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    Therapeutic compositions with a cytostatic action containing isocyanuric acid derivatives and process of manufacture
    2.
    发明授权
    Therapeutic compositions with a cytostatic action containing isocyanuric acid derivatives and process of manufacture 失效
    含有异氰脲酸衍生物的细胞生长抑制作用的治疗组合物及其制造方法

    公开(公告)号：US4376120A

    公开(公告)日：1983-03-08

    申请号：US289392

    申请日：1981-08-03

    申请人： Ulrich Zeidler ,  Herbert Fischer ,  Brigitte Hase ,  Hinrich Moller ,  Hans-Christoph Wilk

    发明人： Ulrich Zeidler ,  Herbert Fischer ,  Brigitte Hase ,  Hinrich Moller ,  Hans-Christoph Wilk

    IPC分类号： C07D251/34 ,  A61K31/53

    CPC分类号： C07D251/34

    摘要： New cytostatic compounds based on isocyanuric acid derivatives having 2 or 3 epoxide group containing substituents on ring nitrogen atoms, of which at least one differs from a glycidyl, having the formula ##STR1## wherein Oxiranyl is the same or different and has the formula ##STR2## wherein R.sub.1, R.sub.2 and R.sub.3 are the same or different and members selected from the group consisting of hydrogen, alkyl, haloalkyl, hydroxyalkyl and alkoxyalkyl and n in an integer from 1 to 8, with the proviso that if n is 1 in all oxiranyl groups, at least one of R.sub.1 or R.sub.3 is other than hydrogen, and R is a member selected from the group consisting of oxiranyl as defined above, hydrogen, alkyl, alkenyl, hydrocarbon aryl, hydrocarbon aralkyl, hydrocarbon alkaryl, cycloalkyl, and cycloalkenyl, optionally containing substituents.When R.sub.1, R.sub.2 and/or R.sub.3 denote alkyl or substituted alkyl in the oxiranyl radical, the alkyl radicals preferably have from 1 to 4 carbon atoms. The total number of carbon atoms in one oxiranyl radical should not be more than 10. The preparation of these compounds by introducing oxiranyl groups of Formula II and the radical R in known manner into the isocyanuric acid ring is also claimed.

    摘要翻译： 基于在环氮原子上具有2或3个环氧基团的取代基的异氰脲酸衍生物的新的细胞抑制化合物，其中至少一个不同于缩水甘油基，其具有式（VII），其中环氧乙烷基相同或不同，具有式IMA图 其中R 1，R 2和R 3相同或不同，并且选自氢，烷基，卤代烷基，羟基烷基和烷氧基烷基和n在1至8的整数中的成员，条件是如果在所有环氧乙烷基中n为1 基团，R 1或R 3中的至少一个不是氢，R是选自如上定义的环氧乙烷，氢，烷基，烯基，烃芳基，烃芳烷基，烃烷芳基，环烷基和环烯基的成员， 任选地含有取代基。 当R1，R2和/或R3表示环氧乙烷基中的烷基或取代的烷基时，烷基优选具有1至4个碳原子。 一个环氧乙烷基中碳原子的总数不应大于10.通过将式II的环氧乙烷基和已知方式的基团R引入到异氰脲酸环中，这些化合物的制备也被要求保护。

    Water-dilutable lacquer binders based upon alkyd and acrylate resins
    6.
    发明授权
    Water-dilutable lacquer binders based upon alkyd and acrylate resins 失效
    基于醇酸树脂和丙烯酸酯树脂的水可稀释漆粘合剂

    公开(公告)号：US4451596A

    公开(公告)日：1984-05-29

    申请号：US415067

    申请日：1982-09-07

    申请人： Hans-Christoph Wilk ,  Bernd Wegemund

    发明人： Hans-Christoph Wilk ,  Bernd Wegemund

    IPC分类号： C08L33/00 ,  C08F2/44 ,  C08F283/02 ,  C08L33/02 ,  C08L33/04 ,  C08L67/00 ,  C08L67/08 ,  C09D133/04 ,  C09D151/00 ,  C09D151/08 ,  C09D167/00 ,  C09D167/08 ,  C08L67/06

    CPC分类号： C09D151/08 ,  C08F283/02 ,  C09D167/08

    摘要： This invention is directed to water-dilutable alkyd and acrylate resins. More particularly, this invention is directed to a method for the preparation of water-dilutable resin preparations based upon alkyd and acrylate resins which comprises the steps of:(a) preparing an aqueous alkyd resin dispersion, wherein the alkyd resin has an acid number of from about 5 to 40 and a hydroxyl number of from about 150 to 300 and the dispersion has a solids content of from about 30 to 90 percent by weight; and(b) polymerizing monomers of acrylic acid derivatives or methacrylic acid derivatives in the dispersion from step (a), optionally in the presence of additional water, to obtain a total solids content of from about 30 to 80 percent by weight, the weight ratio of alkyd resin to acrylate resin being from about 1:4 to 9:1.This invention is also directed to the use of these binders in water-dilutable lacquer systems.

    摘要翻译： 本发明涉及水可稀释的醇酸树脂和丙烯酸酯树脂。 更具体地，本发明涉及一种制备基于醇酸树脂和丙烯酸酯树脂的水可稀释树脂制剂的方法，其包括以下步骤：（a）制备醇酸树脂水分散体，其中醇酸树脂的酸值为 约5至40，羟值为约150至300，分散体具有约30至90重量％的固体含量; 和（b）在步骤（a）的分散体中任选地在另外的水的存在下，将丙烯酸衍生物或甲基丙烯酸衍生物的单体聚合，得到约30至80重量％的总固体含量，重量比 的醇酸树脂与丙烯酸酯树脂的比例为约1:4至9:1。 本发明还涉及这些粘合剂在水可稀释漆系统中的用途。

    Polymer dispersions or emulsions as temporary surface protectants
    7.
    发明授权
    Polymer dispersions or emulsions as temporary surface protectants 失效
    聚合物分散体或乳液作为临时表面保护剂

    公开(公告)号：US4476269A

    公开(公告)日：1984-10-09

    申请号：US450185

    申请日：1982-12-15

    申请人： Hans-Christoph Wilk ,  Jurgen Geke

    发明人： Hans-Christoph Wilk ,  Jurgen Geke

    IPC分类号： C09D5/02 ,  B01F17/34 ,  C09D5/00 ,  C09D5/20 ,  C09D157/04 ,  C09D157/06 ,  C08K5/12

    CPC分类号： C09D157/04 ,  C09D157/06 ,  C09D5/008

    摘要： Easily removable protective coatings formed from aqueous dispersions or emulsions of synthetic copolymers that can form a salt and wherein these aqueous coating materials, in addition to water, contain the following constituents:(a) at least one copolymer which:(i) at a temperature of about 5.degree. C. and above will form a film,(ii) contains acid or amino groups wherein the copolymer is water-insoluble therewith, but wherein the copolymer becomes water-soluble when the acid or amino groups are in the form of a salt, and(iii) can exist in the form of an aqueous dispersion or emulsion.(b) at least one water-immiscible non-solvent which:(i) will not dissolve the copolymer in (a),(ii) has low volatility, and(iii) is liquid at room temperature;(c) at least one nonionic emulsifier with an HLB-value of less than 10; and(d) additional adjuvants and/or additives.The invention also relates to the application of these coating materials as temporary surface protectors, especially for metallic and/or painted surfaces, for storage in the open air with exposure to climatic and/or mechanical influences.

    摘要翻译： 由水性分散体或可形成盐的合成共聚物的乳液形成的容易移除的保护涂层，除了水之外，这些含水涂料含有以下组分：（a）至少一种共聚物，其：（i）在温度 约5℃以上将形成膜，（ii）含有酸或氨基，其中共聚物与其不溶于水，但其中当酸或氨基为 盐，和（iii）可以水分散体或乳液的形式存在。 （b）至少一种与水不混溶的非溶剂：（i）不溶于（a）中的共聚物，（ii）具有低挥发性，和（iii）在室温下为液体; （c）HLB值小于10的至少一种非离子乳化剂; 和（d）另外的佐剂和/或添加剂。 本发明还涉及这些涂层材料作为临时表面保护器，特别是金属和/或涂漆表面的应用，用于暴露在气候和/或机械影响下的露天空间中。

    Alkyd resins containing functional epoxides
    8.
    发明授权
    Alkyd resins containing functional epoxides 失效
    含有功能性环氧化物的醇酸树脂

    公开(公告)号：US4474941A

    公开(公告)日：1984-10-02

    申请号：US561626

    申请日：1983-12-15

    申请人： Hans-Christoph Wilk ,  Alfred Meffert ,  Bernd Wegemund

    发明人： Hans-Christoph Wilk ,  Alfred Meffert ,  Bernd Wegemund

    IPC分类号： C08G63/00 ,  C08G63/48 ,  C08G63/78 ,  C09D167/00 ,  C09D167/08 ,  C08G63/54

    CPC分类号： C08G63/48 ,  C09D167/08

    摘要： Alkyd resins containing functional epoxides as long-chain modifying agents. The functional epoxides used are selected from the following:(a) epoxidized unsaturated fatty alcohols containing from 16 to 22 C-atoms,(b) esters of epoxidized fatty acids and monofunctional alcohols containing from 1 to 18 C-atoms,(c) epoxidized triglycerides,(d) reaction products of epoxidized triglycerides containing in the molecule epoxide groups and secondary hydroxyl groups formed by ring opening.The alkyd resins according to the invention are distinguished by particularly good weathering properties.

    摘要翻译： 含有功能性环氧化物的醇酸树脂作为长链改性剂。 所使用的功能性环氧化物选自以下：（a）含有16-22个碳原子的环氧化不饱和脂肪醇，（b）环氧化脂肪酸的酯和含有1至18个碳原子的单官能醇，（c）环氧化 甘油三酸酯，（d）环氧化甘油三酸酯在分子环氧基中的反应产物和由开环形成的仲羟基。 根据本发明的醇酸树脂的特征是特别好的耐候性。

    Telomerization of water-soluble monomers
    10.
    发明授权
    Telomerization of water-soluble monomers 失效
    水溶性单体的凝聚

    公开(公告)号：US4385183A

    公开(公告)日：1983-05-24

    申请号：US270491

    申请日：1981-06-04

    申请人： Rainer Hofer ,  Hans-Christoph Wilk ,  Bernd Wegemund

    发明人： Rainer Hofer ,  Hans-Christoph Wilk ,  Bernd Wegemund

    IPC分类号： C08F2/00 ,  C08F2/16 ,  C08F2/22 ,  C08F2/38 ,  C07C55/22 ,  C07C55/24

    CPC分类号： C08F2/38

    摘要： This invention is directed to the telomerization of water-soluble monomers in an aqueous phase. More particularly, this invention is directed to a process for the telomerization of water-soluble monomers and water-insoluble telogens in aqueous phase, wherein the water-insoluble telogens are solubilized by the addition of an effectively solubilizing amount of surface-active compounds.

    摘要翻译： 本发明涉及在水相中水溶性单体的调聚。 更具体地说，本发明涉及一种在水相中调节水溶性单体和水不溶性前体体的方法，其中通过加入有效溶解量的表面活性化合物来溶解水不溶性的前体药物。