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公开(公告)号:US08877786B2
公开(公告)日:2014-11-04
申请号:US14093956
申请日:2013-12-02
申请人: Yuki Iwaki , Toshio Kawanami , Gary Michael Ksander , Muneto Moji
发明人: Yuki Iwaki , Toshio Kawanami , Gary Michael Ksander , Muneto Moji
IPC分类号: A61K31/41 , A61K31/42 , C07D257/06 , C07D261/14 , C07D231/40 , A61K45/00
CPC分类号: A61K31/41 , A61K31/42 , A61K45/00 , C07D231/40 , C07D257/06 , C07D261/14
摘要: The present invention provides a compound of formula I; or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R6, A1, A2, X1, s and m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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公开(公告)号:US20140088165A1
公开(公告)日:2014-03-27
申请号:US14093956
申请日:2013-12-02
申请人: Yuki Iwaki , Toshio KAWANAMI , Gary Michael Ksander , Muneto Moji
发明人: Yuki Iwaki , Toshio KAWANAMI , Gary Michael Ksander , Muneto Moji
IPC分类号: C07D261/14 , C07D231/40 , C07D257/06
CPC分类号: A61K31/41 , A61K31/42 , A61K45/00 , C07D231/40 , C07D257/06 , C07D261/14
摘要: The present invention provides a compound of formula I; or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R6, A1, A2, X1, s and m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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