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    Sterile formed, filled and sealed flexible container and draining administration port therefor
    4.
    发明授权
    Sterile formed, filled and sealed flexible container and draining administration port therefor 失效
    无菌形成，填充密封的柔性容器和排水管理端口

    公开(公告)号：US06280431B1

    公开(公告)日：2001-08-28

    申请号：US09178323

    申请日：1998-10-23

    申请人： John Domkowski ,  Ron Coules ,  Peter Carveth ,  Walter T. Szempruch ,  Kent D. Abrahamson

    发明人： John Domkowski ,  Ron Coules ,  Peter Carveth ,  Walter T. Szempruch ,  Kent D. Abrahamson

    IPC分类号： A61B1900

    CPC分类号： A61J1/10 ,  A61J1/1406 ,  Y10S604/905

    摘要： A formed, filled, and sealed flexible container is provided with an attached port assembly. The container is formed from film folded to define opposing sidewalls which are sealed to define a chamber for sterile fluid. A hollow, tubular port member is provided with a V-shaped saddle and is sealed to the bottom of the container. The film at the bottom of the container is received in the saddle. A unique shoulder is defined by the tubular port member. The film is sealed to the shoulder and to the saddle of the port member. A hollow penetrator element is slidably disposed within the port member and is movable between a retracted position and an advanced position to puncture the film whereby fluid can flow out of the container. Internal formations are provided to guide and to limit the movement of the penetrator element. The container film may be provided with a crease along the bottom of the container.

    摘要翻译： 形成的，填充的和密封的柔性容器设置有附接的端口组件。 容器由薄膜折叠形成以限定相对的侧壁，其被密封以限定用于无菌流体的室。 中空的管状端口构件设置有V形鞍座并且密封到容器的底部。 容器底部的胶片被接收在鞍座中。 独特的肩部由管状端口构件限定。 胶片被密封到肩部和端口构件的鞍座上。 中空穿透元件可滑动地设置在端口构件内并且可在缩回位置和前进位置之间移动以刺穿膜，由此流体可以流出容器。 提供内部结构以引导和限制穿透元件的运动。 容器膜可以沿着容器的底部设置有折痕。

    Tamper evidence feature for sterile port and cap system
    6.
    发明授权
    Tamper evidence feature for sterile port and cap system 失效
    无菌口罩和帽系统的篡改证据

    公开(公告)号：US5755712A

    公开(公告)日：1998-05-26

    申请号：US361416

    申请日：1994-12-22

    申请人： Walter T. Szempruch ,  Victor M. Trentadue ,  Stephen C. Yeaton

    发明人： Walter T. Szempruch ,  Victor M. Trentadue ,  Stephen C. Yeaton

    IPC分类号： A61J1/05 ,  A61J1/10 ,  A61B19/00 ,  A65D41/10

    CPC分类号： A61J1/10 ,  Y10S206/807 ,  Y10S215/03 ,  Y10S215/901

    摘要： A port and cap assembly for a solution container is provided. The port includes a tubular wall having a first end and second end, the first end securable to the container and the second end being open and opposite to the first end. An annular flange extends perpendicularly outward from the cylindrical wall between the first end and the second end to define a neck portion of the cylindrical wall. A circumferential sleeve extends longitudinally downward from the annular flange. A radial lip extends generally perpendicularly inward from the sleeve. A resilient cap is also provided which includes a first portion resiliently stretched to cover the open end of the port and a second portion removably captured between the annular flange and the radial lip. The second portion of the cap after being removed from between the annular flange and the radial lip is not recapturable between the annular flange and the radial lip so as to indicate that the port has been uncovered. A method for assembling a port and cap to a solution container is also provided.

    摘要翻译： 提供了用于溶液容器的端口和盖组件。 该端口包括具有第一端和第二端的管状壁，第一端可固定到容器，第二端开放并与第一端相对。 环形凸缘在第一端和第二端之间从圆柱形壁垂直向外延伸，以限定圆柱形壁的颈部。 周向套筒从环形凸缘纵向向下延伸。 径向唇部大致垂直地从套筒向内延伸。 还提供了弹性盖，其包括弹性拉伸以覆盖端口的开口端的第一部分和可拆卸地捕获在环形凸缘和径向唇缘之间的第二部分。 在从环形凸缘和径向唇缘之间移除之后，盖子的第二部分不能在环形凸缘和径向唇缘之间重新适配，以便指示该端口已经未被覆盖。 还提供了将端口和盖子组装到溶液容器的方法。

    Solution pumping system including disposable pump cassette
    7.
    发明授权
    Solution pumping system including disposable pump cassette 失效
    解决方案泵系统包括一次性泵盒

    公开(公告)号：US5062774A

    公开(公告)日：1991-11-05

    申请号：US444459

    申请日：1989-12-01

    申请人： David E. Kramer ,  Andrew J. Muetterties ,  Walter T. Szempruch

    发明人： David E. Kramer ,  Andrew J. Muetterties ,  Walter T. Szempruch

    IPC分类号： A61J3/00 ,  A61M39/22 ,  F04B7/00 ,  F04B11/00 ,  F04B43/02

    CPC分类号： A61J3/002 ,  A61M39/22 ,  F04B11/0041 ,  F04B43/021 ,  F04B7/0076 ,  A61M2205/128 ,  Y10S128/12

    摘要： A solution pumping system including a disposable pump cassette is disclosed, with the system configured for efficient and accurate preparation of parenteral admisture solutions. The system includes a pump driver having a reciprocable pump plunger and a plurality of associated valve actuators. The disposable pump cassette of the system is configured for removable positioning in operative association with the pump driver, and includes a positive displacement pump configured for operation by the reciprocable pump plunger. The pump cassette further includes a plurality of liquid inlets, and at least one liquid outlet joined in fluid communication with the inlets. By selective operation of the valve actuators of the pump driver, one or more selected source solutions are drawn through the pump inlets by the positive displacement pump, and directed through the pump outlet to an admixture solution container. Preferred features of the present pump cassette facilitate liquid flushing to avoid mixture of incompatible source solutions, and enhance the sealing integrity of the cassette construction.

    摘要翻译： 公开了一种包括一次性泵盒的溶液泵送系统，其中该系统被配置为有效和准确地制备肠胃外吸收溶液。 该系统包括具有往复式泵柱塞和多个相关联的阀致动器的泵驱动器。 系统的一次性泵盒被构造成与泵驱动器可操作地关联的可移动定位，并且包括构造成由往复泵柱塞操作的容积式泵。 泵盒还包括多个液体入口，以及与入口流体连通的至少一个液体出口。 通过泵驱动器的阀致动器的选择性操作，通过正排量泵将一个或多个选定的源解决方​​案通过泵入口抽吸，并通过泵出口引导到混合溶液容器。 本泵盒的优选特征便于液体冲洗以避免不相容的源溶液的混合，并提高盒结构的密封完整性。

    Flexible container
    8.
    发明授权
    Flexible container 失效
    柔性容器

    公开(公告)号：US4722727A

    公开(公告)日：1988-02-02

    申请号：US890782

    申请日：1986-07-23

    申请人： John E. Ogden ,  Edward S. Tripp ,  Walter T. Szempruch

    发明人： John E. Ogden ,  Edward S. Tripp ,  Walter T. Szempruch

    IPC分类号： A61J1/05 ,  A61J1/10 ,  A61M1/28 ,  A61M39/22 ,  A61M1/00

    CPC分类号： A61J1/10 ,  A61M39/221 ,  A61M1/28

    摘要： A plug is provided within a port in a flexible container. Extending from the port is a piece of flexible tubing which is used to connect with other tubing in a fluid system. Fluid is dispensed from the flexible container by grasping the end of the plug extending into the flexible container. The plug is then pulled into the interior of the container so that the opposite end of the plug which seals the flexible tubing extending from the port is unseated. The flexible tubing extending from the port is now open to the flow of fluid from the flexible container.

    摘要翻译： 在柔性容器中的端口内提供插头。 从港口延伸的是一条柔性管道，用于与流体系统中的其他管道连接。 通过抓住插入柔性容器的插头的端部，从柔性容器分配流体。 然后将塞子拉入容器的内部，使得密封从端口延伸的柔性管道的塞子的相对端被松开。 从端口延伸的柔性管现在对来自柔性容器的流体流开放。