公开(公告)号：US06295125B1

公开(公告)日：2001-09-25

申请号：US09521917

申请日：2000-03-09

申请人： Tsunemi Tokieda ,  Yukio Nogami ,  Saburo Inoue

发明人： Tsunemi Tokieda ,  Yukio Nogami ,  Saburo Inoue

IPC分类号： G01N2141

CPC分类号： G01N21/4133 ,  G01N30/74

摘要： To provide a differential refractive index detector free from fears for occurrence of personal errors in the judgement of stable condition and capable of performing highly efficient analysis operation, and a liquid chromatograph equipped with the detector. A differential refractive index detector provided with a reference cell, a sample cell, a light source for irradiating light on these two cells, a detecting part for detecting light transmitted through respective cells, and a signal processing part for applying predetermined processing to the output signal from the detecting part, which comprises means for sequentially performing an initial solution purge operation of purging the sample cell and the reference cell with an eluent by passing the eluent through the cells at the start of operation of said detector, a stabilizing solution purge operation of allowing the eluent purge of sample cell and reference cell to proceed and at the same time, confirming the stable condition thereof, and a stability confirming operation of confirming whether or not the detector has stabilized in an analysis capable condition by passing the eluent only through the sample cell, and means for announcing that the detector has stabilized in the analysis capable condition. According to the differential refractive index detector of the present invention, the processing from the initial solution purge operation to the stability confirming operation can be automated and a highly efficient analysis operation can be attained.

摘要翻译： 提供一种在稳定状态判断和能够进行高效分析操作的判断中不存在人为错误发生的差示折射率检测器和配备有检测器的液相色谱仪。 具有参考单元，样本单元，用于在这两个单元上照射光的光源的差分折射率检测器，用于检测通过各个单元传输的光的检测部分和用于对输出信号进行预定处理的信号处理部分 所述检测部分包括用于在所述检测器开始操作时通过使洗脱液通过细胞，顺序地执行用洗脱液清洗样品池和参考池的初始溶液清除操作的装置，稳定溶液清洗操作 允许样品池和参比细胞的洗脱液吹扫进行并同时确认其稳定状态，以及稳定性确认操作，通过使洗脱液仅通过该分析能力条件来确认检测器是否在分析能力条件下稳定 样品池，以及用于通知检测器在分析盖中已经稳定的装置 有条件 根据本发明的差示折射率检测器，可以自动化从初始溶液清洗操作到稳定性确认操作的处理，并且可以实现高效的分析操作。