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    Process for producing crystalline nucleus and method of screening crystallization conditions
    2.
    发明授权
    Process for producing crystalline nucleus and method of screening crystallization conditions 失效
    生产晶核的方法和筛选结晶条件的方法

    公开(公告)号：US07247203B2

    公开(公告)日：2007-07-24

    申请号：US10525809

    申请日：2003-08-25

    申请人： Takatomo Sasaki ,  Yusuke Mori ,  Masashi Yoshimura ,  Hiroaki Adachi ,  Hiroshi Masuhara ,  Youichiroh Hosokawa ,  Kazufumi Takano

    发明人： Takatomo Sasaki ,  Yusuke Mori ,  Masashi Yoshimura ,  Hiroaki Adachi ,  Hiroshi Masuhara ,  Youichiroh Hosokawa ,  Kazufumi Takano

    IPC分类号： C30B29/54

    CPC分类号： C30B7/00 ,  C30B29/58 ,  Y10S117/904

    摘要： The present invention relates to a process for producing high-quality crystals of protein or organic substances easily and efficiently. A solution of protein or an organic substance is prepared and then is cooled slowly to be supersaturated to a low degree. This supersaturated solution is irradiated with a femtosecond laser 10. A local explosion phenomenon occurs at the focal point of the laser and thereby a crystalline nucleus is generated. A high-quality crystal is obtained when a crystal is grown on the crystalline nucleus over a long period of time. The femtosecond laser to be used herein can be a titanium:sapphire laser having a wavelength of 800 nm, a duration of 120 fs, a frequency of 1 kHz, and an output of 400 mW.

    摘要翻译： 本发明涉及容易高效地生产蛋白质或有机物质的优质晶体的方法。 制备蛋白质或有机物质的溶液，然后缓慢冷却至低饱和度。 用飞秒激光10照射该过饱和溶液。 在激光的焦点发生局部爆炸现象，从而产生晶核。 当晶体长时间在晶核上生长时，获得高质量的晶体。 本文使用的飞秒激光可以是波长为800nm，持续时间为120fs，频率为1kHz，输出为400mW的钛：蓝宝石激光。

    Method for analyzing sample in liquid
    3.
    发明授权
    Method for analyzing sample in liquid 有权
    分析液体样品的方法

    公开(公告)号：US08037739B2

    公开(公告)日：2011-10-18

    申请号：US12197108

    申请日：2008-08-22

    申请人： Masahiro Ota ,  Noriaki Oyabu ,  Hiroaki Adachi ,  Masayuki Abe ,  Seizo Morita ,  Yusuke Mori ,  Takatomo Sasaki

    发明人： Masahiro Ota ,  Noriaki Oyabu ,  Hiroaki Adachi ,  Masayuki Abe ,  Seizo Morita ,  Yusuke Mori ,  Takatomo Sasaki

    IPC分类号： G01N11/00

    CPC分类号： G01Q30/14 ,  G01N1/36 ,  G02B21/33 ,  G02B21/34

    摘要： A method for analyzing a sample in a liquid is provided, which is suitable for easily and reliably preventing a liquid for analysis from being evaporated. When the sample in the liquid is observed by using a scanning probe microscope (SPM), a sealing liquid (17) immiscible with a liquid for analysis (16) is filled around the liquid for analysis (16), in which a sample (13) and a probe (15) are immersed, so as to form a sealing state, in which the liquid for analysis (16) is isolated from an external gas. The SPM enables the probe (15) disposed on a front end of a cantilever (14) to approach a surface of the sample (13) immersed in the liquid, scans the surface of the sample, and detects an interaction between the sample (13) and the probe (15), thereby generating an image.

    摘要翻译： 提供一种用于分析液体中的样品的方法，其适于容易且可靠地防止用于分析的液体蒸发。 当使用扫描探针显微镜（SPM）观察液体中的样品时，将用于分析的液体（16）不混溶的密封液体（17）填充在用于分析的液体（16）周围，其中样品（13 ）和探针（15），以便形成用于分析用液体（16）与外部气体隔离的密封状态。 SPM使得布置在悬臂（14）的前端上的探针（15）接近浸入液体中的样品（13）的表面，扫描样品的表面，并检测样品（13）之间的相互作用 ）和探头（15），从而产生图像。

    METHOD FOR OBSERVING PROTEIN CRYSTAL
    6.
    发明申请
    METHOD FOR OBSERVING PROTEIN CRYSTAL 有权
    观察蛋白水晶的方法

    公开(公告)号：US20130184445A1

    公开(公告)日：2013-07-18

    申请号：US13825280

    申请日：2011-09-20

    申请人： Norihiko Nishizawa ,  Hiroyoshi Matsumura ,  Yuusuke Mori ,  Shutaro Ishida ,  Kazuyoshi Itoh ,  Shigeru Sugiyama ,  Hiroaki Adachi ,  Tsuyoshi Inoue ,  Kazufumi Takano ,  Murakami Satoshi

    发明人： Norihiko Nishizawa ,  Hiroyoshi Matsumura ,  Yuusuke Mori ,  Shutaro Ishida ,  Kazuyoshi Itoh ,  Shigeru Sugiyama ,  Hiroaki Adachi ,  Tsuyoshi Inoue ,  Kazufumi Takano ,  Murakami Satoshi

    IPC分类号： G01B9/02 ,  C07K1/30

    CPC分类号： G01B9/02091 ,  C07K1/306 ,  G01N21/4795 ,  G01N2021/1787

    摘要： Provided are a method for observing protein crystal, wherein the growth process of the protein crystals is nondestructively and three-dimensionally monitored on a real-time basis and the growth of the crystals is controlled at a high accuracy to thereby enable the formation of single crystals having good qualities, which comprises observing the protein crystals, said protein crystals having been produced by a crystallization method using a gel, by an OCT measurement using light emitted from an ultrawideband light source;a method for observing protein crystals wherein the ultrawideband light source is an ultrawideband supercontinuum light source; a method for observing protein crystals wherein the center wavelength of the light emitted from the ultrawideband supercontinuum light source is a 0.8 μm band; and a method for observing protein crystals wherein the monitoring of the protein crystals is a monitoring by an in situ measurement.

    摘要翻译： 提供了一种用于观察蛋白质晶体的方法，其中蛋白质晶体的生长过程以实时的方式非破坏性和三维地监测，并且以高精度控制晶体的生长，从而能够形成单晶 具有良好的质量，其包括通过使用从超宽带光源发射的光的OCT测量观察蛋白质晶体，所述蛋白质晶体是通过使用凝胶的结晶方法产生的; 一种观察蛋白质晶体的方法，其中超宽带光源是超宽带超连续光源; 观察蛋白质晶体的方法，其中从超宽带超连续光源发射的光的中心波长为0.8μm波段; 以及观察蛋白质晶体的方法，其中蛋白质晶体的监测是通过原位测量的监测。

    Method for observing protein crystal
    7.
    发明授权
    Method for observing protein crystal 有权
    观察蛋白质晶体的方法

    公开(公告)号：US09182216B2

    公开(公告)日：2015-11-10

    申请号：US13825280

    申请日：2011-09-20

    申请人： Norihiko Nishizawa ,  Hiroyoshi Matsumura ,  Yuusuke Mori ,  Shutaro Ishida ,  Kazuyoshi Itoh ,  Shigeru Sugiyama ,  Hiroaki Adachi ,  Tsuyoshi Inoue ,  Kazufumi Takano ,  Murakami Satoshi

    发明人： Norihiko Nishizawa ,  Hiroyoshi Matsumura ,  Yuusuke Mori ,  Shutaro Ishida ,  Kazuyoshi Itoh ,  Shigeru Sugiyama ,  Hiroaki Adachi ,  Tsuyoshi Inoue ,  Kazufumi Takano ,  Murakami Satoshi

    IPC分类号： G01B9/02 ,  G01N21/47 ,  C07K1/30 ,  G01N21/17

    CPC分类号： G01B9/02091 ,  C07K1/306 ,  G01N21/4795 ,  G01N2021/1787

    摘要： Provided are a method for observing protein crystal, wherein the growth process of the protein crystals is nondestructively and three-dimensionally monitored on a real-time basis and the growth of the crystals is controlled at a high accuracy to thereby enable the formation of single crystals having good qualities, which comprises observing the protein crystals, said protein crystals having been produced by a crystallization method using a gel, by an OCT measurement using light emitted from an ultrawideband light source;a method for observing protein crystals wherein the ultrawideband light source is an ultrawideband supercontinuum light source;a method for observing protein crystals wherein the center wavelength of the light emitted from the ultrawideband supercontinuum light source is a 0.8 μm band; anda method for observing protein crystals wherein the monitoring of the protein crystals is a monitoring by an in situ measurement.

    摘要翻译： 提供了一种用于观察蛋白质晶体的方法，其中蛋白质晶体的生长过程以实时的方式非破坏性和三维地监测，并且以高精度控制晶体的生长，从而能够形成单晶 具有良好的质量，其包括通过使用从超宽带光源发射的光的OCT测量观察蛋白质晶体，所述蛋白质晶体是通过使用凝胶的结晶方法产生的; 一种观察蛋白质晶体的方法，其中超宽带光源是超宽带超连续光源; 观察从超宽带超连续光源发射的光的中心波长为0.8μm波段的蛋白质晶体的方法; 以及观察蛋白质晶体的方法，其中蛋白质晶体的监测是通过原位测量的监测。

    Information processing apparatus, computer-readable storage medium having information processing program stored therein, information processing method, and information processing system
    8.
    发明授权
    Information processing apparatus, computer-readable storage medium having information processing program stored therein, information processing method, and information processing system 有权
    信息处理装置，其中存储有信息处理程序的计算机可读存储介质，信息处理方法和信息处理系统

    公开(公告)号：US09542240B2

    公开(公告)日：2017-01-10

    申请号：US13102422

    申请日：2011-05-06

    申请人： Hiroaki Adachi

    发明人： Hiroaki Adachi

    IPC分类号： G06F9/54

    CPC分类号： G06F9/54

    摘要： An application process unit executes a predetermined application program and a communication process unit performs a predetermined data communication process with another communication target. A communication stop determination unit determines whether or not to stop the data communication process performed by the communication process unit, on the basis of an instruction from the application process unit. When it is determined by the communication stop determination unit to stop the data communication process, the data communication process is stopped.

    摘要翻译： 应用处理单元执行预定的应用程序，并且通信处理单元与另一个通信目标执行预定的数据通信处理。 通信停止确定单元基于来自应用处理单元的指令确定是否停止由通信处理单元执行的数据通信处理。 当由通信停止确定单元确定停止数据通信处理时，停止数据通信处理。

    Terminal apparatus and method for adding an effect to an image
    10.
    发明授权
    Terminal apparatus and method for adding an effect to an image 有权
    一种用于向图像添加效果的终端装置和方法

    公开(公告)号：US08902334B2

    公开(公告)日：2014-12-02

    申请号：US13107430

    申请日：2011-05-13

    申请人： Hiroaki Adachi

    发明人： Hiroaki Adachi

    IPC分类号： H04N5/262 ,  H04N5/232 ,  H04N5/235 ,  G06T11/00

    CPC分类号： H04N5/23219 ,  G06T11/00 ,  H04N5/235

    摘要： A terminal apparatus including: an image capturing unit configured to capture an image of a subject; a storage unit configured to store a table that associates information related to an image with at least one effect to be applied to an image; a control unit configured to detect or receive information related to the image captured by the image capturing unit, and select an effect from the table stored in the storage unit based on the detected or received information related to the image; and an image processing unit configured to apply the selected effect to the captured image.

    摘要翻译： 一种终端装置，包括：图像拍摄单元，被配置为捕获被摄体的图像; 存储单元，被配置为存储将与图像相关的信息与要应用于图像的至少一个效果相关联的表; 控制单元，被配置为检测或接收与由图像捕获单元捕获的图像有关的信息，并且基于与图像相关的检测或接收的信息从存储在存储单元中的表中选择效果; 以及图像处理单元，被配置为将所选择的效果应用于所捕获的图像。