摘要:
The invention relates generally to naphthyridine derivatives of the formula wherein one of U, X, Y and Z is nitrogen and the others are C—R, where R is hydrogen or a substituent. More specifically, the invention relates to 1,8-naphthyridine derivatives and pharmaceutical compositions containing such derivatives. Methods of the invention comprise administration of a naphthyridine derivative of the invention for the treatment of diabetes and related disorders.
摘要:
This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly cancer.
摘要:
The invention relates to novel compounds and processes for their preparation and their use for preparing medicaments for the treatment of disorders, especially hyper-proliferative disorders.
摘要:
The present invention relates to novel compounds which are useful in the treatment of diabetes and diabetes-related disorders. The invention also relates to pharmaceutical compositions comprising said compounds, intermediates useful in the preparation of said compounds, and methods of preparation.
摘要:
Application extension management may be provided. Upon logging into a user device by a user, a list of a plurality of extensions associated with the user may be retrieved from a central repository. Access to each of the plurality of extensions associated with the user on the user device may then be provided to the user device.
摘要:
Architecture that facilitates cross-boundary message tracking based on a trust relationship in existence between a sender network and a recipient network. A tracking service is deployed in each network as a proxy to obtain message events for each hop that passes the message on to the recipient. Tracking can include a search task and a get task. Messages can be found in reports that match message search criteria. The search task returns an array of search results objects, each object identifying a single tracking report. A selected object is pipelined into the get task to return the detailed tracking report for the selected message.
摘要:
Application extension management may be provided. Upon logging into a user device by a user, a list of a plurality of extensions associated with the user may be retrieved from a central repository. Access to each of the plurality of extensions associated with the user on the user device may then be provided to the user device.
摘要:
This invention relates to novel compounds (I) and processes for their preparation, methods of treating diseases, particularly cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly cancer.
摘要:
A notification mechanism that aggregates multiple email tracking status updates into a new type of aggregated message, and transports this new type of message according to a configured interval. The tracking status transported in this aggregated status message can be a positive delivery event, a negative delivery event, hand-off of ownership, or any information to be communicated. This information can be delivered to email users to provide information about the message delivery and, routed to messaging system applications such as journaling (to allow rich delivery information in a journal report) and/or high-availability transport (to allow resubmission of a message in case of hardware failure).