摘要:
Compounds represented by Formula I: which are useful as are alpha-1A/B adrenoceptor antagonists, to methods of treating conditions associated with the activity of alpha-1A/B adrenoceptors, and to methods of making said compounds, wherein Ar, Z, R, R′, R5 and R10 are as defined herein.
摘要:
Compounds represented by Formula I: which are useful as are alpha-1A/B adrenoceptor antagonists, to methods of treating conditions associated with the activity of alpha-1A/B adrenoceptors, and to methods of making said compounds, wherein Ar, Z, R, R′, R5 and R10 are as defined herein.
摘要:
Compounds which are alpha-1A/B adrenoceptor antagonists and which are represented by Formula I: wherein Q is a monocyclic or bicyclic optionally-substituted heterocyclic ring as defined herein; Z is —C(═O)— or —S(═O)2—; R and R′ are lower alkyl; R5 is halogen, cyano, hydroxy, —R6, or —OR6; and R6 is alkyl, substituted alkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, heterocyclo, or substituted heterocyclo; and pharmaceutically-acceptable salts, hydrates, prodrugs, and isomers thereof.
摘要翻译:作为α-1A / B肾上腺素受体拮抗剂并由式I表示的化合物:其中Q是如本文所定义的单环或双环任选取代的杂环; Z是-C(-O) - 或-S(-O)2 - 。 R和R'是低级烷基; R 5是卤素,氰基,羟基,-R 6或-OR 6; R 6是烷基,取代的烷基,芳基,取代的芳基,杂芳基,取代的杂芳基,环烷基,取代的环烷基,杂环或取代的杂环; 及其药学上可接受的盐,水合物,前体药物和异构体。
摘要:
Chemokine receptor antagonists, in particular, 3,7-diazabicyclo[3.3.0]octane compounds according to formula (I) are antagonists of chemokine CCR5 receptors which are useful for treating or preventing an human immunodeficiency virus (HIV) infection, or treating AIDS or ARC. The invention further provides methods for treating diseases that are allieviated with CCR5 antagonists. The invention includes pharmaceutical compositions and methods of using the compounds for the treatment of these diseases. The invention further includes processes for the preparation of compounds according to formula I.
摘要:
Chemokine receptor antagonists, in particular, 3,7-diazabicyclo[3.3.0]octane compounds according to formula (I) are antagonists of chemokine CCR5 receptors which are useful for treating or preventing an human immunodeficiency virus (HIV) infection, or treating AIDS or ARC. The invention further provides methods for treating diseases that are allieviated with CCR5 antagonists. The invention includes pharmaceutical compositions and methods of using the compounds for the treatment of these diseases. The invention further includes processes for the preparation of compounds according to formula I.
摘要:
A plasma display panel having higher light-emitting luminance and efficiency of a discharge cell includes: a plurality of first barriers successively formed on a substrate at predetermined intervals; a plurality of first sustain electrodes formed at a width more than 40% of a pixel pitch, which is an overall distance of four of the barriers, to be orthogonal to the first barriers; a plurality of second sustain electrodes spaced apart from the first sustain electrodes at a distance less than 20% of the pixel pitch and mated with the first sustain electrodes one by one; a dielectric layer formed at a thickness of 25 μm or more to cover the first and second sustain electrodes; and a plurality of pads formed on some of the dielectric layer corresponding to the first sustain electrodes and the second sustain electrodes in each discharge cell.
摘要:
A method of manufacturing silicon nanowires is characterized in that silicon nanowires are formed and grown through a solid-liquid-solid process or a vapor-liquid-solid process using a porous glass template having nanopores doped with erbium or an erbium precursor. In addition, a device including silicon nanowires formed using the above exemplary method according to the present invention can be effectively applied to various devices, for example, electronic devices such as field effect transistors, sensors, photodetectors, light emitting diodes, laser diodes, etc.
摘要:
Provided is a siloxane dispersant having a structure including a head part having an affinity for nanoparticles and a tail part having an affinity for a polydimethylsiloxane (PDMS) resin, and a nanoparticle paste composition comprising the same. The dispersant significantly improves dispersion efficiency of a polydimethylsiloxane resin system which is used in preparation of high-output light sources such as UV LEDs and the like.
摘要:
A method of forming a dielectric layer in PDP is provided. The method according to the present invention comprises, (a) forming a green sheet comprising a base film and a film-forming layer disposed on a surface of the base film, wherein the film-forming layer is formed on the surface of the base film by applying onto said surface of the base film a slurry containing a PbO-based glass powder, a binder, a dispersing agent, a plasticizer and a solvent; (b) transferring the film-forming layer of the green sheet onto a surface of a substrate, wherein electrodes are disposed on the surface of the substrate; and (c) sintering the film-forming layer.
摘要:
Disclosed herein is an electrode that includes a catalytic layer formed on a substrate coated with a conductive material, wherein the catalytic layer includes vertically aligned carbon nanotubes. A method of manufacturing the electrode and a solar cell comprising the electrode are also described. The electrode has increased surface roughness and a shortened charge transport pathway and, therefore, reduced charge transport resistance. Thus, when the electrode is used in a solar cell, it can improve the efficiency of the solar cell.