公开(公告)号：US20240353430A1

公开(公告)日：2024-10-24

申请号：US18640521

申请日：2024-04-19

Applicant: Worcester Polytechnic Institute

Inventor： Kathryn Woodland ,  Madison Gass ,  Isabel Nearing ,  Grace Jolin ,  Ziya Isiksacan ,  Mathias Bonmarin ,  Sakthikumar Ambady ,  O. Berk Usta ,  Ahmet C. Sabuncu

IPC: G01N33/72 ,  G01N21/78

CPC classification number: G01N33/726 ,  G01N21/78

Abstract: A storage and monitoring device for red blood samples in storage for donation (blood bank) and research. Stored blood can be susceptible to degradation, most often from a phenomenon known as ice nucleation. Accurate detection and identification of relevant factors causing ice nucleation can determine healthy samples of stored blood, and identify storage factors that promote storage longevity. A photodetection approach directs an illumination source and photometer on opposed sides of a blood containing vessel for measuring an illuminance affected by hemoglobin released from ruptured cells. Hemoglobin released from ruptured cells reduces light passage though the sample to indicate unusable samples. An accelerometer and temperature sensor measure the physical and temperate factors correlating with the detected cell degradation to determine storage criteria for extending blood longevity.