Vaginal treatment composition
    2.
    发明申请
    Vaginal treatment composition 有权
    阴道治疗组合物

    公开(公告)号:US20070026074A1

    公开(公告)日:2007-02-01

    申请号:US11194064

    申请日:2005-07-29

    IPC分类号: A61K9/14 A61K31/70 A61K31/045

    摘要: A vaginal treatment composition that rapidly forms a gel when placed into contact with monovalent or polyvalent cations, such as sodium (Na+) and calcium (Ca2+) cations naturally found in vaginal mucosa, is provided. The gel may form in less than about 1 hour, in some embodiments less than about 1 minute, and in some embodiments, less than about 30 seconds. Among other things, such rapid gelation reduces the likelihood of leakage during use. In addition, because the gel may form intravaginally, it is more likely to retain its structure and shape over an extended period of time. In this manner, the gel may provide the prolonged release of a therapeutic agent that inhibits and/or treats vaginal infection. For instance, the gel may remain within the vagina for about 2 to about 48 hours to provide the desired effect.

    摘要翻译: 当与一价或多价阳离子接触时迅速形成凝胶的阴道处理组合物,例如天然存在的钠(Na +)+和钙(Ca 2+)+阳离子 提供阴道粘膜。 凝胶可以在小于约1小时,在一些实施方案中小于约1分钟,并且在一些实施方案中小于约30秒形成。 除此之外,这种快速凝胶化可降低使用过程中泄漏的可能性。 另外,因为凝胶可以阴道内形成,所以更可能在延长的时间段内保持其结构和形状。 以这种方式,凝胶可提供抑制和/或治疗阴道感染的治疗剂的延长释放。 例如,凝胶可以保留在阴道内约2至约48小时以提供期望的效果。

    Binary thermo-gelling composition
    3.
    发明申请
    Binary thermo-gelling composition 有权
    二元热凝胶组合物

    公开(公告)号:US20050287087A1

    公开(公告)日:2005-12-29

    申请号:US10877855

    申请日:2004-06-25

    摘要: There is provided a new thermo-gelling composition made with methylcellulose and citric acid. This composition may also have an effective amount of a treating agent, which may be a medicinal agent, cosmetic agent, moisturizer, adjuvant, nutritional agent, other ingredients and combinations thereof. The composition is useful in delivering moisturizers or pharmaceutically active agents to the user in a controlled release manner through the mucosal tissues in a body cavity, or on body surfaces, or as a subcutaneously injected medicament. The composition may also be used as a replacement for the soft tissues of the body as in, for example, the foot cushion and cartilage repair.

    摘要翻译: 提供了由甲基纤维素和柠檬酸制成的新的热凝胶组合物。 该组合物还可以具有有效量的处理剂,其可以是药剂,化妆品,保湿剂,佐剂,营养剂,其它成分及其组合。 该组合物可用于通过体腔或身体表面的粘膜组织或皮下注射的药物以控制释放的方式向使用者输送保湿剂或药物活性剂。 该组合物还可以用作身体的软组织的替代物,例如在脚垫和软骨修复中。

    Therapeutic article including a personal care composition and methods of making the therapeutic article
    4.
    发明申请
    Therapeutic article including a personal care composition and methods of making the therapeutic article 有权
    包括个人护理组合物和制备治疗用品的方法的治疗用品

    公开(公告)号:US20070135777A1

    公开(公告)日:2007-06-14

    申请号:US11300601

    申请日:2005-12-14

    IPC分类号: A61F13/00

    摘要: A therapeutic article includes a skin contact layer having a plurality of fibers forming a plurality of point-bearing surfaces configured for wear against a user's skin; a personal care composition disposed proximate the fibers; an external layer attached to the skin contact layer; and an intermediate layer interposed between the skin contact layer and the external layer, the intermediate layer being configured to activate the personal care composition, the external layer being configured to direct the activated personal care composition through the skin contact layer to treat the user.

    摘要翻译: 治疗用品包括皮肤接触层,所述皮肤接触层具有多个纤维,所述多个纤维形成用于对使用者的皮肤的磨损的多个点支承表面; 设置在纤维附近的个人护理组合物; 附着于皮肤接触层的外层; 以及介于皮肤接触层和外层之间的中间层,所述中间层被配置为激活个人护理组合物,所述外层被配置为引导所述活化的个人护理组合物通过所述皮肤接触层以治疗所述使用者。

    Therapeutic agents for inhibiting and/or treating vaginal infection
    5.
    发明申请
    Therapeutic agents for inhibiting and/or treating vaginal infection 失效
    用于抑制和/或治疗阴道感染的治疗剂

    公开(公告)号:US20060105963A1

    公开(公告)日:2006-05-18

    申请号:US11194039

    申请日:2005-07-29

    IPC分类号: A61K31/70 A61K31/045

    摘要: A vaginal treatment composition that employs a therapeutic agent to inhibit and/or treat vaginal infection is provided. The therapeutic agent is capable of inhibiting and/or killing Gardnerella (e.g., Gardnerella vaginalis), Candida (e.g., Candida albicans), and/or Trichomonas (e.g., Trichomonas vaginalis) pathogens. Desirably, such antimicrobial efficacy is achieved without substantially inhibiting the growth of Lactobacillus acidophilus. For instance, sugars and/or sugar alcohols may be employed in the present invention as a therapeutic agent for inhibiting and/or treating vaginal infection. In one particular embodiment, D-xylitol is used as the therapeutic agent.

    摘要翻译: 提供了使用治疗剂抑制和/或治疗阴道感染的阴道治疗组合物。 治疗剂能够抑制和/或杀死加德纳(Gardnerella vaginalis),假丝酵母​​(例如白色假丝酵母)和/或毛滴虫(例如阴道毛滴虫)病原体。 理想地,实现了这样的抗微生物效能,而基本上不抑制嗜酸乳杆菌的生长。 例如,本发明中可以使用糖和/或糖醇作为抑制和/或治疗阴道感染的治疗剂。 在一个具体实施方案中,D-木糖醇用作治疗剂。

    Xylitol for treatment of vaginal infections
    6.
    发明授权
    Xylitol for treatment of vaginal infections 失效
    木糖醇用于治疗阴道感染

    公开(公告)号:US07619008B2

    公开(公告)日:2009-11-17

    申请号:US11194039

    申请日:2005-07-29

    IPC分类号: A61K31/045

    摘要: A vaginal treatment composition that employs a therapeutic agent to inhibit and/or treat vaginal infection is provided. The therapeutic agent is capable of inhibiting and/or killing Gardnerella (e.g., Gardnerella vaginalis), Candida (e.g., Candida albicans), and/or Trichomonas (e.g., Trichomonas vaginalis) pathogens. Desirably, such antimicrobial efficacy is achieved without substantially inhibiting the growth of Lactobacillus acidophilus. For instance, sugars and/or sugar alcohols may be employed in the present invention as a therapeutic agent for inhibiting and/or treating vaginal infection. In one particular embodiment, D-xylitol is used as the therapeutic agent.

    摘要翻译: 提供了使用治疗剂抑制和/或治疗阴道感染的阴道治疗组合物。 治疗剂能够抑制和/或杀死加德纳(Gardnerella vaginalis),念珠菌(例如白色念珠菌)和/或滴虫(例如阴道毛滴虫)病原体。 理想地,实现了这样的抗微生物效能,而基本上不抑制嗜酸乳杆菌的生长。 例如,本发明中可以使用糖和/或糖醇作为抑制和/或治疗阴道感染的治疗剂。 在一个具体实施方案中,D-木糖醇用作治疗剂。