公开(公告)号：US11602566B2

公开(公告)日：2023-03-14

申请号：US16771518

申请日：2019-03-01

Applicant: UPM-Kymmene Corporation

Inventor： Kari Luukko ,  Markus Nuopponen ,  Nicolò Curzio ,  Marjo Yliperttula ,  Polina Ilina ,  Päivi Tammela

IPC: A61K47/61 ,  A61K38/46 ,  A61L15/28 ,  A61L15/44 ,  C12N11/12

Abstract: The present application provides a method for preparing a medical product for covering tissue, the method comprising providing nanofibrillar cellulose, providing a bioactive molecule, and covalently bonding the bioactive molecule to the nanofibrillar cellulose. The present application also provides a medical product for covering tissue comprising a bioactive molecule covalently bound to nanofibrillar cellulose.

公开(公告)号：US20220349651A1

公开(公告)日：2022-11-03

申请号：US17245445

申请日：2021-04-30

Applicant: UPM-Kymmene Corporation

Inventor： Markus Nuopponen ,  Marjo Yliperttula ,  Arto Merivaara ,  Ossi Korhonen ,  Jacopo Zini ,  Elle Koivunotko ,  Lisa Chinello ,  Giulia Scapin ,  Anne Meriluoto ,  Lauri Paasonen

IPC: F26B5/06 ,  C12N5/00

Abstract: A method for freeze-drying a hydrogel composition is disclosed, the method comprising providing the hydrogel composition, wherein the hydrogel composition comprises cellulose nanofibrils and/or cellulose nanocrystals, at least one saccharide, at least one amino acid, and biologics; and freeze-drying the hydrogel composition, thereby obtaining a freeze-dried hydrogel composition.

公开(公告)号：US11274396B2

公开(公告)日：2022-03-15

申请号：US15930962

申请日：2020-05-13

Applicant: UPM—Kymmene Corporation

Inventor： Markus Nuopponen ,  Juha Tamper ,  Isko Kajanto

IPC: D21B1/14 ,  D21H11/18 ,  D21D1/36

Abstract: In a method for producing nanofibrillar cellulose, cellulose based fibre material, in which internal bonds in cellulose fibres have been weakened by 5 preliminary modification of cellulose, is subjected to disintegration treatment in form of pulp comprising fibres and liquid. The fibre material is supplied at a consistency higher than 10 wt-%, preferably at least 15 wt-%, to a disintegration treatment where fibrils are detached from the fibre material by joint effect of repeated impacts to the fibre material by fast moving 10 successive elements and the weakened internal bonds of the cellulose fibres. The nanofibrillar cellulose is withdrawn from the disintegration treatment at dry matter which is equal or higher than the consistency of the fibre material.

公开(公告)号：US10808356B2

公开(公告)日：2020-10-20

申请号：US14890392

申请日：2014-05-13

Applicant: UPM-KYMMENE CORPORATION

Inventor： Markus Nuopponen ,  Juha Tamper ,  Taisto Tienvieri

IPC: D21C9/00 ,  D21H11/18 ,  D21D1/00 ,  D21D1/20 ,  C08B15/08 ,  D21H21/18 ,  D21H17/25

Abstract: In a method for producing nanofibrillar cellulose, cellulose based fiber material in dispersion is processed for separating fibrils. The method includes a first step where the fiber material is supplied to a disperser, where it flows through several counter-rotating rotors in such a way that the material is repeatedly subjected to shear and impact forces by the effect of the different counter-rotating rotors, and a second step, where the fiber material obtained from the first step is supplied to a homogenizer, where it is subjected to homogenization by the effect of pressure.

公开(公告)号：US20170349670A1

公开(公告)日：2017-12-07

申请号：US15536844

申请日：2015-12-18

Applicant: UPM-KYMMENE CORPORATION

Inventor： Isko Kajanto ,  Markus Nuopponen

IPC: C08B15/04 ,  B01J14/00 ,  B01J19/00 ,  G01N27/416

CPC classification number: C08B15/04 ,  B01J14/00 ,  B01J19/0006 ,  B01J2219/00186 ,  C08B17/06 ,  G01N27/4168 ,  Y02P20/582

Abstract: A method for controlling the catalytic oxidation of cellulose includes using a heterocyclic nitroxyl compound as catalyst oxidizing cellulose in a reaction mixture comprising liquid medium, the catalyst and hypochlorite as main oxidant analyzing one or more oxidative chlorine species dependent on the hypochlorite concentration of the reaction mixture on line in the reaction mixture or in a gas composition which is in contact with the reaction mixture; and controlling supply of hypochlorite to the reaction mixture on the basis of the analysis.

公开(公告)号：US09809655B2

公开(公告)日：2017-11-07

申请号：US14907405

申请日：2014-06-24

Applicant: UPM-Kymmene Corporation

Inventor： Antti Laukkanen ,  Markus Nuopponen ,  Martina Lille

IPC: D21H11/18 ,  C08B15/02 ,  C08B15/04 ,  C08B15/08 ,  D21H11/20 ,  D21H19/00 ,  D21H21/18 ,  D21H23/04 ,  C09D101/02 ,  C09D101/04 ,  D21H19/12 ,  D21H23/22

CPC classification number: C08B15/02 ,  C08B15/04 ,  C08B15/08 ,  C09D101/02 ,  C09D101/04 ,  D21H11/18 ,  D21H11/20 ,  D21H19/00 ,  D21H19/12 ,  D21H21/18 ,  D21H23/04 ,  D21H23/22

Abstract: The invention relates to a method for modifying nanofibrillar cellulose composition, comprising—preparing fibrous dispersion of ionically charged nanofibrillar cellulose (NFC), and—applying heat treatment at a temperature of at least 90° C. to the fibrous dispersion until the viscosity of NFC starts to decrease. The viscosity of the heat-treated NFC is reversible by applying shear forces to the NFC.

公开(公告)号：US09739011B2

公开(公告)日：2017-08-22

申请号：US14357706

申请日：2012-11-14

Applicant: UPM-KYMMENE CORPORATION

Inventor： Juha Tamper ,  Markus Nuopponen

IPC: B02C13/20 ,  D21D1/20 ,  D21D1/36

CPC classification number: D21D1/20 ,  B02C13/205 ,  D21D1/36

Abstract: In a method for producing nanofibril cellulose, cellulose based fiber material, in which internal bonds in the cellulose fiber have been weakened by chemical modification, are supplied, for separating fibrils, through several counter-rotating rotors outwards in the radial direction with respect to the rotation axis of the rotors in such a way that the material is repeatedly subjected to shearing and impacting forces by the effect of the blades of the different counter-rotating rotors, whereby it is simultaneously fibrillated.

公开(公告)号：US20170190799A1

公开(公告)日：2017-07-06

申请号：US15314222

申请日：2014-06-26

Applicant: UPM-KYMMENE CORPORATION

Inventor： Mikko Rissanen ,  Markus Nuopponen

IPC: C08B15/02 ,  C09J7/02 ,  C08B3/20

CPC classification number: C08B15/02 ,  C08B3/20 ,  C09J7/401 ,  C09J7/403 ,  C09J7/405 ,  C09J2203/334 ,  C09J2401/005 ,  C09J2401/006 ,  C09J2459/005

Abstract: The invention relates to a method for obtaining a release liner and to release liner comprising a primer layer and a cellulose based support layer, the primer layer comprising an organic compound having one or more functional vinylic groups, the organic compound comprising an acetal connecting a first moiety and a second moiety, the first moiety comprising nanofibrillar cellulose having functional hydroxyl groups and the second moiety comprising an organic fragment, the organic fragment comprising at least one functional vinylic group.

公开(公告)号：US09663588B2

公开(公告)日：2017-05-30

申请号：US14367555

申请日：2013-02-13

Applicant: UPM-KYMMENE CORPORATION

Inventor： Annikki Vehniäinen ,  Markus Nuopponen ,  Pentti Pirkonen ,  Martina Lille ,  Hannu Mursunen

IPC: D21H11/18 ,  D21C9/18 ,  C08B15/02 ,  D21H15/02

CPC classification number: C08B15/02 ,  D21C9/18 ,  D21H11/18 ,  D21H15/02 ,  Y10T428/2982

Abstract: A method for concentrating fibril cellulose including subjecting aqueous fibril cellulose at a concentration of not higher than 5% to pressure filtration where water is removed from the fibril cellulose by applying pressure to the aqueous fibril cellulose, and continuing the pressure filtration continued to an end point where over 50% of the water initially present is removed from the fibril cellulose. The pressure filtration is performed at a temperature of 30° C. or higher.

公开(公告)号：US09416493B2

公开(公告)日：2016-08-16

申请号：US14378407

申请日：2013-02-12

Applicant: UPM-KYMMENE CORPORATION

Inventor： Kari Hillebrand ,  Markus Nuopponen ,  Martina Lille ,  Juha Tamper

IPC: D21H11/18 ,  D21F1/66 ,  D21F5/00 ,  D21F1/10 ,  D21C9/18 ,  D21H25/04 ,  D21H15/02

CPC classification number: D21H11/18 ,  D21C9/18 ,  D21F1/10 ,  D21F1/66 ,  D21F5/00 ,  D21H15/02 ,  D21H25/04

Abstract: The invention relates to a method for processing chemically modified fibril cellulose. The method includes introducing chemically modified fibril cellulose material to a thermal drying device including a belt in such a way that the fibril cellulose material forms at least one bar onto the belt, and dewatering the chemically modified fibril cellulose material on the belt using heated air flow having a temperature of at least 40 ° C. in order to concentrate and/or dry the chemically modified fibril cellulose material in such a way that the dry solids content of the fibril cellulose material after the thermal drying device is at least 10%. In addition, this invention relates to a thermal drying device, a system for processing chemically modified fibril cellulose, a method and a system for redispersing the fibril cellulose, and a fibril cellulose material.

Abstract translation: 本发明涉及一种加工化学改性的原纤维纤维素的方法。 该方法包括将化学改性的原纤维素材料引入包括带的热干燥装置中，使得原纤维纤维素材料在带上形成至少一个条，并使用加热的空气流使带上的化学改性的原纤维素材料脱水 具有至少40℃的温度以浓缩和/或干燥化学改性的原纤维纤维素材料，使得热干燥装置之后的原纤维纤维素材料的干固体含量至少为10％。 此外，本发明涉及热干燥装置，用于加工化学改性的原纤维纤维的系统，用于再分散原纤维素的方法和系统，以及原纤维纤维素材料。