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1.Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders 有权
标题翻译: 可用于治疗肿瘤性疾病,炎症性疾病和免疫调节性疾病的三环类化合物衍生物公开(公告)号:US20080171769A1
公开(公告)日:2008-07-17
申请号:US11891604
申请日:2007-08-10
申请人: Vlad E. Gregor , Yahua Liu , Alexey Anikin , Danny Peter Claude McGee , Charles Mikel , Douglas Eric McGrath , Goverdhan Reddy Vavilala , Jason C. Pickens , Alexander Kadushkin , Luyong Jiang , Mohan Santhanam Thiruvazhi , Sergey Zozulya , Rajendran Vairagoundar , Tong Zhu , Alexander Chucholowski , Thomas Webb , Vidyasagar Reddy Gantla , Zheng Yan
发明人: Vlad E. Gregor , Yahua Liu , Alexey Anikin , Danny Peter Claude McGee , Charles Mikel , Douglas Eric McGrath , Goverdhan Reddy Vavilala , Jason C. Pickens , Alexander Kadushkin , Luyong Jiang , Mohan Santhanam Thiruvazhi , Sergey Zozulya , Rajendran Vairagoundar , Tong Zhu , Alexander Chucholowski , Thomas Webb , Vidyasagar Reddy Gantla , Zheng Yan
IPC分类号: A61K31/444 , C07D401/14 , C12N9/99 , A61P3/10 , A61P9/10 , A61P35/00 , A61K31/4439
CPC分类号: C07D487/04
摘要: Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.
摘要翻译: 提供式(I)化合物或其调节酪氨酸激酶活性的立体异构体,互变异构体,盐,水合物或前药,包含化合物的组合物及其使用方法。
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2.Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders 有权
标题翻译: 可用于治疗肿瘤性疾病,炎症性疾病和免疫调节性疾病的三环类化合物衍生物公开(公告)号:US08063225B2
公开(公告)日:2011-11-22
申请号:US11891604
申请日:2007-08-10
申请人: Vlad E. Gregor , Yahua Liu , Alexey Anikin , Danny Peter Claude McGee , Charles Mikel , Douglas Eric McGrath , Goverdhan Reddy Vavilala , Jason C. Pickens , Alexander Kadushkin , Luyong Jiang , Mohan Santhanam Thiruvazhi , Sergey Zozulya , Rajendran Vairagoundar , Tong Zhu , Alexander Chucholowski , Thomas Webb , Vidyasagar Reddy Gantla , Zheng Yan
发明人: Vlad E. Gregor , Yahua Liu , Alexey Anikin , Danny Peter Claude McGee , Charles Mikel , Douglas Eric McGrath , Goverdhan Reddy Vavilala , Jason C. Pickens , Alexander Kadushkin , Luyong Jiang , Mohan Santhanam Thiruvazhi , Sergey Zozulya , Rajendran Vairagoundar , Tong Zhu , Alexander Chucholowski , Thomas Webb , Vidyasagar Reddy Gantla , Zheng Yan
IPC分类号: C07D401/00 , A61K31/44
CPC分类号: C07D487/04
摘要: Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.
摘要翻译: 提供式(I)化合物或其调节酪氨酸激酶活性的立体异构体,互变异构体,盐,水合物或前药,包含该化合物的组合物及其使用方法。
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