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公开(公告)号：US08012507B2
公开(公告)日：2011-09-06
申请号：US11978949
申请日：2007-10-29
Applicant: Vu Truong-Le , Binh Pham
Inventor： Vu Truong-Le , Binh Pham
CPC classification number: A61K9/1629 , A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/1658 , A61K9/1694 , A61K35/76 , C12N2760/16251 , F26B3/12
Abstract: This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials.
Abstract translation: 本发明提供了在粉末颗粒基质中保存生物活性材料的方法和组合物。 方法提供高压气体喷雾和/或接近超临界喷雾制剂，然后在调节气体流中干燥以形成含有生物活性材料的稳定的粉末颗粒。
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公开(公告)号：US07700130B2
公开(公告)日：2010-04-20
申请号：US11809662
申请日：2007-05-31
Applicant: Vu Truong-Le , Binh Pham
Inventor： Vu Truong-Le , Binh Pham
IPC: A61K9/14
CPC classification number: A61K9/1629 , A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/1658 , A61K9/1694 , A61K35/76 , C12N2760/16251 , F26B3/12
Abstract: This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials.
Abstract translation: 本发明提供了在粉末颗粒基质中保存生物活性材料的方法和组合物。 方法提供高压气体喷雾和/或接近超临界喷雾制剂，然后在调节气体流中干燥以形成含有生物活性材料的稳定的粉末颗粒。
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公开(公告)号：US20100331428A1
公开(公告)日：2010-12-30
申请号：US12266493
申请日：2008-11-06
Applicant: Vu Truong-Le , Satoshi Ohtake , Russell Andrew Martin , Binh Pham , Luisa Yee
Inventor： Vu Truong-Le , Satoshi Ohtake , Russell Andrew Martin , Binh Pham , Luisa Yee
CPC classification number: B01D1/18
Abstract: This invention provides methods of spray drying pharmaceutical powders from a vibrating nozzle at low pressures. The method can effectively spray dry thick or viscous solutions or suspensions to provide small uniform particles. The invention includes dry particle compositions prepared by methods of low pressure spraying from vibrating nozzles.
Abstract translation: 本发明提供了在低压下从振动喷嘴喷雾干燥药物粉末的方法。 该方法可以有效地喷洒干燥的稠粘或粘稠溶液或悬浮液以提供小的均匀颗粒。 本发明包括通过从振动喷嘴进行低压喷射的方法制备的干燥颗粒组合物。
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公开(公告)号：US20080131514A1
公开(公告)日：2008-06-05
申请号：US11978949
申请日：2007-10-29
Applicant: Vu Truong-Le , Binh Pham
Inventor： Vu Truong-Le , Binh Pham
CPC classification number: A61K9/1629 , A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/1658 , A61K9/1694 , A61K35/76 , C12N2760/16251 , F26B3/12
Abstract: This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials.
Abstract translation: 本发明提供了在粉末颗粒基质中保存生物活性材料的方法和组合物。 方法提供高压气体喷雾和/或接近超临界喷雾制剂，然后在调节气体流中干燥以形成含有生物活性材料的稳定的粉末颗粒。
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公开(公告)号：US20070259334A1
公开(公告)日：2007-11-08
申请号：US11809662
申请日：2007-05-31
Applicant: Vu Truong-Le , Binh Pham
Inventor： Vu Truong-Le , Binh Pham
CPC classification number: A61K9/1629 , A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/1658 , A61K9/1694 , A61K35/76 , C12N2760/16251 , F26B3/12
Abstract: This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials.
Abstract translation: 本发明提供了在粉末颗粒基质中保存生物活性材料的方法和组合物。 方法提供高压气体喷雾和/或接近超临界喷雾制剂，然后在调节气体流中干燥以形成含有生物活性材料的稳定的粉末颗粒。
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6.发明授权
公开(公告)号：US09539233B2
公开(公告)日：2017-01-10
申请号：US12772854
申请日：2010-05-03
Applicant: Satoshi Ohtake , Vu Truong-Le , David Lechuga-Ballesteros , Luisa Yee , Binh Pham , Russell Martin , Atul Saxena
Inventor： Satoshi Ohtake , Vu Truong-Le , David Lechuga-Ballesteros , Luisa Yee , Binh Pham , Russell Martin , Atul Saxena
CPC classification number: A61K31/28 , A61K9/0078 , A61K9/08 , A61K9/14 , A61K9/1617 , A61K9/1623 , A61K33/24 , A61K47/12 , Y02A50/473 , Y10T428/2982
Abstract: A method and composition for treatment of bacterial infections caused by gram negative or gram positive bacteria such as Staphylococcus aureus, Rhodococcus equi, Mycobacterium tuberculosis, Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug resistant Pseudomonas aeruginosa, using a formulation containing gallium (III), in a pharmaceutically acceptable salt or complex thereof.
Abstract translation: 用于治疗由革兰氏阴性或革兰氏阳性细菌如金黄色葡萄球菌，马氏体球菌，结核分枝杆菌，大肠杆菌，肺炎克雷伯菌，克雷伯杆菌，铜绿假单胞菌，流感嗜血杆菌，奇异变形杆菌，肠杆菌属，沙雷氏菌属引起的细菌感染的方法和组合物 粘膜结肠炎以及由伯克霍克伯克伯克霍尔德氏菌，嗜麦芽寡养单胞菌，产碱杆菌xylosoxidans和多药耐药铜绿假单胞菌引起的那些，其使用含有镓（III）的制剂在其药学上可接受的盐或复合物中。
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公开(公告)号：US08273374B2
公开(公告)日：2012-09-25
申请号：US13194404
申请日：2011-07-29
Applicant: Vu Truong-Le , Binh Pham
Inventor： Vu Truong-Le , Binh Pham
CPC classification number: A61K9/1629 , A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/1658 , A61K9/1694 , A61K35/76 , C12N2760/16251 , F26B3/12
Abstract: This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials.
Abstract translation: 本发明提供了在粉末颗粒基质中保存生物活性材料的方法和组合物。 方法提供高压气体喷雾和/或接近超临界喷雾制剂，然后在调节气体流中干燥以形成含有生物活性材料的稳定的粉末颗粒。
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公开(公告)号：US20120009248A1
公开(公告)日：2012-01-12
申请号：US13194404
申请日：2011-07-29
Applicant: Vu Truong-Le , Binh Pham
Inventor： Vu Truong-Le , Binh Pham
IPC: A61K9/127 , A61K31/7088 , A61K35/74 , A61K35/66 , A61P37/04 , A61K38/43 , A61K39/00 , A61K35/16 , A61K35/76 , A61K9/14 , A61K38/00 , A61K39/395
CPC classification number: A61K9/1629 , A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/1658 , A61K9/1694 , A61K35/76 , C12N2760/16251 , F26B3/12
Abstract: This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials.
Abstract translation: 本发明提供了在粉末颗粒基质中保存生物活性材料的方法和组合物。 方法提供高压气体喷雾和/或接近超临界喷雾制剂，然后在调节气体流中干燥以形成含有生物活性材料的稳定的粉末颗粒。
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公开(公告)号：US07258873B2
公开(公告)日：2007-08-21
申请号：US10412651
申请日：2003-04-10
Applicant: Vu Truong-Le , Binh Pham
Inventor： Vu Truong-Le , Binh Pham
IPC: A61K9/14
CPC classification number: A61K9/1629 , A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/1658 , A61K9/1694 , A61K35/76 , C12N2760/16251 , F26B3/12
Abstract: This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials.
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公开(公告)号：US20190303162A1
公开(公告)日：2019-10-03
申请号：US15940408
申请日：2018-03-29
Applicant: Christopher Wilkerson , Binh Pham , Patrick Lu , Jared Warner Stark, IV
Inventor： Christopher Wilkerson , Binh Pham , Patrick Lu , Jared Warner Stark, IV
Abstract: In an embodiment, a processor includes a branch prediction circuit and a plurality of processing engines. The branch prediction circuit is to: detect a coherence operation associated with a first memory address; identify a first branch instruction associated with the first memory address; and predict a direction for the identified branch instruction based on the detected coherence operation. Other embodiments are described and claimed.
