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公开(公告)号:US20050215580A1
公开(公告)日:2005-09-29
申请号:US11042474
申请日:2005-01-24
申请人: Weibo Wang , Zhi-Jie Ni , Paul Barsanti , Sabina Pecchi , Yi Xia , Nathan Brammeier , Megan Phillips , Elisa Jazan , Kelly Wayman , David Dibble , Jie-Kai Cheng
发明人: Weibo Wang , Zhi-Jie Ni , Paul Barsanti , Sabina Pecchi , Yi Xia , Nathan Brammeier , Megan Phillips , Elisa Jazan , Kelly Wayman , David Dibble , Jie-Kai Cheng
IPC分类号: A61K31/4745 , C07D471/02 , C07D471/04
CPC分类号: C07D471/04
摘要: Tetrahydrocarboline compounds, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the tetrahydrocarboline compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the tetrahydrocarboline compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases.
摘要翻译: 四氢咔啉化合物,其药学上可接受的盐和前药; 包括药学上可接受的载体和一种或多种四氢咔啉化合物的组合物,单独或与至少一种另外的治疗剂组合。 单独使用四氢咔啉化合物或与至少一种另外的治疗剂组合使用的方法可用于预防或治疗增殖性疾病。
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公开(公告)号:US07855295B2
公开(公告)日:2010-12-21
申请号:US11042474
申请日:2005-01-24
申请人: Weibo Wang , Zhi-Jie Ni , Paul Barsanti , Sabina Pecchi , Yi Xia , Nathan Brammeier , Megan C. Phillips , Eliza Jazan , Kelly Wayman , David Dibble , Jie-Kai Cheng
发明人: Weibo Wang , Zhi-Jie Ni , Paul Barsanti , Sabina Pecchi , Yi Xia , Nathan Brammeier , Megan C. Phillips , Eliza Jazan , Kelly Wayman , David Dibble , Jie-Kai Cheng
IPC分类号: A61K31/437 , C07D487/04
CPC分类号: C07D471/04
摘要: Tetrahydrocarboline compounds, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the tetrahydrocarboline compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the tetrahydrocarboline compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases.
摘要翻译: 四氢咔啉化合物,其药学上可接受的盐和前药; 包括药学上可接受的载体和一种或多种四氢咔啉化合物的组合物,单独或与至少一种另外的治疗剂组合。 单独使用四氢咔啉化合物或与至少一种另外的治疗剂组合使用的方法可用于预防或治疗增殖性疾病。
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