One-pack preparation for disinfection, neutralization and cleaning of contact lenses and method of disinfection, neutralization and cleaning
    1.
    发明授权
    One-pack preparation for disinfection, neutralization and cleaning of contact lenses and method of disinfection, neutralization and cleaning 失效
    一次性消毒,中和和隐形眼镜清洗准备以及消毒,中和和清洁方法

    公开(公告)号:US06258591B1

    公开(公告)日:2001-07-10

    申请号:US09194779

    申请日:1998-12-03

    IPC分类号: C12S900

    摘要: The present invention provides a combined formulation for disinfecting, neutralizing and cleaning a soft contact lens and a method using the same easily, efficiently and safely. The formulation is a one-solution type of combined formulation for disinfecting, neutralizing and cleaning a soft contact lens, which includes a first formulation that contains an iodine-based disinfectant and a proteolytic enzyme and a second formulation that contains a reducing and a foaming agent treated with a delayed release coating, and which contains a nonionic surfactant in at least one of the first and second formulations. A stained soft contact lens can be disinfected, neutralized and cleaned easily by holding it in an aqueous solution colored yellow or brown by iodine molecules and removing it from the aqueous solution after the solution becomes almost colorless.

    摘要翻译: 本发明提供了一种用于消毒,中和和清洁软性隐形眼镜的组合制剂,以及使用该隐形眼镜的方法。 该制剂是用于消毒,中和和清洁软性隐形眼镜的单一溶液型组合制剂,其包括含有碘基消毒剂和蛋白水解酶的第一制剂和含有还原剂和发泡剂的第二制剂 用延迟释放涂层处理,并且在第一和第二配方中的至少一种中含有非离子表面活性剂。 染色的软性隐形眼镜可以通过将其保持在由碘分子着色为黄色或棕色的水溶液中而容易地消毒,中和和清洁,并且在溶液变得几乎无色后将其从水溶液中除去。

    Perfusate preparation for ophthalmic operation
    2.
    发明授权
    Perfusate preparation for ophthalmic operation 失效
    用于眼科手术的灌注液制剂

    公开(公告)号:US06495598B1

    公开(公告)日:2002-12-17

    申请号:US09807739

    申请日:2001-04-18

    IPC分类号: A61K3122

    CPC分类号: A61K9/0048 Y10S514/912

    摘要: A one-pack preparation of irrigating solution for ocular surgery of cataract, glaucoma or intraocular lens transplantation, which is excellent in the protection of ophthalmic tissues and endothelial cells during and after the operation and has a high in vivo stability. The preparation comprises an aqueous solution containing at least one compound selected from D-3-hydroxybutyric acid and water-soluble salts thereof, at least one compound selected from water-soluble bicarbonates, phosphoric acid and water-soluble phosphates, a water-soluble calcium salt, and a water-soluble magnesium salt.

    摘要翻译: 用于白内障,青光眼或眼内晶状体移植的眼部手术的冲洗溶液的一次性制剂,其在手术期间和手术后保护眼组织和内皮细胞,并且具有高的体内稳定性。 该制剂包含含有至少一种选自D-3-羟基丁酸及其水溶性盐的化合物的水溶液,至少一种选自水溶性碳酸氢盐,磷酸和水溶性磷酸盐的化合物,水溶性钙 盐和水溶性镁盐。

    4'-demethylepipodophyllotoxin glycosides
    4.
    发明授权
    4'-demethylepipodophyllotoxin glycosides 失效
    4'-去甲基磷酸胆碱酯糖苷

    公开(公告)号:US5081234A

    公开(公告)日:1992-01-14

    申请号:US516852

    申请日:1990-04-30

    CPC分类号: C07H17/04

    摘要: The present invention relates to antitumor 4'-demethylepipodophyllotoxin glycosides having the formula ##STR1## wherein R is a pentose selected from the group consisting of .beta.-D-ribopyranosyl, peracyl .beta.-D-ribopyranosyl, .beta.-D-xylopyranosyl, peracyl .beta.-D-xylopyranosyl, .alpha.-D-xylopyranosyl, peracyl .alpha.-D-xylopyranosyl, .alpha.-D-arabinopyranosyl, 3,4-O-(C.sub.1-4)alkylidene-D-ribopyranosyl, 2-O-acyl-3,4-O-(C.sub.1-4)alkylidene-D-ribopyranosyl, and .beta.-D-ribofuranosyl; P is hydrogen, or --PO.sub.3 H.sub.2 or a pharmaceutically acceptable salt thereof.