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    LACTIC ACID BACTERIA, METHODS AND USES THEREOF
    1.
    发明申请
    LACTIC ACID BACTERIA, METHODS AND USES THEREOF 有权

    公开(公告)号：US20220168365A1

    公开(公告)日：2022-06-02

    申请号：US17670968

    申请日：2022-02-14

    申请人： BIOGAIA AB

    发明人： Stefan Roos

    IPC分类号： A61K35/747 ,  C12N1/20

    摘要： The present invention relates to novel strains of lactic acid bacteria, more specifically, novel strains of Lactobacillus reuteri, capable of utilizing ethanolamine. This characteristic makes it possible for the bacteria to compete for the same substrate as pathogenic ethanolamine-utilizing pathogens, thereby presenting an effective means to combat infections resulting from such pathogenic bacteria. There is also provided a method of selecting further ethanolamine-utilizing lactic acid bacteria, as well as other methods and uses involving said novel strains and other ethanolamine-utilizing lactic acid bacteria.

    Use of selected lactic acid bacteria for reducing infantile colic
    4.
    发明申请
    Use of selected lactic acid bacteria for reducing infantile colic 有权
    使用选择的乳酸菌减少婴儿腹痛

    公开(公告)号：US20120121564A1

    公开(公告)日：2012-05-17

    申请号：US13355585

    申请日：2012-01-23

    申请人： Eamonn Connolly ,  Bo Mollstam

    发明人： Eamonn Connolly ,  Bo Mollstam

    IPC分类号： A61K35/74 ,  A61P1/06

    CPC分类号： C12R1/225 ,  A61K31/22 ,  A61K35/747 ,  C12N1/20 ,  Y10S435/853

    摘要： The invention herein provides certain strains of lactic acid bacteria selected for their capability of promoting production of IL-10 and consequently proliferation of CD4+CD25+ TR cells, for prophylaxis and/or treatment of infant colic, a method of selecting such strains, and products containing such strains.

    摘要翻译： 本发明提供了一些选择用于促进IL-10的产生和随后CD4 + CD25 + TR细胞增殖，用于预防和/或治疗婴儿绞痛，选择这种菌株的方法和产品的某些乳酸菌菌株 含有这些菌株。

    Antibiotic reuterin
    6.
    发明授权
    Antibiotic reuterin 失效
    抗生素罗伊氏菌素

    公开(公告)号：US5413960A

    公开(公告)日：1995-05-09

    申请号：US097871

    申请日：1993-07-27

    申请人： Walter J. Dobrogosz ,  Sven E. Lindgren

    发明人： Walter J. Dobrogosz ,  Sven E. Lindgren

    IPC分类号： C07D319/06 ,  C12P17/06 ,  C12N9/02 ,  C12N9/99

    CPC分类号： C12R1/225 ,  C07D319/06 ,  C12P17/06

    摘要： The antibiotic .beta.-hydroxypropionaldehyde is obtained by cultivating strains of Lactobacillus reuteri under anaerobic conditions in the presence of glycerol or glyceraldehyde. This antibiotic has activity against Gram positive and Gram negative bacteria, against the yeast, Saccharomyces cerevisiae, and against the protozoan, Trypanosoma cruzi, and decreases ribonucleotide reductase activity.

    摘要翻译： 通过在甘油或甘油醛的存在下，在厌氧条件下培养罗伊氏乳杆菌菌株获得抗生素β-羟基丙醛。 这种抗生素具有抗革兰氏阳性和革兰氏阴性菌对酵母，酿酒酵母和针对原生动物，克氏锥虫的活性，降低核糖核苷酸还原酶活性。

    SEROTONIN PRODUCING BACTERIA
    8.
    发明申请
    SEROTONIN PRODUCING BACTERIA 有权

    公开(公告)号：US20220354909A1

    公开(公告)日：2022-11-10

    申请号：US17623543

    申请日：2020-11-06

    申请人： BIOGAIA AB

    发明人： Estelle Grasset ,  Muhammed Khan ,  Bo Möllstam ,  Stefan Roos

    IPC分类号： A61K35/747 ,  C12N1/20 ,  C12Q1/02 ,  A61P25/00

    摘要： The invention relates to selection of bacterial strain for use in treating serotonin deficiency and/or a disease related to serotonin deficiency by culturing bacteria of a lactic acid producing bacterial strain, under aerobic conditions, in a culture medium comprising tryptophan. Any serotonin produced by the bacteria of the lactic acid producing bacterial strain in the culture medium is detected and the lactic acid producing bacterial strain is selected as effective in treating serotonin deficiency and/or a disease related to serotonin deficiency in a subject if serotonin is detected in the culture medium.

    Lactic acid bacteria, methods and uses thereof
    9.
    发明授权
    Lactic acid bacteria, methods and uses thereof 有权

    公开(公告)号：US11285181B2

    公开(公告)日：2022-03-29

    申请号：US16496509

    申请日：2018-03-27

    申请人： BIOGAIA AB

    发明人： Stefan Roos

    IPC分类号： A61K35/747 ,  C12N1/20 ,  A61K35/00 ,  C12R1/225

    摘要： The present invention relates to novel strains of lactic acid bacteria, more specifically, novel strains of Lactobacillus reuteri, capable of utilizing ethanolamine. This characteristic makes it possible for the bacteria to compete for the same substrate as pathogenic ethanolamine-utilizing pathogens, thereby presenting an effective means to combat infections resulting from such pathogenic bacteria. There is also provided a method of selecting further ethanolamine-utilizing lactic acid bacteria, as well as other methods and uses involving said novel strains and other ethanolamine-utilizing lactic acid bacteria.