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公开(公告)号：US07604351B2
公开(公告)日：2009-10-20
申请号：US12055954
申请日：2008-03-26
IPC分类号： A61B3/14
CPC分类号： G01B9/0203 , A61B3/102 , G01B9/02044 , G01B9/02067 , G01B9/02091 , G01B2290/65 , G01N21/4795
摘要： An optical image measurement device comprises: an interference-light generator configured to generate an interference light by splitting a low-coherence light into a signal light and a reference light and superimposing the signal light having passed through an eye and the reference light having passed through a reference object; a detector configured to detect the generated interference light; a calculator configured to obtain intensity distribution of the interference light in the eye, based on a result of the detection by the detector; a determining part configured to determine a projection position of the signal light to the eye, based on the obtained intensity distribution; and an image forming part configured to form an image of the eye, based on a result of detection of a new interference light based on a new signal light projected toward the determined projection position and a new reference light having passed through the reference object.
摘要翻译： 光学图像测量装置包括：干涉光发生器，被配置为通过将低相干光分解成信号光和参考光来产生干涉光，并叠加已经通过眼睛的信号光和已经穿过的参考光 参考对象; 检测器，被配置为检测所产生的干涉光; 配置为基于检测器的检测结果获得眼睛中的干涉光的强度分布的计算器; 确定部件，被配置为基于获得的强度分布来确定信号光对眼睛的投影位置; 以及基于对所确定的投影位置投射的新的信号光的新的干涉光的检测结果和通过所述参照对象的新的基准光，构成为形成所述眼睛的图像的图像形成部。
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公开(公告)号：US07492466B2
公开(公告)日：2009-02-17
申请号：US11246394
申请日：2005-10-11
申请人： Kinpui Chan , Masahiro Akiba , Yasufumi Fukuma , Hiroyuki Otsuka , Hisashi Tsukada , Kazuhiko Yumikake
发明人： Kinpui Chan , Masahiro Akiba , Yasufumi Fukuma , Hiroyuki Otsuka , Hisashi Tsukada , Kazuhiko Yumikake
IPC分类号： G01B11/02
CPC分类号： G01B9/02007 , G01B9/02003 , G01B9/02014 , G01B9/02027 , G01B9/02044 , G01B9/02069 , G01B9/02091 , G01B11/2441 , G01B2290/45 , G01B2290/65 , G01B2290/70
摘要： Provided is an optical image measuring apparatus forming a three-dimensional image based on tomographic images of an object, acquired at various depths even when the object moves during measurement. Including a half mirror (6) for dividing a light beam signal light (S) and reference light (R), a frequency shifter (8), a reference mirror (9) and a piezoelectric element (9A) used to change an optical path length of the reference light (R), CCDs (21, 22) for receiving interference light beams (L) resulting from interference light produced by superimposing the signal light (S) and the reference light (R) on each other by the half mirror (6) and outputting detection signals, an image forming portion for forming tomographic images based on the detection signals, a measurement depth calculating means (53), and an image processing portion (57). Forming a three-dimensional image or the like based on the arranged tomographic images.
摘要翻译： 提供一种光学图像测量装置，其即使在测量期间物体移动时，也可以基于在各种深度获取的物体的断层图像形成三维图像。 包括用于分割光束信号光（S）和参考光（R）的半反射镜（6），用于改变光路的变频器（8），参考反射镜（9）和压电元件（9A） 参考光（R）的长度，用于接收由半反射镜将信号光（S）和参考光（R）彼此叠加而产生的干涉光所产生的干涉光束（L）的CCD（21,22） （6）并输出检测信号，基于检测信号形成断层图像的图像形成部分，测量深度计算装置（53）和图像处理部分（57）。 基于排列的断层图像形成三维图像等。
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公开(公告)号：US07372578B2
公开(公告)日：2008-05-13
申请号：US11223928
申请日：2005-09-13
申请人： Masahiro Akiba , Kinpui Chan , Yasufumi Fukuma , Hiroyuki Otsuka , Hisashi Tsukada , Kazuhiko Yumikake
发明人： Masahiro Akiba , Kinpui Chan , Yasufumi Fukuma , Hiroyuki Otsuka , Hisashi Tsukada , Kazuhiko Yumikake
IPC分类号： G02B9/02
CPC分类号： G01B9/02014 , G01B9/02003 , G01B9/02027 , G01B9/02069 , G01B9/02091 , G01B11/2441 , G01B2290/45 , G01B2290/70
摘要： Provided is an optical image measuring apparatus capable of effectively receiving interference light, particularly an alternating current component thereof using a smaller number of photo sensors. The optical image measuring apparatus includes a polarizing plate for converting a light beam from a broad-band light source to linearly polarized light, a half mirror for dividing the light beam into signal light and reference light, a piezoelectric element for vibrating a reference mirror, a wavelength plate for converting the reference light to circularly polarized light, a polarization beam splitter for extracting two different polarized light components from interference light produced from the signal light and the reference light which are superimposed on each other by the half mirror, CCDs for detecting the two different polarized light components, and a signal processing portion for producing an image of an object to be measured based on the detected polarized light components. A frequency for intensity modulation of the light beam is synchronized with a beat frequency of the interference light. A frequency of vibration of the reference mirror is synchronized with the beat frequency of the interference light and an amplitude of vibration thereof is set to be equal to or smaller than a wavelength of the interference light.
摘要翻译： 提供一种光学图像测量装置，其能够使用较少数量的光传感器有效地接收干涉光，特别是其交流分量。 该光学图像测量装置包括用于将来自宽带光源的光束转换为线偏振光的偏振片，用于将光束分成信号光的半反射镜和参考光，用于振动参考反射镜的压电元件， 用于将参考光转换成圆偏振光的波长板，用于从由半反射镜彼此叠加的信号光和参考光产生的干涉光中提取两种不同的偏振光分量的偏振分束器，用于检测的CCD 两个不同的偏振光分量，以及用于基于检测到的偏振光分量产生待测物体的图像的信号处理部分。 光束的强度调制频率与干涉光的拍频同步。 参考反射镜的振动频率与干涉光的拍频同步，其振动振幅被设定为等于或小于干涉光的波长。
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公开(公告)号：US20060055939A1
公开(公告)日：2006-03-16
申请号：US11223928
申请日：2005-09-13
申请人： Masahiro Akiba , Kinpui Chan , Yasufumi Fukuma , Hiroyuki Otsuka , Hisashi Tsukada , Kazuhiko Yumikake
发明人： Masahiro Akiba , Kinpui Chan , Yasufumi Fukuma , Hiroyuki Otsuka , Hisashi Tsukada , Kazuhiko Yumikake
IPC分类号： G01B11/02
CPC分类号： G01B9/02014 , G01B9/02003 , G01B9/02027 , G01B9/02069 , G01B9/02091 , G01B11/2441 , G01B2290/45 , G01B2290/70
摘要： Provided is an optical image measuring apparatus capable of effectively receiving interference light, particularly an alternating current component thereof using a smaller number of photo sensors. The optical image measuring apparatus includes a polarizing plate for converting a light beam from a broad-band light source to linearly polarized light, a half mirror for dividing the light beam into signal light and reference light, a piezoelectric element for vibrating a reference mirror, a wavelength plate for converting the reference light to circularly polarized light, a polarization beam splitter for extracting two different polarized light components from interference light produced from the signal light and the reference light which are superimposed on each other by the half mirror, CCDs for detecting the two different polarized light components, and a signal processing portion for producing an image of an object to be measured based on the detected polarized light components. A frequency for intensity modulation of the light beam is synchronized with a beat frequency of the interference light. A frequency of vibration of the reference mirror is synchronized with the beat frequency of the interference light and an amplitude of vibration thereof is set to be equal to or smaller than a wavelength of the interference light.
摘要翻译： 提供一种光学图像测量装置，其能够使用较少数量的光传感器有效地接收干涉光，特别是其交流分量。 该光学图像测量装置包括用于将来自宽带光源的光束转换为线偏振光的偏振片，用于将光束分成信号光的半反射镜和参考光，用于振动参考反射镜的压电元件， 用于将参考光转换成圆偏振光的波长板，用于从由半反射镜彼此叠加的信号光和参考光产生的干涉光中提取两种不同的偏振光分量的偏振分束器，用于检测的CCD 两个不同的偏振光分量，以及用于基于检测到的偏振光分量产生待测物体的图像的信号处理部分。 光束的强度调制频率与干涉光的拍频同步。 参考反射镜的振动频率与干涉光的拍频同步，其振动振幅被设定为等于或小于干涉光的波长。
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公开(公告)号：US20060077395A1
公开(公告)日：2006-04-13
申请号：US11246394
申请日：2005-10-11
申请人： Kinpui Chan , Masahiro Akiba , Yasufumi Fukuma , Hiroyuki Otsuka , Hisashi Tsukada , Kazuhiko Yumikake
发明人： Kinpui Chan , Masahiro Akiba , Yasufumi Fukuma , Hiroyuki Otsuka , Hisashi Tsukada , Kazuhiko Yumikake
IPC分类号： G01B11/02
CPC分类号： G01B9/02007 , G01B9/02003 , G01B9/02014 , G01B9/02027 , G01B9/02044 , G01B9/02069 , G01B9/02091 , G01B11/2441 , G01B2290/45 , G01B2290/65 , G01B2290/70
摘要： Provided is an optical image measuring apparatus forming a three-dimensional image based on tomographic images of an object, acquired at various depths even when the object moves during measurement. Including a half mirror (6) for dividing a light beam signal light (S) and reference light (R), a frequency shifter (8), a reference mirror (9) and a piezoelectric element (9A) used to change an optical path length of the reference light (R), CCDs (21, 22) for receiving interference light beams (L) resulting from interference light produced by superimposing the signal light (S) and the reference light (R) on each other by the half mirror (6) and outputting detection signals, an image forming portion for forming tomographic images based on the detection signals, a measurement depth calculating means (53), and an image processing portion (57). Forming a three-dimensional image or the like based on the arranged tomographic images.
摘要翻译： 提供一种光学图像测量装置，其即使在测量期间物体移动时，也可以基于在各种深度获取的物体的断层图像形成三维图像。 包括用于分割光束信号光（S）和参考光（R）的半反射镜（6），用于改变光学器件的变频器（8），参考反射镜（9）和压电元件（9A） 参考光（R）的路径长度，用于接收由将信号光（S）和参考光（R）叠加在一起而产生的干涉光所产生的干涉光（L）的CCD（21,22） 反射镜（6）并输出检测信号，基于检测信号形成断层图像的图像形成部分，测量深度计算装置（53）和图像处理部分（57）。 基于排列的断层图像形成三维图像等。
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公开(公告)号：US20080151260A1
公开(公告)日：2008-06-26
申请号：US11962196
申请日：2007-12-21
IPC分类号： G01B9/02
CPC分类号： G01B9/02067 , A61B3/102 , G01B9/0203 , G01B9/02044 , G01B9/02064 , G01B9/02089 , G01B9/02091 , G01N21/4795
摘要： A fundus oculi observation device acts as an optical image measurement device capable of measuring an OCT image such as a tomographic image of a fundus oculi, or the like, and is configured so as to calculate the signal level of the formed OCT image, determine whether the signal level exceeds a threshold value, and change the position of a reference mirror so that the signal level is determined to exceed the threshold value.
摘要翻译： 眼底观察装置作为能够测量诸如眼底断层图像等OCT图像的光学图像测量装置，并且被配置为计算形成的OCT图像的信号电平，确定是否 信号电平超过阈值，并且改变参考镜的位置，使得信号电平被确定为超过阈值。
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公开(公告)号：US20070188704A1
公开(公告)日：2007-08-16
申请号：US11675657
申请日：2007-02-16
申请人： Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa
发明人： Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa
IPC分类号： A61B3/10
CPC分类号： A61B3/102
摘要： Technology is provided, capable of easily acquiring high precision tomographic images of the desired observation site of the fundus oculi. A fundus observation device 1 is provided, comprising: an interferometer that generates interference light LC from a reference light LR via a reference mirror 174 and a signal light LS that reaches the fundus oculi Ef after low-coherence light L0 is split into that signal light LS and reference light LR; a CCD 184 that detects interference light LC; an image forming part 220 that forms image data G of a tomographic image based on detection results of the CCD 184; a display part 240A; an operation part 240B for specifying an observation mode (observation site); and a reference mirror drive mechanism 243. The image data G of a tomographic image includes image data of a normal image G (Re) and an inverse image G (Im). A controlling part 210 that displays the selected normal image G (Re) or inverse image G (Im) on the display part 240A along with moving the reference mirror 174 by controlling the reference mirror drive mechanism 243 based on the selected observation mode.
摘要翻译： 提供技术，能够容易地获取眼底的所需观察部位的高精度断层图像。 提供了一种眼底观察装置1，其包括：干涉仪，其经由参考镜174产生来自参考光LR的干涉光LC和在低相干光L 0被分割成该信号之后到达眼底Ef的信号光LS 光LS和参考光LR; 检测干涉光LC的CCD184; 基于CCD 184的检测结果形成断层图像的图像数据G的图像形成部220; 显示部分240A; 用于指定观察模式（观察部位）的操作部240B; 和参考镜驱动机构243。 断层图像的图像数据G包括正常图像G（Re）和逆图像G（Im）的图像数据。 控制部210，通过基于所选择的观察模式控制参考镜驱动机构243，在显示部240A上显示所选择的正常图像G（Re）或反转图像G（Im）。
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公开(公告)号：US08348426B2
公开(公告)日：2013-01-08
申请号：US12052187
申请日：2008-03-20
IPC分类号： A61B3/14
CPC分类号： A61B3/102 , G01B9/0203 , G01B9/02044 , G01B9/02085 , G01B9/02087 , G01B9/02091 , G01B2290/65 , G06T3/4007
摘要： An optical image measurement device is configured to form a tomographic image at each of a plurality of cross sections of a measurement object, and the optical image measurement device comprises: an image processor configured to execute an arithmetic operation based on a tomographic image at one cross section of the plurality of cross sections and another tomographic image at each of one or more cross sections other than the one cross section, thereby forming a new tomographic image at the one cross section.
摘要翻译： 光学图像测量装置被配置为在测量对象的多个横截面中的每一个处形成断层图像，并且所述光学图像测量装置包括：图像处理器，被配置为在一个十字交叉处执行基于断层图像的算术运算 所述多个横截面的截面和在所述一个横截面以外的一个或多个横截面中的每一个处的另一断层图像，从而在所述一个横截面处形成新的断层图像。
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9.发明授权公开(公告)号：US07905596B2
公开(公告)日：2011-03-15
申请号：US11760314
申请日：2007-06-08
CPC分类号： A61B3/102 , G06T7/12 , G06T7/174 , G06T7/181 , G06T2207/10101 , G06T2207/30041
摘要： First image forming part forms a two-dimensional surface image of a fundus oculi of an eye based on optically obtained data. Second image forming part forms tomographic images of fundus oculi based on data obtained by optically scanning a region of the surface of fundus oculi corresponding to at least part of two-dimensional image. Accumulated image generating part generates an accumulated image by accumulating the formed tomographic images in a depth-wise direction. Extracting part extracts first vascular territory corresponding to a fundus oculi vessel from two-dimensional image formed by first image forming part, and also extracts second vascular territory corresponding to a fundus oculi vessel from accumulated image generated by accumulated image generating part. Specification part specifies a position of a vascular cross sectional region corresponding to a cross section of a fundus oculi vessel in the tomographic image based on extracted first vascular territory and extracted second vascular territory.
摘要翻译： 第一图像形成部件基于光学获得的数据形成眼睛的眼底的二维表面图像。 第二图像形成部分基于通过光学扫描与至少部分二维图像相对应的眼底表面的区域获得的数据来形成眼底的断层图像。 累积图像生成部通过在深度方向累积形成的断层图像来生成累积图像。 提取部分从由第一图像形成部分形成的二维图像中提取与眼底容器相对应的第一血管区域，并且从由累积图像生成部分生成的累积图像中提取与眼底容器对应的第二血管区域。 规格部分基于提取的第一血管区域和提取的第二血管区域来指定与断层图像中的眼底血管的横截面对应的血管横截面区域的位置。
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10.发明授权Optical image measuring device, optical image measuring program, fundus observation device, and fundus observation program 有权光学图像测量装置，光学图像测量程序，眼底观察装置和眼底观察程序公开(公告)号：US07756311B2
公开(公告)日：2010-07-13
申请号：US11545270
申请日：2006-10-10
申请人： Yoshiaki Yasuno , Toyohiko Yatagai , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa , Hiroyuki Aoki , Takashi Fujimura
发明人： Yoshiaki Yasuno , Toyohiko Yatagai , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa , Hiroyuki Aoki , Takashi Fujimura
CPC分类号： G01N21/4795 , A61B3/102 , A61B3/145 , G01N2021/1787
摘要： An optical image measuring device which can form a highly reliable image even if an object moves during scanning of a signal light is provided. An optical image forming device 1 comprises: an interferometer that splits a low coherence light L0 into a signal light LS and a reference light LR and generates an interference light LC by overlaying the signal light LS reflected by a fundus oculi with the reference light LR reflected by a reference mirror 14; a CCD 34 which receives the interference light LC and outputs a detection signal; Galvanometer mirrors 22 and 23 to scan the signal light LS in a main scanning direction and a sub-scanning direction; and a computer 40 forming tomographic images G1 to Gm along the main scanning direction at different positions of the sub-scanning direction. The Galvanometer mirrors 22 and 23 scan the signal light LS in a given direction crossing the main scanning direction, and the computer 40 forms a tomographic image for correction GR along the given direction to correct displacement of each topographic image Gi based on the tomographic image for correction GR.
摘要翻译： 提供了即使在信号光的扫描期间物体移动时也可以形成高可靠性图像的光学图像测量装置。 光学图像形成装置1包括：干涉仪，其将低相干光L0分解成信号光LS和参考光LR，并通过将由眼底反射的信号光LS与反射的参考光LR重叠而产生干涉光LC 通过参考反射镜14; CCD34，其接收干涉光LC并输出检测信号; 电流计镜22和23在主扫描方向和副扫描方向扫描信号光LS; 以及在副扫描方向的不同位置沿着主扫描方向形成断层图像G1〜Gm的计算机40。 电流计反射镜22和23沿与主扫描方向相交的给定方向扫描信号光LS，并且计算机40沿着给定方向形成用于校正GR的断层图像，以校正基于断层图像的每个地形图像Gi的位移 校正GR。
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