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公开(公告)号:US08481688B2
公开(公告)日:2013-07-09
申请号:US13105521
申请日:2011-05-11
申请人: Zhigang Weng , William M. Winston, Jr. , Ailin Bai , Kristan Meetze , Solly Weiler , Ting Chen , Jeno Gyuris
发明人: Zhigang Weng , William M. Winston, Jr. , Ailin Bai , Kristan Meetze , Solly Weiler , Ting Chen , Jeno Gyuris
IPC分类号: C07K16/28
CPC分类号: C07K16/2863 , A61K2039/505 , C07K2317/24 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要: Monoclonal antibodies that bind and inhibit biological activities of human FGFR2 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation or overexpression of FGFR2.
摘要翻译: 公开了结合和抑制人FGFR2的生物学活性的单克隆抗体。 抗体可用于治疗与FGFR2的活化或过表达相关的细胞增殖性疾病和病症,包括某些形式的癌症。
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公开(公告)号:US20110305687A1
公开(公告)日:2011-12-15
申请号:US13105521
申请日:2011-05-11
申请人: Zhigang Weng , William M. Winston, JR. , Ailin Bai , Kristan Meetze , Solly Weiler , Ting Chen , Jeno Gyuris
发明人: Zhigang Weng , William M. Winston, JR. , Ailin Bai , Kristan Meetze , Solly Weiler , Ting Chen , Jeno Gyuris
IPC分类号: A61K39/395 , C12N15/63 , C12P21/02 , A61P35/00 , C07K16/40 , C12N5/10 , C12N1/21 , C07H21/00 , C12N5/09
CPC分类号: C07K16/2863 , A61K2039/505 , C07K2317/24 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要: Monoclonal antibodies that bind and inhibit biological activities of human FGFR2 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation or overexpression of FGFR2.
摘要翻译: 公开了结合和抑制人FGFR2的生物学活性的单克隆抗体。 抗体可用于治疗与FGFR2的活化或过表达相关的细胞增殖性疾病和病症,包括某些形式的癌症。
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