N3-Pyridyl-Thiamine And Its Use In Cancer Treatments
    9.
    发明申请
    N3-Pyridyl-Thiamine And Its Use In Cancer Treatments 审中-公开
    N3-吡啶基硫胺素及其在癌症治疗中的应用

    公开(公告)号:US20080234304A1

    公开(公告)日:2008-09-25

    申请号:US10594191

    申请日:2005-03-23

    IPC分类号: A61K31/51 C12N5/00 A61P43/00

    CPC分类号: A61K31/4439

    摘要: The invention provides methods using N3-pyridyl-thiamine compounds and pharmaceutical compositions comprising N3-pyridyl-thiamine, which are especially useful for preventing or reducing tumor growth in vivo. The invention is also directed to the benefits of reducing thiamine concentrations, e.g., by means of a thiamine reduced diet, as an effective step in a therapeutic regime for patients treated with N3-pyridyl-thiamine.

    摘要翻译: 本发明提供了使用N 3 - 吡啶基 - 硫胺素化合物的方法和包含N 3 - 吡啶基 - 硫胺素的药物组合物,其特别可用于预防或减少体内肿瘤生长。 本发明还涉及降低硫胺素浓度的益处,例如通过硫胺素减少饮食,作为用N 3 - 吡啶基硫胺素治疗的患者的治疗方案的有效步骤。