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公开(公告)号:US20080213366A1
公开(公告)日:2008-09-04
申请号:US11912833
申请日:2006-04-27
CPC分类号: A61K47/10 , A61K9/1617 , A61K9/1652 , A61K9/2013 , A61K9/2081 , A61K9/2866 , A61K31/407 , A61K31/545 , A61K31/546 , A61K38/164
摘要: The present invention provides oral formulations of poorly bioavailable and/or poorly absorbable, and/or poorly water soluble therapeutic agents. The invention features pharmaceutical composition including a biopolymer, a therapeutic agent, for example an antimicrobial agent such as ceftriaxone, and an absorption enhancer, for example a polyoxyethylene alkyl ether absorption enhancer. Methods of making and using the pharmaceutical compositions is also described.
摘要翻译: 本发明提供了不良生物可利用和/或难吸收的和/或水溶性差的治疗剂的口服制剂。 本发明的特征在于药物组合物,其包括生物聚合物,治疗剂,例如抗微生物剂如头孢曲松,和吸收增强剂,例如聚氧乙烯烷基醚吸收增强剂。 还描述了制备和使用药物组合物的方法。