摘要:
The present invention provides a GIP analog, which is derived from GIP (1-29, SEQ ID NO: 1), has both GLP-1 agonist activity and GIPR stimulation activity, and comprises an amino acid sequence represented by the following formula I: Tyr-A2-A3-Gly-Thr-Phe-A7-Ser-Asp-Tyr-Ser-A12-A13-A14-A15-Lys-A17-A18-A19-A20-A21-A22-A23-A24-Trp-Leu- A27-A28-A29-Y. The present invention also provides a pharmaceutical composition comprising the GIP analog and use thereof.
摘要翻译:本发明提供衍生自GIP(1-29,SEQ ID NO:1)的GIP类似物具有GLP-1激动剂活性和GIPR刺激活性,并且包含由下式I表示的氨基酸序列: Tyr-A2-A3-Gly-Thr-Phe-A7-Ser-Asp-Tyr-Ser-A12-A13-A14-A15-Lys-A17-A18-A19-A20-A21-A22-A23-A24-Trp- Leu- A27-A28-A29-Y。 本发明还提供了包含GIP类似物及其用途的药物组合物。
摘要:
The present invention provides a GIP analog, which is derived from GIP (1-29, SEQ ID NO: 1), has both GLP-1 agonist activity and GIPR stimulation activity, and comprises an amino acid sequence represented by the following formula I: Tyr-A2-A3-Gly-Thr-Phe-A7-Ser-Asp-Tyr-Ser-A12-A13-A14-A15-Lys-A17-A18-A19-A20-A21-A22-A23-A24-Trp-Leu-A27-A28-A29-Y. The present invention also provides a pharmaceutical composition comprising the GIP analog and use thereof.
摘要翻译:本发明提供衍生自GIP(1-29,SEQ ID NO:1)的GIP类似物具有GLP-1激动剂活性和GIPR刺激活性,并且包含由下式I表示的氨基酸序列: Tyr-A2-A3-Gly-Thr-Phe-A7-Ser-Asp-Tyr-Ser-A12-A13-A14-A15-Lys-A17-A18-A19-A20-A21-A22-A23-A24-Trp- Leu-A27-A28-A29-Y。 本发明还提供了包含GIP类似物及其用途的药物组合物。
摘要:
In a wireless multi-hop network, a transmission scheduling apparatus calculates a transmission demand of every node within the wireless multi-hop network, and allocates a time slot to each node by using the transmission demand of each node.
摘要:
In a wireless multi-hop network, a transmission scheduling apparatus calculates a transmission demand of every node within the wireless multi-hop network, and allocates a time slot to each node by using the transmission demand of each node.