Compound with antimalarial activity and antimalarial drug containing the same as active ingredient
    1.
    发明授权
    Compound with antimalarial activity and antimalarial drug containing the same as active ingredient 失效
    具有抗疟活性的化合物和含有与活性成分相同的抗疟药

    公开(公告)号:US07973027B2

    公开(公告)日:2011-07-05

    申请号:US12224387

    申请日:2007-02-26

    IPC分类号: A61K31/47 C07D215/46

    CPC分类号: C07D401/12

    摘要: Compounds with high antimalarial activity; and antimalarial drugs containing the same as an active ingredient. There are provided compounds with antimalarial activity represented by the chemical formula: (wherein R1 is H, Cl or OCH3; R2 is H or CH3; R3 is CH, CH2, C(CH3), CH(CH3) or C(CH3)2; Ar is imidazole, triazole, pyridine, benzene, pyrrole, furan, thiophene or derivatives thereof; n is 1 to 5; and m is 1 to 5). Further, there are provided antimalarial drugs containing these compounds with antimalarial activity or pharmacologically acceptable salts thereof as active ingredients.

    摘要翻译: 抗疟活性高的化合物 和含有与活性成分相同的抗疟药。 提供具有化学式表示的抗疟活性化合物:其中R1为H,Cl或OCH3; R2为H或CH3; R3为CH,CH2,C(CH3),CH(CH3)或C(CH3)2 ; Ar为咪唑,三唑,吡啶,苯,吡咯,呋喃,噻吩或其衍生物; n为1至5; m为1至5)。 此外,提供了含有抗疟活性化合物的抗疟药物或其药理学上可接受的盐作为活性成分。

    Compound With Antimalarial Activity And Antimalarial Drug Containing The Same As Active Ingredient
    2.
    发明申请
    Compound With Antimalarial Activity And Antimalarial Drug Containing The Same As Active Ingredient 失效
    具有抗疟活性的化合物和含有作为活性成分的抗疟药

    公开(公告)号:US20090275612A1

    公开(公告)日:2009-11-05

    申请号:US12224387

    申请日:2007-02-26

    CPC分类号: C07D401/12

    摘要: Compounds with high antimalarial activity; and antimalarial drugs containing the same as an active ingredient. There are provided compounds with antimalarial activity represented by the chemical formula: (wherein R1 is H, Cl or OCH3; R2 is H or CH3; R3 is CH, CH2, C(CH3), CH(CH3) or C(CH3)2; Ar is imidazole, triazole, pyridine, benzene, pyrrole, furan, thiophene or derivatives thereof; n is 1 to 5; and m is 1 to 5). Further, there are provided antimalarial drugs containing these compounds with antimalarial activity or pharmacologically acceptable salts thereof as active ingredients.

    摘要翻译: 抗疟活性高的化合物 和含有与活性成分相同的抗疟药。 提供具有化学式表示的抗疟活性化合物:其中R1为H,Cl或OCH3; R2为H或CH3; R3为CH,CH2,C(CH3),CH(CH3)或C(CH3)2 ; Ar为咪唑,三唑,吡啶,苯,吡咯,呋喃,噻吩或其衍生物; n为1至5; m为1至5)。 此外,提供了含有抗疟活性化合物的抗疟药物或其药理学上可接受的盐作为活性成分。