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公开(公告)号：US20230140530A1
公开(公告)日：2023-05-04
申请号：US18087993
申请日：2022-12-23
发明人： Weston HARDING , Jon BURKHOLZ , Huibin LIU , Ken CLUFF , Lawrence TRAINER , Stephen BORNHOFT , Yiping MA , Weston WHITAKER , Ralph SONDEREGGER
摘要： A catheter assembly comprises a catheter (18), a needle (12) having a sharp distal tip disposed within the catheter (18), a catheter hub (14) connected to the catheter (18) having the needle (12) passing therethrough, the catheter hub (14) including a valve (38) that selectively permits or blocks a flow of fluid through the catheter (18), a valve actuator (54) that moves between a first position and a second position, and a return member (56) that returns the valve actuator (54) from the second position to the first position, and a needle protection member (176) that encloses the sharp distal tip of the needle (12).
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公开(公告)号：US20230135459A1
公开(公告)日：2023-05-04
申请号：US17972765
申请日：2022-10-25
IPC分类号： A61B5/15
摘要： A blood draw device for use with a peripheral intravenous catheter (PIVC) includes a catheter having a proximal end, a distal end, and a sidewall defining a lumen, a secondary catheter having a proximal end, a distal end, and a sidewall defining a lumen, an introducer having a proximal end, a distal end, and a sidewall defining an inner volume configured to movably receive the catheter, and an actuator movably coupled to the introducer. The actuator having a first portion disposed outside of the introducer and a second portion disposed in the inner volume of the introducer. The second portion of the actuator having a main body with a first height and an extension with a second height. The main body and the extension define an opening, with the catheter and the secondary catheter attached to the actuator and in fluid communication with the opening.
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公开(公告)号：US20230130563A1
公开(公告)日：2023-04-27
申请号：US18089152
申请日：2022-12-27
发明人： Andrew Richards , Michael Yarger , David E. Booth , Peter Quinn , Mircea Despa , Adam Martin
摘要： A delivery device for delivering a medical fluid to a patient has a housing configured for receiving a container at least partially filled with the medical fluid. The delivery device further has a drive mechanism associated with the housing configured for delivering the medical fluid from the container to the patient in a dosing procedure. The delivery device further has a module configured for detecting at least one of a property of the dosing procedure and a property of the medical fluid. The module has at least one dose detection sensor configured for detecting an initiation, progression, and completion of the dosing procedure based on a position of a stopper within the container. The module further has at least one temperature sensor configured for measuring a temperature of the medical fluid within the container based on a temperature of the container.
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公开(公告)号：US11628262B2
公开(公告)日：2023-04-18
申请号：US16210602
申请日：2018-12-05
摘要： Devices having male connectors for preventing connection to non-compatible female connectors are described. An exemplary male connector includes an elongate tip and a collar disposed coaxially around the elongate tip including a plurality of ribs disposed on either an inside surface or an outside surface of the collar for preventing entry of a non-compatible female connector into a channel formed between the elongate tip and the collar. One or more embodiments pertain to a device with a male connector and a compatible female connector including a threaded portion for engaging a corresponding threaded portion of the male connector.
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公开(公告)号：US20230115856A1
公开(公告)日：2023-04-13
申请号：US17958900
申请日：2022-10-03
摘要： A reservoir and drive assembly for a medical injector including a curved barrel having a first end and a second end positioned opposite the first end, with the curved barrel defining an interior space configured to receive a fluid, a stopper received within the interior space, with the stopper configured to move within the curved barrel to dispense fluid from the curved barrel, a curved plunger rod having a first end and a second end positioned opposite from the first end, with the curved plunger connected to the stopper, and at least one gear configured to drive the curved plunger rod and move the stopper within the curved barrel.
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公开(公告)号：US20230111548A1
公开(公告)日：2023-04-13
申请号：US17941758
申请日：2022-09-09
发明人： Nikolay Ivanov , Jorge Manzarraga
摘要： Aspects of the disclosure include systems for sorting particles of a sample in a flow stream (e.g., a biological sample containing cells). Systems according to certain embodiments include a flow cell configured to propagate a sample through a flow stream, a light source configured to irradiate particles of the sample in the flow stream, a photodetector configured to detect light from the irradiated particles and a support stage operationally coupled to the photodetector, where the support stage includes a closed-loop feedback position encoder that is configured to adjust position in the X-Y plane in response to a data signal generated by the photodetector in response to light from the irradiated particles. Methods for sorting particles using the subject systems are also described. Non-transitory computer readable storage medium are also provided.
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7.发明授权公开(公告)号：US11625829B2
公开(公告)日：2023-04-11
申请号：US17714875
申请日：2022-04-06
发明人： Matthew Bahr , Keegan Owsley
摘要： Disclosed herein include embodiments of a system, a device, and a method for sorting a plurality cells of a sample. A plurality of raw images comprising pixels of complex values in a frequency space can be generated from a plurality of channels of fluorescence intensity data of fluorescence emissions of fluorophores, the fluorescence emissions being elicited by fluorescence imaging using radiofrequency-multiplexed excitation in a temporal space. Spectral unmixing can be performed on the raw images prior to a sorting decision being made.
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公开(公告)号：US11617864B2
公开(公告)日：2023-04-04
申请号：US16774230
申请日：2020-01-28
发明人： Jonathan Karl Burkholz , Ralph L. Sonderegger , Bart D. Peterson , Bin Wang , Olivia Hu , Neville Chia
摘要： A compliant catheter adapter may include a catheter adapter body formed of a compliant material. The catheter adapter body may have a generally elongate shape and an inner chamber. The catheter adapter body may include a compression resistant septum disposed toward the proximal end of the catheter adapter body. The compression resistant septum may have a lumen configured to receive an elongate object. The compression resistant septum may also be coupled to a compression cap that imparts a compression force on the compression resistant septum such that the lumen narrows and seals when the elongate object is removed from the lumen.
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公开(公告)号：US20230086295A1
公开(公告)日：2023-03-23
申请号：US18059219
申请日：2022-11-28
摘要： Certain aspects relate to encryption systems and methods for medical devices. A medical device can include a connectivity module for establishing a communication channel with a cloud system. After obtaining a test result, the device can generate an unencrypted data block comprising a device identifier and an encrypted data block comprising a serial number of the device and the test result using an encryption key associated with the device identifier. The device can securely send the test result to the cloud system by transmitting the unencrypted data block and the encrypted data block to the cloud system via the communication channel.
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公开(公告)号：US11609176B2
公开(公告)日：2023-03-21
申请号：US17318608
申请日：2021-05-12
发明人： An-Dien Nguyen , Waheed Amiri , David J. Gianduzzo
摘要： Methods for evaluating performance a diode laser are provided. In embodiments, methods include receiving a laser beam profile of a diode laser, determining first, second and third laser beam widths at first, second and third laser intensities, respectively, for the laser beam profile, computing a first ratio between the second and third laser beam widths, computing a second ratio between the first and second laser beam widths, evaluating laser performance based on the first and second ratios, and outputting a determination regarding the suitability of the laser for use in a flow cytometry setting. Devices for practicing the subject methods are also provided, and include first and second stages configured to receive a diode laser and beam profiler, respectively. Aspects of the invention further include flow cytometers incorporating a diode laser that has been evaluated by the subject method.
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