公开(公告)号：US06992178B2

公开(公告)日：2006-01-31

申请号：US10416178

申请日：2001-10-17

申请人： Yukio Kato ,  Shinichi Tsutsumi ,  Ryo Oda ,  Hideaki Shintani ,  Masahiro Nishimura

发明人： Yukio Kato ,  Shinichi Tsutsumi ,  Ryo Oda ,  Hideaki Shintani ,  Masahiro Nishimura

IPC分类号： C07K14/00 ,  A61K38/16

CPC分类号： C12N5/0654 ,  A61K35/12 ,  C07K14/42 ,  C12N5/0655 ,  C12N5/0663 ,  C12N5/0664 ,  C12N2501/59

摘要： The invention provides an agent for conferring resistance comprising a lectin as an effective component, which are able to confer resistance against external stimuli to animal cells, particularly mammalian cells, and to their cultured cells and various tissues in the living bodies. The agent for conferring resistance to external stimulus according to the invention can confer to such animal cells and/or tissues resistance against mechanical stimuli and/or proteolytic reactions, and thereby enhance graft fixation of the cells and/or tissues, as well as transplant tissues obtained by culturing them.

摘要翻译： 本发明提供了赋予抗性的试剂，其包含作为有效成分的凝集素，其能够赋予动物细胞，特别是哺乳动物细胞及其培养的细胞和生物体中的各种组织对外部刺激的抵抗力。 根据本发明赋予对外部刺激的抗性的试剂可以赋予这种动物细胞和/或组织对机械刺激和/或蛋白水解反应的抗性，从而增强细胞和/或组织以及移植组织的移植物固定 通过培养获得。

公开(公告)号：US06310026B1

公开(公告)日：2001-10-30

申请号：US09813802

申请日：2001-03-22

申请人： Hideaki Shintani ,  Masayuki Okazaki ,  Yasuhiro Yoshida ,  Kenichi Shirai ,  Bart Van Meerbeek ,  Daisuke Usuki

发明人： Hideaki Shintani ,  Masayuki Okazaki ,  Yasuhiro Yoshida ,  Kenichi Shirai ,  Bart Van Meerbeek ,  Daisuke Usuki

IPC分类号： C11D300

CPC分类号： C11D7/08 ,  C11D3/3947 ,  C11D7/5004

摘要： A method of cleaning of an inorganic filler, upon which the inorganic filler used in resin materials for industrial or biological use, particularly dental resin restorative materials, can be more firmly bound to a resin matrix as a substrate, as well as a method of surface processing of the inorganic filler, are provided. The inorganic filler surface is cleaned with an aqueous solution of a peroxo acid and/or a peroxo acid salt, washed with water, and then cleaned with an organic solvent. Further, the cleaned inorganic filler is subjected to a silane coupling processing, thereby the inorganic filler being processed.

摘要翻译： 用于工业或生物用途的树脂材料中使用的无机填料，特别是牙科树脂修复材料的无机填料的清洁方法可以更牢固地结合到作为基材的树脂基质，以及表面的方法 提供无机填料的加工。 无机填料表面用过氧酸和/或过氧酸盐水溶液清洗，用水洗涤，然后用有机溶剂清洗。 另外，将清洗后的无机填料进行硅烷偶联处理，由此处理无机填料。