Ribosome Display or Mrna Display Method With Selection for Increased Stability of the Protein
    4.
    发明申请
    Ribosome Display or Mrna Display Method With Selection for Increased Stability of the Protein 审中-公开
    核糖体显示或选择增加蛋白质稳定性的Mrna显示方法

    公开(公告)号:US20070298430A1

    公开(公告)日:2007-12-27

    申请号:US11813199

    申请日:2006-01-05

    IPC分类号: C12Q1/68 C07K1/08 C12P21/06

    CPC分类号: C12N15/1062 C12N15/1041

    摘要: A method of providing a subject polypeptide variant with improved stability compared with a parent subject polypeptide, employing translation and selection using an RNA expression system, wherein two or more stability selection pressures are applied simultaneously during translation, two or more stability selection pressures are applied simultaneously during selecting, or at least one stability selection pressure is applied during translation and continues to be applied during selecting, and at least one further stability selection pressure is applied during selecting.

    摘要翻译: 提供与亲本受试者多肽相比具有改善的稳定性的受试者多肽变体的方法,其使用使用RNA表达系统的翻译和选择,其中在翻译期间同时施加两个或更多个稳定性选择压力,同时施加两个或更多稳定性选择压力 或在选择期间施加至少一个稳定性选择压力,并且在选择期间继续施加稳定性选择压力,并且在选择期间施加至少一个其它稳定性选择压力。

    Engineered wood construction system for high performance structures
    5.
    发明授权
    Engineered wood construction system for high performance structures 有权
    用于高性能结构的工程木结构系统

    公开(公告)号:US08935892B2

    公开(公告)日:2015-01-20

    申请号:US13471528

    申请日:2012-05-15

    摘要: A building includes a connection between an engineered wood load bearing element of the building such as a column, beam, or load bearing panel, and another load bearing element or a foundation of the building. At least one tendon ties the load bearing elements or the load bearing element and the foundation together. One or more energy dissipaters, replaceably connected between the load bearing element and/or the foundation, absorb energy when a loading event causes relative movement of the connection. The engineered wood element may be a laminated veneer lumber element, a parallel strand lumber element, or a glue laminated timber element, for example. Typically all of the load bearing elements of the building will be engineered wood elements. The building may be single or multi-storey. The building system enables lightweight low cost buildings, with energy dissipaters which may be replaced after extreme loading. The building may be prefabricated.

    摘要翻译: 建筑物包括建筑物的工程木承载元件之间的连接,例如柱,梁或承载板,以及另一承载元件或建筑物的基础。 至少有一个腱将承载元件或承载元件和基础结合在一起。 当负载事件引起连接的相对运动时,可替代地连接在承载元件和/或基座之间的一个或多个能量消散器吸收能量。 工程木质元件可以是例如层压单板木材元件,平行线木材元件或胶合层压木材元件。 通常,建筑物的所有承载元件都将是木材元素。 建筑物可能是单层或多层。 建筑系统能够实现轻型低成本建筑物,能量消散器可在极限载荷后更换。 建筑物可以预制。

    Engineered Wood Construction System for High Performance Structures
    6.
    发明申请
    Engineered Wood Construction System for High Performance Structures 有权
    高性能结构工程木结构系统

    公开(公告)号:US20130019545A1

    公开(公告)日:2013-01-24

    申请号:US13471528

    申请日:2012-05-15

    IPC分类号: E04B1/98 E04B1/19 E04C5/12

    摘要: A building includes a connection between an engineered wood load bearing element of the building such as a column, beam, or load bearing panel, and another load bearing element or a foundation of the building. At least one tendon ties the load bearing elements or the load bearing element and the foundation together. One or more energy dissipaters, replaceably connected between the load bearing element and/or the foundation, absorb energy when a loading event causes relative movement of the connection. The engineered wood element may be a laminated veneer lumber element, a parallel strand lumber element, or a glue laminated timber element, for example. Typically all of the load bearing elements of the building will be engineered wood elements. The building may be single or multi-storey. The building system enables lightweight low cost buildings, with energy dissipaters which may be replaced after extreme loading. The building may be prefabricated.

    摘要翻译: 建筑物包括建筑物的工程木承载元件之间的连接,例如柱,梁或承载板,以及另一承载元件或建筑物的基础。 至少有一个腱将承载元件或承载元件和基础结合在一起。 当负载事件引起连接的相对运动时,可替代地连接在承载元件和/或基座之间的一个或多个能量消散器吸收能量。 工程木质元件可以是例如层压单板木材元件,平行线木材元件或胶合层压木材元件。 通常,建筑物的所有承载元件都将是木材元素。 建筑物可能是单层或多层。 建筑系统能够实现轻型低成本建筑物,能量消散器可在极限载荷后更换。 建筑物可以预制。

    Methods and means relating to protein variants
    7.
    发明授权
    Methods and means relating to protein variants 有权
    与蛋白质变体相关的方法和手段

    公开(公告)号:US08288123B2

    公开(公告)日:2012-10-16

    申请号:US11326710

    申请日:2006-01-05

    IPC分类号: C12P21/02 C12N5/00

    CPC分类号: C12N15/1062 C12N15/1041

    摘要: A method of providing a subject polypeptide variant with improved stability compared with a parent subject polypeptide, employing translation and selection using an RNA expression system, wherein two or more stability selection pressures are applied simultaneously during translation, two or more stability selection pressures are applied simultaneously during selecting, or at least one stability selection pressure is applied during translation and continues to be applied during selecting, and at least one further stability selection pressure is applied during selecting.

    摘要翻译: 提供与亲本受试者多肽相比具有改善的稳定性的受试者多肽变体的方法,其使用使用RNA表达系统的翻译和选择,其中在翻译期间同时施加两个或更多个稳定性选择压力,同时施加两个或更多稳定性选择压力 或在选择期间施加至少一个稳定性选择压力,并且在选择期间继续施加稳定性选择压力,并且在选择期间施加至少一个其它稳定性选择压力。

    Engineered Wood Construction System for High Performance Structures
    8.
    发明申请
    Engineered Wood Construction System for High Performance Structures 审中-公开
    高性能结构工程木结构系统

    公开(公告)号:US20100186316A1

    公开(公告)日:2010-07-29

    申请号:US12376687

    申请日:2007-08-07

    摘要: A building includes a connection between an engineered wood load bearing element of the building such as a column, beam, or load bearing panel, and another load bearing element or a foundation of the building. At least one tendon ties the load bearing elements or the load bearing element and the foundation together. One or more energy dissipaters, replacably connected between the load bearing element and/or the foundation, absorb energy when a loading event causes relative movement of the connection. The engineered wood element maybe a laminated veneer lumber element, a parallel strand lumber element, or a glue laminated timber element, for example. Typically all of the load bearing elements of the building will be engineered wood elements. The building may be single or multi-storey. The building system enables lightweight low cost buildings, with energy dissipaters which may be replaced after extreme loading. The building may be prefabricated

    摘要翻译: 建筑物包括建筑物的工程木承载元件之间的连接,例如柱,梁或承载板,以及另一承载元件或建筑物的基础。 至少有一个腱将承载元件或承载元件和基础结合在一起。 当负载事件引起连接的相对移动时,一个或多个能量消耗器可替换地连接在承载元件和/或基座之间,从而吸收能量。 工程木质元件可以是例如层压的单板木材元件,平行线木材元件或胶合层压木材元件。 通常,建筑物的所有承载元件都将是木材元素。 建筑物可能是单层或多层。 建筑系统能够实现轻型低成本建筑物,能量消散器可在极限载荷后更换。 建筑物可以预制

    Methods and means relating to protein variants
    10.
    发明申请
    Methods and means relating to protein variants 有权
    与蛋白质变体相关的方法和手段

    公开(公告)号:US20060183200A1

    公开(公告)日:2006-08-17

    申请号:US11326710

    申请日:2006-01-05

    CPC分类号: C12N15/1062 C12N15/1041

    摘要: A method of providing a subject polypeptide variant with improved stability compared with a parent subject polypeptide, employing translation and selection using an RNA expression system, wherein two or more stability selection pressures are applied simultaneously during translation, two or more stability selection pressures are applied simultaneously during selecting, or at least one stability selection pressure is applied during translation and continues to be applied during selecting, and at least one further stability selection pressure is applied during selecting.

    摘要翻译: 提供与亲本受试者多肽相比具有改善的稳定性的受试者多肽变体的方法,其使用使用RNA表达系统的翻译和选择,其中在翻译期间同时施加两个或更多个稳定性选择压力,同时施加两个或更多稳定性选择压力 或在选择期间施加至少一个稳定性选择压力,并且在选择期间继续施加稳定性选择压力,并且在选择期间施加至少一个其它稳定性选择压力。