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公开(公告)号:US20070054407A1
公开(公告)日:2007-03-08
申请号:US11487823
申请日:2006-07-17
申请人: Yu-Ju Chen , Po-Chiao Lin , Chun-Cheng Lin , Shu-Hua Chen , Po-Hung Chou , Hsin Liao
发明人: Yu-Ju Chen , Po-Chiao Lin , Chun-Cheng Lin , Shu-Hua Chen , Po-Hung Chou , Hsin Liao
IPC分类号: G01N33/551
CPC分类号: B82Y15/00 , B82Y30/00 , G01N33/54333 , G01N33/6851
摘要: The present invention provides methods, compositions, and systems for mass spectrometric analysis of magnetic nanoparticles displaying ligands on their surface. For example, the present invention provides methods of screening a sample for the presence of at least one analyte using ligand conjugated magnetic nanoparticles, magnetic separation, and mass spectrometric analysis. The present invention also relates to MALDI matrix compositions comprising ligand conjugated magnetic nanoparticles.
摘要翻译: 本发明提供了在其表面上显示配体的磁性纳米颗粒的质谱分析的方法,组合物和系统。 例如,本发明提供了使用配体共轭磁性纳米颗粒筛选样品以存在至少一种分析物的方法,磁分离和质谱分析。 本发明还涉及包含配体缀合的磁性纳米颗粒的MALDI基质组合物。