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21 条记录 (耗时 0.029 秒)

    Micro scale mechanical rate sensors
    1.
    发明授权
    Micro scale mechanical rate sensors 失效
    微型机械速率传感器

    公开(公告)号：US08479574B2

    公开(公告)日：2013-07-09

    申请号：US12871912

    申请日：2010-08-31

    申请人： Viacheslav Krylov ,  David Schreiber ,  Yosi Shacham-Diamand

    发明人： Viacheslav Krylov ,  David Schreiber ,  Yosi Shacham-Diamand

    IPC分类号： G01C19/56

    CPC分类号： G01C19/56 ,  Y10T29/49826

    摘要： An angular rate sensor device is presented. The sensor device comprises a disk-shaped structure having a proof mass region and a flexible portion. The disk-like structure is coupled to a substrate in a manner enabling a wave type precession motion such that during the wave type precession motion each material point of the proof mass performs elliptic motion.

    摘要翻译： 提出了一种角速率传感器装置。 传感器装置包括具有检验质量区域和柔性部分的盘形结构。 盘状结构以能够进行波型进动运动的方式耦合到基板，使得在波型进动运动期间，证明块的每个材料点执行椭圆运动。

    Methods of detecting cancer cells and use of same for diagnosing and monitoring treatment of the disease
    2.
    发明申请
    Methods of detecting cancer cells and use of same for diagnosing and monitoring treatment of the disease 失效
    检测癌细胞的方法及其用途，用于诊断和监测疾病的治疗

    公开(公告)号：US20090232740A1

    公开(公告)日：2009-09-17

    申请号：US12379974

    申请日：2009-03-05

    申请人： Judith Rishpon ,  Rachela Popovtzer ,  Yosi Shacham-Diamand ,  Tova Neufeld ,  Sefi Vernick

    发明人： Judith Rishpon ,  Rachela Popovtzer ,  Yosi Shacham-Diamand ,  Tova Neufeld ,  Sefi Vernick

    IPC分类号： A61K49/00 ,  G01N33/574 ,  A61P35/00

    CPC分类号： G01N33/5011 ,  C12Q1/42

    摘要： A method of detecting cancer cells is disclosed. The method comprises (a) contacting the cell with a substrate for an enzyme under conditions wherein the enzyme catalyzes a reaction of the cell with said substrate, so as to generate a product capable of producing an electrical signal; and (b) measuring a level of the electrical signal, wherein a difference in a level of said electrical signal compared to a predetermined threshold is indicative of a cancer cell. The method may be adapted for diagnosis, monitoring a cancer therapy, identifying agents capable of treating cancer and individually optimizing a cancer therapy.

    摘要翻译： 公开了一种检测癌细胞的方法。 该方法包括（a）在酶催化细胞与所述底物的反应的条件下，使细胞与酶底物接触，从而产生能产生电信号的产物; 和（b）测量电信号的电平，其中所述电信号的电平差与预定阈值相比指示癌细胞。 该方法可适用于诊断，监测癌症治疗，鉴定能够治疗癌症并单独优化癌症治疗的药剂。

    Electroless deposition of metal films with spray processor
    5.
    发明授权
    Electroless deposition of metal films with spray processor 失效
    用喷雾处理器无电沉积金属膜

    公开(公告)号：US6065424A

    公开(公告)日：2000-05-23

    申请号：US768447

    申请日：1996-12-18

    申请人： Yosi Shacham-Diamand ,  Vinh Nguyen ,  Valery Dubin

    发明人： Yosi Shacham-Diamand ,  Vinh Nguyen ,  Valery Dubin

    IPC分类号： C23C18/31 ,  C23C18/16 ,  C23C18/32 ,  C23C18/38 ,  C23C18/40 ,  C23C18/44 ,  H01L21/288 ,  B05C5/00

    CPC分类号： C23C18/405 ,  C23C18/1619 ,  C23C18/1658 ,  C23C18/166 ,  C23C18/1676 ,  C23C18/1682 ,  C23C18/1692

    摘要： Electroless plating of very thin metal films, such as copper, is accomplished with a spray processor. Atomized droplets or a continuous stream of an electroless plating solution are sprayed on a substrate. The electroless plating solution may be prepared by mixing a reducing solution and a metal stock solution immediately prior to the spraying. The deposition process may be carried out in an apparatus which includes metal stock solution and reducing reservoirs, a mixing chamber for forming the plating solution, optionally an inert gas or air (oxygen) source, a process chamber in which the solution is sprayed on the substrate and a control system for providing solutions to the mixing chamber and the process chamber in accordance with a predetermined program for automated mixing and spraying of the plating solution. The process can be used to form metal films as thin as 100 .ANG. and these films have low resistivity values approaching bulk values, low surface roughness, excellent electrical and thickness uniformity and mirror-like surface. Low temperature annealing may be used to further improve electrical characteristics of the deposited films. The thin metal films produced by the disclosed process can be used in semiconductor wafer fabrication and assembly, and in preparation of thin film discs, thin film heads, optical storage devices, sensor devices, microelectromachined sensors (MEMS) and actuators, and optical filters.

    摘要翻译： 使用喷雾处理器实现非常薄的金属膜（例如铜）的无电镀。 将雾化的液滴或连续的无电镀液流喷射到基底上。 化学镀溶液可以通过在喷雾之前立即混合还原溶液和金属储备溶液来制备。 沉积过程可以在包括金属储备溶液和还原储存器的设备，用于形成电镀溶液的混合室，任选的惰性气体或空气（氧）源），其中溶液喷洒在其上的处理室 基板和用于根据用于电镀液的自动混合和喷涂的预定程序向混合室和处理室提供溶液的控制系统。 该方法可用于形成薄至100的金属膜，并且这些膜具有接近体积值，低表面粗糙度，优异的电和厚度均匀性以及镜面状表面的低电阻率值。 可以使用低温退火来进一步改善沉积膜的电特性。 通过所公开的方法制造的薄金属膜可用于半导体晶片制造和组装，以及薄膜盘，薄膜头，光学存储装置，传感器装置，微机电传感器（MEMS）和致动器以及光学滤波器的制备中。

    Electrochemical methods of detecting cancer with 4-aminophenyl phosphate
    6.
    发明授权
    Electrochemical methods of detecting cancer with 4-aminophenyl phosphate 失效
    用4-氨基苯基磷酸酯检测癌症的电化学方法

    公开(公告)号：US08530179B2

    公开(公告)日：2013-09-10

    申请号：US13551642

    申请日：2012-07-18

    申请人： Judith Rishpon ,  Rachela Popovtzer ,  Yosi Shacham-Diamand ,  Tova Neufeld ,  Sefi Vernick

    发明人： Judith Rishpon ,  Rachela Popovtzer ,  Yosi Shacham-Diamand ,  Tova Neufeld ,  Sefi Vernick

    IPC分类号： C12Q1/42

    CPC分类号： G01N33/5011 ,  C12Q1/42

    摘要： A method of detecting cancer cells is disclosed. The method comprises (a) contacting the cell which is suspicious of a cancerous or undifferentiated phenotype with 4-aminophenyl phosphate (p-APP) under conditions wherein alkaline phosphatase of the cell catalyzes a reaction of the cell with the p-APP, so as to generate a product capable of producing an electrical signal; and (b) measuring a level of the electrical signal, wherein a difference in a level of the electrical signal compared to a predetermined threshold is indicative of a cancer cell.

    摘要翻译： 公开了一种检测癌细胞的方法。 该方法包括（a）在细胞的碱性磷酸酶催化细胞与p-APP的反应的条件下，将可疑癌症或未分化表型的细胞与4-氨基苯基磷酸（p-APP）接触，以便 以产生能够产生电信号的产品; 和（b）测量电信号的电平，其中与预定阈值相比较的电信号电平的差异指示癌细胞。

    Biologically active metal-coated proteins
    7.
    发明申请
    Biologically active metal-coated proteins 审中-公开
    生物活性金属包被的蛋白质

    公开(公告)号：US20090127112A1

    公开(公告)日：2009-05-21

    申请号：US11920689

    申请日：2006-05-18

    申请人： Amihay Freeman ,  Yosi Shacham-Diamand ,  Sefi Vernick ,  Hila Moscovich-Dagan

    发明人： Amihay Freeman ,  Yosi Shacham-Diamand ,  Sefi Vernick ,  Hila Moscovich-Dagan

    IPC分类号： G01N33/487 ,  C12N9/04 ,  A61K9/00 ,  A61K38/44

    CPC分类号： G01N33/54373 ,  A61B5/1486 ,  G01N33/532 ,  G01N33/68 ,  G01N33/84 ,  Y10T428/12493

    摘要： Metal-coated proteins, being dissolvable or suspendable in aqueous media and/or retaining a biological activity of the protein, a process and intermediates for preparing same are disclosed. Further disclosed are a pharmaceutical composition containing and a method of treating bacterial and fungal infections utilizing biologically active metal-coated proteins. Conductive elements, electronic circuits containing same, electrodes and biosensor systems utilizing same, and imaging probes, all containing the metal-coated proteins, are also disclosed.

    摘要翻译： 公开了金属包覆的蛋白质，其可溶于或悬浮于水性介质中和/或保留蛋白质的生物活性，制备方法和中间体。 还公开了一种药物组合物，其含有利用生物活性金属包被的蛋白质治疗细菌和真菌感染的方法。 还公开了导电元件，含有它们的电子电路，使用它们的电极和生物传感器系统，以及全部含有金属包被的蛋白质的成像探针。