公开(公告)号：US5917184A

公开(公告)日：1999-06-29

申请号：US797088

申请日：1997-02-07

申请人： William W. Carson ,  Stephen C. Gabeler ,  Yin Liang F. Hsieh ,  Stephen A. Martin ,  Michael J. Tomany ,  Anotoli Verentchikov

发明人： William W. Carson ,  Stephen C. Gabeler ,  Yin Liang F. Hsieh ,  Stephen A. Martin ,  Michael J. Tomany ,  Anotoli Verentchikov

IPC分类号： H01J49/04 ,  H01J49/10

CPC分类号： H01J49/044 ,  H01J49/165

摘要： An interface apparatus for introducing a sample for analysis from a liquid flow into a mass spectrometer as a plurality of charged droplets is disclosed. The interface apparatus includes interface body which defines a spray chamber and an orifice, a spray means defining a liquid-flow inlet channel and an excess-sample-flow exit channel and having an open end disposed inside the spray chamber, and a voltage device for applying a voltage to the sample to form a plurality of charged droplets. The charged droplets pass through the orifice in the interface body and are introduced into a mass spectrometer for analysis. The interface includes a valve for regulating the flow of sample into the sample inlet channel and a device for imposing a pressure gradient on the sample at the open end which induces the sample to flow from the sample inlet channel through the excess sample outlet channel.

摘要翻译： 公开了一种用于将用于分析的样品从液体流引入质谱仪作为多个带电液滴的界面装置。 接口装置包括限定喷雾室和孔口的界面体，限定液流入口通道的喷射装置和多余样品流出口通道，并且具有设置在喷雾室内部的开口端;以及电压装置， 向样品施加电压以形成多个带电液滴。 带电液滴通过界面体中的孔口，并引入质谱仪进行分析。 该界面包括用于调节样品流入样品入口通道的阀和用于在开口端施加样品上的压力梯度的装置，其引起样品从样品入口通道流过多余的样品出口通道。