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公开(公告)号:US08895241B2
公开(公告)日:2014-11-25
申请号:US13417035
申请日:2012-03-09
申请人: Urs Ochsner , Evaldas Katilius , Nebojsa Janjic
发明人: Urs Ochsner , Evaldas Katilius , Nebojsa Janjic
IPC分类号: C12Q1/68 , C12N15/115 , C07H21/02 , C07H21/04
CPC分类号: G01N33/573 , C12N15/115 , C12N2310/16 , G01N2333/91102
摘要: The present disclosure relates generally to the field of nucleic acids and, more particularly, to aptamers capable of binding to toxins produced by Clostridium difficile; diagnostic kits and methods comprising such aptamers; and methods of making and using such aptamers.
摘要翻译: 本公开一般涉及核酸领域,更具体地涉及能够结合艰难梭菌产生的毒素的适体; 包括这种适体的诊断试剂盒和方法; 以及制造和使用这些适体的方法。
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公开(公告)号:US20120231467A1
公开(公告)日:2012-09-13
申请号:US13417035
申请日:2012-03-09
申请人: Urs Ochsner , Evaldas Katilius , Nebojsa Janjic
发明人: Urs Ochsner , Evaldas Katilius , Nebojsa Janjic
CPC分类号: G01N33/573 , C12N15/115 , C12N2310/16 , G01N2333/91102
摘要: The present disclosure relates generally to the field of nucleic acids and, more particularly, to aptamers capable of binding to toxins produced by Clostridium difficile; diagnostic kits and methods comprising such aptamers; and methods of making and using such aptamers.
摘要翻译: 本公开一般涉及核酸领域,更具体地涉及能够结合艰难梭菌产生的毒素的适体; 包括这种适体的诊断试剂盒和方法; 以及制备和使用这些适体的方法。
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公开(公告)号:US20080138835A1
公开(公告)日:2008-06-12
申请号:US11568765
申请日:2005-05-09
申请人: Ian A. Critchley , Urs Ochsner , James M. Bullard
发明人: Ian A. Critchley , Urs Ochsner , James M. Bullard
IPC分类号: G01N33/573 , G01N33/566 , C07K14/00
CPC分类号: C12Q1/025 , C12Q1/18 , G01N2333/31
摘要: Mutant bacterial MRS nucleic acids and proteins are provided, as well as uses for the nucleic acids and proteins, such as in a high-throughput screen for inhibitors of the mutant proteins.
摘要翻译: 提供了突变细菌MRS核酸和蛋白质,以及用于核酸和蛋白质的用途,例如在用于突变蛋白质抑制剂的高通量筛选中。
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