n为整数 0〜4，V为单键，CR7R8，NR9，O，S，SO或SO2，R4为氢原子或C1-6烷基，R5为氢原子，C1-6烷基，C3-8环烷基，C3- 8环烯基，C6-14芳基或C2-9杂芳基。 这些化合物可用作抗心律不齐剂。

    IMAGE HEATING APPARATUS AND PRESSURE ROLLER THEREIN
    10.
    发明申请
    IMAGE HEATING APPARATUS AND PRESSURE ROLLER THEREIN 有权
    图像加热装置和压力滚子

    公开(公告)号：US20090116886A1

    公开(公告)日：2009-05-07

    申请号：US12259755

    申请日：2008-10-28

    申请人： Hiroaki Sakai ,  Norio Hashimoto ,  Yuko Sekihara ,  Kazuo Kishino ,  Masaaki Takahashi ,  Katsuhisa Matsunaka ,  Atsushi Iwasaki ,  Hiroyuki Sakakibara

    发明人： Hiroaki Sakai ,  Norio Hashimoto ,  Yuko Sekihara ,  Kazuo Kishino ,  Masaaki Takahashi ,  Katsuhisa Matsunaka ,  Atsushi Iwasaki ,  Hiroyuki Sakakibara

    IPC分类号： G03G15/20

    CPC分类号： G03G15/2053

    摘要： A pressure member contacts with a heating member 23 to form a nip part N where a recording material P is heated and pinched-conveyed, and includes a first elastic layer 24a and a second elastic layer 24b having higher thermal conductivity than that of the first elastic layer. An elastic layer is formed in combination of the first elastic layer and the second elastic layer so that the thickness of the second elastic layer at the end portion is thicker than the thickness of the second elastic layer at the center portion in a longitudinal direction perpendicular to a recording material conveyance direction. Accordingly, in the pressure member contacting with the heating member to form the nip part, it is possible to reduce a difference between a center nip width and an end-portion nip width of the nip part.

    摘要翻译： 压力构件与加热构件23接触以形成夹持部分N，其中记录材料P被加热和夹持输送，并且包括第一弹性层24a和具有比第一弹性体的导热性更高的导热性的第二弹性层24b 层。 第一弹性层和第二弹性层组合形成弹性层，使得端部的第二弹性层的厚度比垂直于第一弹性层的纵向方向中心部分的第二弹性层的厚度厚 记录材料输送方向。 因此，在与加热部件接触的压力部件中形成夹持部的情况下，能够减小夹持部的中心夹持宽度与端部夹持宽度的差。