公开(公告)号：US20240159715A1

公开(公告)日：2024-05-16

申请号：US18280932

申请日：2022-03-17

Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA

Inventor： Payam Eliahoo ,  BO Han ,  Richard Leahy ,  Kirk Shung

IPC: G01N29/34 ,  G01N11/00 ,  G01H9/00

CPC classification number: G01N29/343 ,  G01N11/00 ,  G01H9/008 ,  G01N2011/0073 ,  G01N2203/0075 ,  G01N2203/0094 ,  G01N2291/02818 ,  G01N2291/02827 ,  G01N2291/044

Abstract: A system, apparatus, method, algorithm and/or device (collectively, “system”) for non-contact or contactless ultrasound viscoelastic spectroscopy measures the viscoelastic properties of soft matter through exerting modulated ultrasound pressure waves, so called stress signals and measuring the material deformation, so called strain imaging, over a wide range of frequencies, and may be applied to various fields including but not limited to material science, polymer designing, tissue engineering, cancer drug development and/or biological tissue assessment for disease diagnosis and prognosis. By measuring the elastic and viscous moduli, the phase difference between them, and Poisson's ratio over a wide range of frequencies, this allows for non-destructive tests on soft matter such as biological tissue, by ultrasound probes.