公开(公告)号：US6129677A

公开(公告)日：2000-10-10

申请号：US131678

申请日：1998-08-10

申请人： Takeshi Sohma ,  Yoshihiro Sugo ,  Rie Tanaka ,  Wenxi Chen ,  Hiromitsu Kasuya ,  Kohei Ono

发明人： Takeshi Sohma ,  Yoshihiro Sugo ,  Rie Tanaka ,  Wenxi Chen ,  Hiromitsu Kasuya ,  Kohei Ono

IPC分类号： A61B5/0245 ,  A61B5/0285 ,  G06F17/00 ,  A61B5/0452

CPC分类号： A61B5/0285

摘要： An apparatus for non-invasion heart monitoring includes electrocardiogram measuring means (1) for measuring electrocardiograms, pulse wave measuring means (2) for measuring pulse waves, and a CPU (30) for processing electrocardiogram signals derived from the electrocardiogram measuring means (1) and pulse wave signals derived from the pulse-wave measuring means (2). The CPU (30) detects the amplitudes of the pulse waves corresponding to the R waves of the cardiogram and the pulse wave propagation times, and computes a ratio (Nr/N) of the heart rate N and the heart rate Nr exclusive of the heart beats of wave deficits.

摘要翻译： 一种用于非入侵心脏监测的装置包括用于测量心电图的心电图测量装置（1），用于测量脉搏波的脉搏波测量装置（2）和用于处理从心电图测量装置（1）得到的心电图信号的CPU（30） 和从脉波测量装置（2）导出的脉波信号。 CPU（30）检测与心电图的R波和脉波传播时间相对应的脉搏波的振幅，并计算出心脏N的比值（Nr / N）和排除心脏的心率Nr 波浪失败。

公开(公告)号：US5755669A

公开(公告)日：1998-05-26

申请号：US841684

申请日：1997-04-30

申请人： Kohei Ono ,  Hiromitsu Kasuya ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Wenxi Chen

发明人： Kohei Ono ,  Hiromitsu Kasuya ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Wenxi Chen

IPC分类号： A61B5/0225 ,  A61B5/0285 ,  A61B5/00

CPC分类号： A61B5/02125 ,  A61B5/02255 ,  A61B5/0285

摘要： After an initial blood pressure measurement using a cuff 2 has been made, not only a pulse wave propagation time Tt is counted consecutively, but also a pulse wave propagation time change .DELTA.T is calculated every time the pulse wave propagation time Tt is counted and compared with a pulse wave propagation change threshold .DELTA.Ts. When the pulse wave propagation time change .DELTA.T exceeds the pulse wave propagation time change threshold .DELTA.Ts, not only a blood pressure value BPt is measured with the cuff 2, but also a pulse wave propagation time Tt.sub.1 is counted. If there are at least two sets of data, each set of data consisting of a blood pressure value BPt and a pulse wave propagation time Tt.sub.1, coefficients .alpha., .beta. specific to a subject are calculated from such two sets of data by a least-squares method. Then, the pulse wave propagation time change threshold .DELTA.Ts is calculated from the coefficient .alpha., and the current pulse wave propagation time change threshold .DELTA.Ts is updated.

摘要翻译： 在进行了使用袖带2的初始血压测定之后，不仅脉冲波传播时间Tt连续计数，而且每当脉搏波传播时间Tt被计数并进行比较时也计算出脉搏波传播时间变化量DELTA T 具有脉波传播变化阈值DELTA Ts。 当脉波传播时间变化DELTA T超过脉波传播时间变化阈值DELTA Ts时，不仅用袖带2测定血压值BPt，而且对脉搏波传播时间Tt1进行计数。 如果存在至少两组数据，则由血压值BPt和脉搏波传播时间Tt1组成的每组数据由特定于对象的这两组数据通过最小二乘法计算 方法。 然后，根据系数α计算脉波传播时间变化阈值DELTA Ts，并且更新当前脉搏波传播时间变化阈值DELTA Ts。

公开(公告)号：US5876348A

公开(公告)日：1999-03-02

申请号：US993562

申请日：1997-12-18

申请人： Yoshihiro Sugo ,  Takeshi Sohma ,  Hiromitsu Kasuya ,  Rie Tanaka

发明人： Yoshihiro Sugo ,  Takeshi Sohma ,  Hiromitsu Kasuya ,  Rie Tanaka

IPC分类号： A61B5/022 ,  A61B5/0245 ,  A61B5/0285 ,  A61B5/0456 ,  A61B5/02

CPC分类号： A61B5/02125 ,  A61B5/022 ,  A61B5/0285 ,  A61B5/0456

摘要： During a noninvasive blood pressure measurement using a cuff 2, a pulse wave propagation time T1 from the appearance of the peak value of an R wave in an electrocardiogram (ECG) waveform to the appearance of the bottom value of a pulse wave is counted, and a blood pressure value BP1 is calculated from a count result T1 and parameters .alpha., .beta. specific to a subject obtained during a pulse wave propagation time calibration. Then, the absolute value of a difference between the blood pressure value BP1 and a blood pressure value NIBP1 obtained by the noninvasive blood pressure measurement using the cuff 2 is calculated, and it is indeed whether or not the calculated absolute value is within a predetermined threshold.sub.-- BP. If the absolute value is judged to exceed the threshold.sub.-- BP, then blood pressure is measured again noninvasively using the cuff 2, and a blood pressure value NIBP1'obtained from such repeated measurement is displayed on a display 22.

摘要翻译： 在使用袖带2的无创血压测定中，计数从心电图（ECG）波形中的R波的峰值出现到脉搏波的底部值的出现的脉搏波传播时间T1， 根据计数结果T1和在脉搏波传播时间校准期间获得的对象特有的参数α，β计算血压值BP1。 然后，计算通过使用袖带2的无创血压测定得到的血压值BP1与血压值NIBP1之差的绝对值，实际上是否计算出的绝对值在规定的阈值以内 -BP。 如果绝对值被判断为超过阈值-BP，则使用袖带2再次非侵入性地测量血压，并且在显示器22上显示从这种重复测量获得的血压值NIBP1。

公开(公告)号：US6083171A

公开(公告)日：2000-07-04

申请号：US742750

申请日：1996-11-01

申请人： Kohei Ono ,  Hiromitsu Kasuya ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Hidehiro Hosaka

发明人： Kohei Ono ,  Hiromitsu Kasuya ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Hidehiro Hosaka

IPC分类号： A61B5/022 ,  A61B5/0285 ,  A61B5/00

CPC分类号： A61B5/022 ,  A61B5/0285

摘要： A pulse wave propagation time is counted constantly. Not only it is judged whether or not a pulse wave propagation time change .DELTA.T exceeds a pulse wave propagation time change threshold .DELTA.Ts, but also it is judged whether or not cardiovascular dynamic changes .DELTA.HR, r.sub.1, r.sub.2 exceed thresholds thereof .DELTA.HRs, r.sub.1 s, r.sub.2 s, whereby a sudden turn for the worse in the blood pressure fluctuation of a subject is monitored. If any one of the changes exceeds the threshold thereof, a blood pressure measurement using a cuff 2 is made on the subject.

摘要翻译： 不断对脉搏波传播时间进行计数。 不仅判断脉波传播时间变化DELTA T是否超过脉波传播时间变化阈值DELTA Ts，而且判断心血管动态变化DELTA HR，r1，r2是否超过阈值DELTA HR， r1s，r2s，从而监测受试者的血压波动的突然转动。 如果任何一个变化超过其阈值，则对被检体进行使用袖带2的血压测量。

公开(公告)号：US5649543A

公开(公告)日：1997-07-22

申请号：US466746

申请日：1995-06-06

申请人： Hidehiro Hosaka ,  Hiroshi Sakata ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Hiromitsu Kasuya

发明人： Hidehiro Hosaka ,  Hiroshi Sakata ,  Yoshihiro Sugo ,  Takeshi Sohma ,  Hiromitsu Kasuya

IPC分类号： A61B5/0205 ,  A61B5/022 ,  A61B5/0225 ,  A61B5/0285 ,  A61B5/00

CPC分类号： A61B5/0285 ,  A61B5/02255

摘要： A pulse-wave propagation time basis blood pressure monitor includes a memory for storing an equation describing the relationship between the pulse wave propagation time and the parameter .alpha., input means for entering the blood pressure value for calibration, a time-interval detect reference point detecting means for detecting a reference point for detecting the time interval of a pulse wave in the aorta of a subject; pulse wave detecting means for detecting a pulse wave which appears in the peripheral blood vessel after it appears in the aorta; pulse-wave propagation time measuring section for measuring a pulse wave propagation time from the output signals of the time-interval detect reference point detecting means and the pulse wave detecting means, first computing means for determining the parameter .alpha. proper to the subject on the basis of the general equation stored in the memory by using the pulse wave propagation time for calibration gathered from the subject, second computing means for determining the parameter .beta. to be added in computing a blood pressure value by using the pulse wave propagation time, by using the blood pressure value inputted for calibration, the pulse wave propagation time measured for calibration, and the parameter .alpha. determined by the first computing means, third computing means for computing a blood pressure value by using the measured pulse wave propagation time, and the parameters .alpha. and .beta., and measured data output means for outputting data of the computed blood pressure value.

摘要翻译： 脉搏波传播时间基准血压监视器包括用于存储描述脉搏波传播时间和参数α之间的关系的方程式的存储器，用于输入用于校准的血压值的输入装置，时间间隔检测参考点检测 用于检测用于检测被检体的主动脉中的脉搏波的时间间隔的参考点的装置; 脉波检测装置，用于检测外周血管出现在主动脉中后出现的脉搏波; 用于根据时间间隔检测基准点检测装置和脉搏波检测装置的输出信号测量脉搏波传播时间的脉波传播时间测量部分，第一计算装置，用于在此基础上确定对象的参数α 通过使用从对象收集的校准的脉搏波传播时间存储在存储器中的一般方程式的第二计算装置，用于通过使用脉波传播时间来确定计算血压值时要添加的参数β的第二计算装置， 用于校准输入的血压值，用于校准的脉搏波传播时间和由第一计算装置确定的参数α，第三计算装置，用于通过使用测量的脉搏波传播时间计算血压值，以及参数α和 β和用于输出计算出的血压值的数据的测量数据输出装置。

公开(公告)号：US5603329A

公开(公告)日：1997-02-18

申请号：US492938

申请日：1995-06-21

申请人： Hidehiro Hosaka ,  Takashi Nakaya ,  Yoshihiro Sugo ,  Hiromitsu Kasuya ,  Rie Tanaka

发明人： Hidehiro Hosaka ,  Takashi Nakaya ,  Yoshihiro Sugo ,  Hiromitsu Kasuya ,  Rie Tanaka

IPC分类号： A61B5/0225 ,  A61B5/00

CPC分类号： A61B5/02125 ,  A61B5/02255

摘要： The multi-functional blood pressure monitor includes input unit for entering a value of blood pressure for calibration; unit for detecting a time interval detection reference point on an aortic pulse wave, unit for detecting a peripheral blood pulse wave as it appears later than the aortic pulse wave, unit (CPU) for measuring the pulse wave propagation time on the basis of the detection outputs from the unit for detecting a time interval detection reference point and the unit for detecting a peripheral blood pulse wave, first computing unit (CPU) for computing the values of parameters .alpha. and .beta. using the two values of blood pressure that have been entered for calibration and the two pulse wave propagation times that have been measured for calibration, second computing unit (CPU) for computing blood pressure from a measured pulse wave propagation time and the values of parameters .alpha. and .beta., and display for presenting both the computed blood pressure and the value of parameter .alpha. which serves as an index for arteriosclerosis.

摘要翻译： 多功能血压计包括用于输入用于校准的血压值的输入单元; 用于检测主动脉脉搏波上的时间间隔检测基准点的单元，用于检测比主动脉脉波更迟的外周血脉波的单元，用于基于检测来测量脉搏波传播时间的单位（CPU） 用于检测时间间隔检测参考点的单元的输出和用于检测外周血脉搏波的单元的第一计算单元（CPU），用于使用输入的两个血压值计算参数α和β的值 校准和测量的两个脉搏波传播时间，用于从测量的脉搏波传播时间计算血压的第二计算单元（CPU）和参数α和β的值，以及显示用于呈现计算出的血压 以及作为动脉硬化指标的参数α的值。

公开(公告)号：US5738106A

公开(公告)日：1998-04-14

申请号：US605928

申请日：1996-02-23

申请人： Shinji Yamamori ,  Kohei Ono ,  Masami Ito ,  Hiromitsu Kasuya ,  Masayuki Inoue ,  Masaki Sugiura

发明人： Shinji Yamamori ,  Kohei Ono ,  Masami Ito ,  Hiromitsu Kasuya ,  Masayuki Inoue ,  Masaki Sugiura

IPC分类号： G01N33/497 ,  A61B5/083

CPC分类号： A61B5/0836 ,  A61B5/7415

摘要： The capnometer of the invention is an equipment which detects a signal which time-varies in accordance with a carbon dioxide concentration from a respiration gas, thereby calculating the carbon dioxide concentration. The capnometer has: carbon dioxide concentration calculating device for detecting the maximum value for each expiration from a concentration signal corresponding to the calculated carbon dioxide concentration, for comparing the maximum value with concentration signals respectively corresponding to a plurality of predetermined concentration ranges, and for outputting one of different control signals for the concentration ranges; and reporting device for outputting a sound corresponding to the carbon dioxide concentration, in accordance with the control signal.

摘要翻译： 本发明的电位计是根据来自呼吸气体的二氧化碳浓度来检测随时间变化的信号的装置，从而计算二氧化碳浓度。 电位计具有：二氧化碳浓度计算装置，用于从与计算出的二氧化碳浓度对应的浓度信号中检测每次呼出的最大值，用于将最大值与分别对应于多个预定浓度范围的浓度信号进行比较，并输出 浓度范围的不同控制信号之一; 以及根据控制信号输出与二氧化碳浓度相对应的声音的报告装置。