公开(公告)号：US07825155B2

公开(公告)日：2010-11-02

申请号：US12066251

申请日：2006-09-13

申请人： Teruhisa Tokunaga ,  Tsuyoshi Takasaki ,  Kozo Yoshida ,  Ryu Nagata

发明人： Teruhisa Tokunaga ,  Tsuyoshi Takasaki ,  Kozo Yoshida ,  Ryu Nagata

IPC分类号： C07D403/06 ,  C07D403/02 ,  C07D405/04 ,  C07D413/04 ,  C07D403/04 ,  C07D417/06 ,  C07D417/02 ,  C07D417/04 ,  C07D401/12 ,  C07D401/02 ,  C07D401/06 ,  C07D409/04 ,  C07D413/02 ,  C07D413/06 ,  C07D209/34 ,  C07D209/38 ,  A61K31/541 ,  A61K31/5377 ,  A61K31/497 ,  A61K31/496 ,  A61K31/4439 ,  A61K31/454 ,  A61K31/427 ,  A61K31/422 ,  A61K31/4245 ,  A61K31/4178 ,  A61K31/4155 ,  A61K31/404

CPC分类号： C07D403/06 ,  C07D209/34 ,  C07D209/38 ,  C07D405/04 ,  C07D413/04 ,  C07D413/06 ,  C07D417/04

摘要： Disclosed is a compound represented by the formula (1) below, a prodrug thereof or a pharmaceutically acceptable salt of either, which is useful as a therapeutic, preventive or ameliorating agent for diabetes and the like. (In the formula, R3 represents an optionally substituted carbamoyl group or the like; X represents a hydroxyl group or the like; W1 and W2 independently represent a single bond or methylene; R7 and R8 independently represent a hydrogen atom, an optionally substituted alkyl group or the like; and Ar represents an optionally substituted aryl group or the like.)

摘要翻译： 公开了由下式（1）表示的化合物，其前药或其药学上可接受的盐，其可用作糖尿病等的治疗性预防或改善剂。 （式中，R 3表示可以具有取代基的氨基甲酰基等，X表示羟基等; W 1和W 2分别表示单键或亚甲基，R 7，R 8分别表示氢原子，可以具有取代基的烷基 或类似物; Ar表示任选取代的芳基等）。

公开(公告)号：US20090131398A1

公开(公告)日：2009-05-21

申请号：US12066251

申请日：2006-09-13

申请人： Teruhisa Tokunaga ,  Tsuyoshi Takasaki ,  Kozo Yoshida ,  Ryu Nagata

发明人： Teruhisa Tokunaga ,  Tsuyoshi Takasaki ,  Kozo Yoshida ,  Ryu Nagata

IPC分类号： A61K31/404 ,  C07D209/38 ,  A61P3/10 ,  C07D403/06

CPC分类号： C07D403/06 ,  C07D209/34 ,  C07D209/38 ,  C07D405/04 ,  C07D413/04 ,  C07D413/06 ,  C07D417/04

摘要： Disclosed is a compound represented by the formula (1) below, a prodrug thereof or a pharmaceutically acceptable salt of either, which is useful as a therapeutic, preventive or ameliorating agent for diabetes and the like. (In the formula, R3 represents an optionally substituted carbamoyl group or the like; X represents a hydroxyl group or the like; W1 and W2 independently represent a single bond or methylene; R7 and R8 independently represent a hydrogen atom, an optionally substituted alkyl group or the like; and Ar represents an optionally substituted aryl group or the like.)

摘要翻译： 公开了由下式（1）表示的化合物，其前药或其药学上可接受的盐，其可用作糖尿病等的治疗性预防或改善剂。 （式中，R 3表示可以具有取代基的氨基甲酰基等，X表示羟基等; W 1和W 2分别表示单键或亚甲基，R 7，R 8分别表示氢原子，可以具有取代基的烷基 或类似物; Ar表示任选取代的芳基等）。

公开(公告)号：US07220773B2

公开(公告)日：2007-05-22

申请号：US10474943

申请日：2002-04-17

申请人： Ryu Nagata ,  Katsunori Maruta ,  Kiyotaka Iwai ,  Makoto Kitoh ,  Kantaro Ushiroda ,  Kozo Yoshida

发明人： Ryu Nagata ,  Katsunori Maruta ,  Kiyotaka Iwai ,  Makoto Kitoh ,  Kantaro Ushiroda ,  Kozo Yoshida

IPC分类号： C07D207/46 ,  A61K31/40

CPC分类号： C07D207/33 ,  C07D207/333 ,  C07D207/335 ,  C07D207/34 ,  C07D401/06 ,  C07D401/12 ,  C07D403/06 ,  C07D405/06 ,  C07D405/12 ,  C07D409/06 ,  C07D417/06

摘要： A novel pyrrole derivative represented by the following formula (1) and a salt thereof: wherein R1 means substituted alkenyl, etc.; R2 means substituted benzoyl, etc.; and R3 to R5 each means hydrogen, alkyl, halogeno, etc. The derivative and salt have antidiabetic activity.

摘要翻译： 由下式（1）表示的新型吡咯衍生物及其盐：其中R 1表示取代的烯基等; R 2表示取代的苯甲酰基等; R 3和R 5各自表示氢，烷基，卤代等。衍生物和盐具有抗糖尿病活性。

公开(公告)号：US20130160428A1

公开(公告)日：2013-06-27

申请号：US13820775

申请日：2011-09-02

申请人： Mitsugu Okuda ,  Kozo Yoshida

发明人： Mitsugu Okuda ,  Kozo Yoshida

IPC分类号： F01N13/18

CPC分类号： F01N13/1805 ,  B60K13/04 ,  F01N13/1822 ,  F01N2340/00 ,  F01N2590/08 ,  Y10T29/49398 ,  Y10T29/49778 ,  Y10T29/4978

摘要： An engine with an exhaust treatment device (2) wherein a rotation moment of a side support stay (12) is generated by a load of a side portion (50) received by side support stay fastening tool (13) via an edge portion (21) of a cutout groove (20). As a result, a load of the side portion (50) of the exhaust treatment device (2) can be supported by the side support stay (12). A one-side temporary mount portions (22) is provided in a one-side support stay (10). The one-side support stay (10) can be temporarily mounted on the one-side temporary mount portions (22).

摘要翻译： 一种具有排气处理装置（2）的发动机，其特征在于，侧支撑支架（12）的旋转力矩是由侧支撑支撑紧固工具（13）经由边缘部分（21）接收的侧部（50）的负载产生的 ）切口凹槽（20）。 结果，排气处理装置（2）的侧部（50）的负载能够被侧支撑撑（12）支撑。 单侧临时安装部分（22）设置在一侧支撑撑架（10）中。 单侧支撑​​撑条（10）可以临时安装在单面临时安装部分（22）上。

公开(公告)号：US06172710B2

公开(公告)日：2001-01-09

申请号：US09159992

申请日：1998-09-24

申请人： Kozo Yoshida

发明人： Kozo Yoshida

IPC分类号： H04N701

CPC分类号： H04N5/268 ,  H04N5/9205 ,  H04N7/0806 ,  H04N7/088

摘要： An object of the invention is to realize a frame converter which successively can output an image signal in synchronous situation with a switching of asynchronous image signals by using a frame memory of which a number is smaller than of the inputted image signal. A frame converter according to the invention characterized by comprising, signal inputting means 11 and 12 for receiving image signals, identification signal assigning means 14 and 24 for assigning an identification signal to non-image area of the image signal from the signal inputting means for identifying the image signal, storing means 16 and 25 for storing the image signal form the signal inputting means for each frame, and signal outputting means 31 for outputting the image signal which is stored in the storing means by reading alternatively.

摘要翻译： 本发明的目的是实现一种帧转换器，其可以通过使用数字小于输入图像信号的帧存储器，以异步图像信号的切换在同步情况下输出图像信号。 根据本发明的帧转换器，其特征在于包括用于接收图像信号的信号输入装置11和12，用于从用于识别的信号输入装置的图像信号的非图像区域分配识别信号的识别信号分配装置14和24 图像信号，用于存储图像信号的存储装置16和25构成每帧的信号输入装置，以及信号输出装置31，用于通过交替地读取存储在存储装置中的图像信号。

公开(公告)号：US07644706B1

公开(公告)日：2010-01-12

申请号：US12339645

申请日：2008-12-19

申请人： Kozo Yoshida ,  Hiroshi Manabe ,  Mitsugu Okuda

发明人： Kozo Yoshida ,  Hiroshi Manabe ,  Mitsugu Okuda

IPC分类号： F01M13/00

CPC分类号： F01M13/0011 ,  F01M13/022 ,  F01M13/0416 ,  F01M2013/027 ,  F01M2013/0461

摘要： The blow-by gas that has flowed from a front-stage breather-chamber inlet (33) into a front-stage breather chamber (28) floats up around a preliminary valve-seat peripheral wall (22) and a preliminary breather-passage peripheral wall (24) and flows from a breather-chamber inlet (21) into a breather chamber (3). When a breather-chamber peripheral wall (12) is removed from a breather-chamber attaching seat (11), a diaphragm valve (16) is attached to the breather-chamber attaching seat (11) and has a valve face (18) seated on a preliminary valve seat (23), and a plug (27) is taken out of a preliminary breather outlet (25), from which a breather pipe (5) is led out, thereby enabling the front-stage breather chamber (28) to be used for a single-stage breather chamber provided with the diaphragm valve (16).

摘要翻译： 从前级通气室入口（33）流入前级通气室（28）的窜气气浮在预置阀座周壁（22）和预备通气通道周边 壁（24）并从通气室入口（21）流入通气室（3）。 当通气室周壁（12）从通气室安装座（11）上取下时，隔膜阀（16）安装在通气室安装座（11）上并具有阀座（18）就座 在预备阀座（23）上，并且从预备通气孔（25）中取出插头（27），通气管（5）从该通气孔排出，由此能够使前级通气室（28） 用于设置有隔膜阀（16）的单级通气室。

公开(公告)号：US20050241277A1

公开(公告)日：2005-11-03

申请号：US10497649

申请日：2002-12-03

申请人： Keiji Yano ,  Kozo Yoshida ,  Takashige Yano

发明人： Keiji Yano ,  Kozo Yoshida ,  Takashige Yano

IPC分类号： B65B51/24 ,  B26D7/20 ,  B29C65/00 ,  B29C65/02 ,  B29C65/74 ,  B65B51/10 ,  B65B51/30

CPC分类号： B29C66/72321 ,  B26D7/20 ,  B29C65/3656 ,  B29C65/368 ,  B29C65/7451 ,  B29C66/1122 ,  B29C66/4312 ,  B29C66/71 ,  B29C66/72328 ,  B29C66/7373 ,  B29C66/80 ,  B29C66/81427 ,  B29C66/81431 ,  B29C66/81457 ,  B29C66/81811 ,  B29C66/83543 ,  B29C66/8491 ,  B29L2031/7166 ,  B65B9/2049 ,  B65B9/207 ,  B65B51/303 ,  B29K2023/06

摘要： The sealing apparatus comprises (a) a heat seal jaw, (b) a heat seal bar having two heaters arranged in parallel, being provided in a front edge of said heat seal jaw and having a working surface, (c) a counter jaw disposed oppositely to the heat seal jaw, (d) a counter rail provided to said counter jaw and having the working surface, (e) a drive means for advancing/retracting the heat seal jaw and counter jaw relatively, (f) a heating means for actuating the heaters while clamping a packaging material by the working surface of the heat seal bar and the working of the counter rail and, (g) a cutter section comprising of a cutter disposed at the position between the two heaters and a resilient counter cutter, and is characterized in that the counter cutter is held by a holding section provided on the working surface of the heat seal bar or the counter rail and projecting from the holding working surface. The seal apparatus can improve hygiene and the flap formation of the packaging container.

摘要翻译： 所述密封装置包括（a）热封颚，（b）具有平行布置的两个加热器的热密封条，设置在所述热封颚的前边缘中并具有工作表面，（c） （d）设置在所述反向钳口上并具有工作表面的反向导轨，（e）用于相对地推进/缩回热封颚和逆颚的驱动装置，（f）加热装置， 在通过热密封条的工作表面和对向导轨的工作夹持包装材料的同时致动加热器，以及（g）包括设置在两个加热器之间的位置上的切割器和一个弹性反向切割器的切割器部分， 其特征在于，所述反切割机由设置在所述热封条或所述反向导轨的工作面上的保持部保持，并从所述保持工作面突出。 密封装置可以改善包装容器的卫生和皮瓣形成。

公开(公告)号：US06949526B2

公开(公告)日：2005-09-27

申请号：US10333242

申请日：2001-07-30

申请人： Kazunori Kimura ,  Masami Narita ,  Kozo Yoshida

发明人： Kazunori Kimura ,  Masami Narita ,  Kozo Yoshida

IPC分类号： A61K31/5575 ,  A61K47/48 ,  A61P15/10 ,  A61K31/70 ,  A61K31/557

CPC分类号： B82Y5/00 ,  A61K31/5575 ,  A61K47/6951

摘要： Therapeutic agents for erectile dysfunction containing as the active ingredient prostaglandin derivatives of formula (I) (wherein, R1 is ethyl or n-2-propenyl.), esters thereof, nontoxic salts thereof, or cyclodextrin clathrate compounds thereof. The compounds of the formula (I) are useful for the treatment of erectile dysfunction.

摘要翻译： 含有作为活性成分的式（I）的前列腺素衍生物（其中R 1是乙基或n-2-丙烯基）的勃起功能障碍的治疗剂，其酯，无毒盐或环糊精包合物 其化合物。 式（I）的化合物可用于治疗勃起功能障碍。

公开(公告)号：US06529448B1

公开(公告)日：2003-03-04

申请号：US09674433

申请日：2000-11-01

申请人： Kazuyoshi Ishii ,  Kozo Yoshida

发明人： Kazuyoshi Ishii ,  Kozo Yoshida

IPC分类号： G11B1100

CPC分类号： G11B11/10534 ,  G11B5/17 ,  G11B11/10554 ,  G11B11/1058

摘要： In a flat magnetic head coil constituted by spiral coil patterns made of a conductive material film and two terminals connected to the coil patterns, the coil patterns have a substantially rectangular sectional shape. A minimum pitch P [&mgr;m] of the coil pattern, a width W [&mgr;m] of the sectional shape at the minimum pitch P, and a height H [&mgr;m] satisfy 15 [&mgr;m]≦P≦70 [&mgr;m] and 1.8−0.012P≦H/W≦7.5−0.06P. When an impedance Z0 between the two terminals of the coil while a core made of a magnetic material is not attached is equivalently constituted by an inductance L0, an RF resistance Rp0 parallel to the inductance L0, and a DC resistance Rs which is series-connected to the inductance L0 and is independent of a frequency, the inductance L0 [&mgr;H] at 10 MHz satisfies L0≦0.85 [&mgr;H].

摘要翻译： 在由导电材料膜和连接到线圈图案的两个端子构成的螺旋线圈图案构成的扁平磁头线圈中，线圈图案具有大致矩形的截面形状。 线圈图案的最小间距P [mum]，最小间距P处的截面形状的宽度W [mum]和高度H [mum]满足15μm/p≤70μm和 1.8-0.012P <= H / W <= 7.5-0.06P。 当没有安装由磁性材料制成的芯线的线圈两端之间的阻抗Z0等效地由电感L0，与电感L0平行的RF电阻Rp0和串联连接的直流电阻Rs 与电感L0无关，并且与频率无关，10MHz的电感L0H满足L0≤0.85μ。

公开(公告)号：US06317160B1

公开(公告)日：2001-11-13

申请号：US09198930

申请日：1998-11-24

申请人： Kozo Yoshida ,  Mitsuo Yamamoto ,  Yasutake Inaba

发明人： Kozo Yoshida ,  Mitsuo Yamamoto ,  Yasutake Inaba

IPC分类号： H04N9475

CPC分类号： H04N5/9205

摘要： A frame conversion device for switching between a plurality of image signals that are not synchronous and outputting each image signal continuously and synchronously. In addition, a desired signal is extracted from the continuous image signals and then output in parallel with the continuous image signals. The frame conversion device utilizes a frame conversion unit for recording an image signal optionally selected from a plurality of input image signals. A frame unit is utilized for reproducing a recorded signal outputted from the frame conversion unit independent of the operation of the frame conversion unit. The frame conversion unit includes an identification signal assigning part which assigns an identification signal to a non-image region of an image signal selected from a plurality of input signals. Frame-converting storage parts store the selected image signal. A signal output part selectively reads the image signal stored in each frame-converting storage device. The frame unit includes an identification signal detecting part that detects the identification signal included in the image signal produced in the frame conversion unit. A reproduction controlling part extracts a frame timing of the image signal assigned a predetermined identification signal. A recording storage part, at the extracted frame timing, stores an image signal corresponding to the predetermined identification signal and continuously outputs the image signal.

摘要翻译： 一种帧转换装置，用于在不同步的多个图像信号之间切换并连续且同步地输出每个图像信号。 此外，从连续图像信号中提取期望的信号，然后与连续图像信号并行地输出。 帧转换装置利用帧转换单元来记录可选地从多个输入图像信号中选择的图像信号。 帧单元用于再现与帧转换单元的操作无关的从帧转换单元输出的记录信号。 帧转换单元包括识别信号分配部分，其将识别信号分配给从多个输入信号中选择的图像信号的非图像区域。 帧转换存储部件存储所选择的图像信号。 信号输出部件选择性地读取存储在每个帧转换存储装置中的图像信号。 帧单元包括识别信号检测部分，其检测包括在帧转换单元中产生的图像信号中的识别信号。 再现控制部分提取分配了预定识别信号的图像信号的帧定时。 记录存储部分在提取的帧定时存储对应于预定识别信号的图像信号，并连续地输出图像信号。