Imidazopyrazines as protein kinase inhibitors
    7.
    发明授权
    Imidazopyrazines as protein kinase inhibitors 失效
    咪唑吡嗪作为蛋白激酶抑制剂

    公开(公告)号:US07557104B2

    公开(公告)日:2009-07-07

    申请号:US11758243

    申请日:2007-06-05

    IPC分类号: A61K31/497

    CPC分类号: C07D487/04

    摘要: In its many embodiments, the present invention provides a novel class of imidazopyrazine compounds as inhibitors of protein and/or checkpoint kinases, methods of preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of preparing pharmaceutical formulations including one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the protein or checkpoint kinases using such compounds or pharmaceutical compositions.

    摘要翻译: 在其许多实施方案中,本发明提供了一类新颖的咪唑并吡嗪化合物作为蛋白质和/或检查点激酶的抑制剂,制备此类化合物的方法,包含一种或多种此类化合物的药物组合物,制备药物制剂的方法,包括一种或多种 化合物,以及使用这些化合物或药物组合物治疗,预防,抑制或改善与蛋白质或检查点激酶相关的一种或多种疾病的方法。