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公开(公告)号：US20240222101A1
公开(公告)日：2024-07-04
申请号：US18577578
申请日：2022-05-06
发明人： Allen Hubbard , Shrikaar Kambhampati , Brad Evans
IPC分类号： H01J49/00
CPC分类号： H01J49/0036
摘要： Systems and methods for amplification and detection of metabolite signals are provided. A plurality of files containing m/z signal intensities may be captured by a mass spectrometer. Each file of m/z signal intensities may include signals associated with mass measurements of compounds in a respective sample. The datasets of the chromatograms may be combined into a merged spectra of m/z signal intensities. A concentration of signals may be identified in the merged chromatogram as following a specified statistical distribution and determined to be indicative of a metabolite when the concentration of signals corresponds to one or more mass measurements associated with a metabolite and an isotopologue of the metabolite.
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公开(公告)号：US20240041914A1
公开(公告)日：2024-02-08
申请号：US18450977
申请日：2023-08-16
发明人： Bala P. Venkata
IPC分类号： A61K31/713 , C12N15/113 , C12N15/82 , A01N63/60
CPC分类号： A61K31/713 , C12N15/113 , C12N15/8286 , A01N63/60 , C12N2310/14
摘要： Provided herein is the identification of insect RNAi target genes (IRTG) involved in gut microbial clearance and containment and examples of a novel biotechnology for devising pesticidal RNAi approaches.
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公开(公告)号：US20220098249A1
公开(公告)日：2022-03-31
申请号：US17310582
申请日：2020-02-07
发明人： Dilip M. Shah , Siva L.S. Velivelli
IPC分类号： C07K14/415 , A01N63/60 , C12N15/82
摘要： Antimicrobial nodule specific cysteine rich (NCR2) peptides and proteins are disclosed along with compositions comprising the NCR2 peptides or NCR2 proteins and transgenic or genetically edited plants or microorganisms that express the NCR2 peptides or proteins to inhibit growth of pathogenic microbes. Such NCR2 peptides, proteins, compositions, plants, and microorganisms can provide for inhibition of fungal and oomycete growth.
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公开(公告)号：US20220061333A1
公开(公告)日：2022-03-03
申请号：US17309920
申请日：2020-01-07
摘要： Antimicrobial nodule specific cysteine rich (NCR) peptides and proteins are disclosed along with compositions comprising the NCR peptides or NCR proteins and transgenic or genetically edited plants or microorganisms that express the NCR peptides or proteins to inhibit growth of pathogenic microbes. Such NCR peptides, proteins, compositions, plants, and microorganisms can provide for inhibition of fungal and oomycete growth.
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公开(公告)号：US11168331B2
公开(公告)日：2021-11-09
申请号：US16362346
申请日：2019-03-22
发明人： Xuemin Wang , Maoyin Li
IPC分类号： C12N15/82 , C12N9/20 , C07C69/604 , C12P7/64
摘要： Provided are plants that express, or overexpress, a pPLAIIIδ protein. Constitutive or seed-specific expression of pPLAIIIδ protein in Arabidopsis increases seed oil content, the amount of C20 and C22 fatty acids, and the amount of C56, C58, and C60 triacylglycerols, effectively resulting in significantly higher oil yield per plant. Use of pPLAIIIδ is therefore an effective biotechnological tool to significantly increase plant yield, including oil, and the amount of high value long chain fatty acids in agricultural and horticultural crops, especially oilseed crops.
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公开(公告)号：US10240163B2
公开(公告)日：2019-03-26
申请号：US14866125
申请日：2015-09-25
发明人： Xuemin Wang , Maoyin Li
IPC分类号： C12N15/82 , C12N9/20 , C07C69/604 , C12P7/64
摘要： Provided are plants that express, or overexpress, a pPLAIIIδ protein. Constitutive or seed-specific expression of pPLAIIIδ protein in Arabidopsis increases seed oil content, the amount of C20 and C22 fatty acids, and the amount of C56, C58, and C60 triacylglycerols, effectively resulting in significantly higher oil yield per plant. Use of pPLAIIIδ is therefore an effective biotechnological tool to significantly increase plant yield, including oil, and the amount of high value long chain fatty acids in agricultural and horticultural crops, especially oilseed crops.
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公开(公告)号：US20180340184A1
公开(公告)日：2018-11-29
申请号：US15769870
申请日：2016-10-21
发明人： Thomas P. Brutnell , Huang Pu
IPC分类号： C12N15/82 , C07K14/415
摘要： Compositions and methods for increasing plant growth for higher crop yield are provided. The methods involve the expression in a plant of interest of at least one C4 transporter coding sequence. Plants showing increased expression of one or more C4 transporter coding sequence of interest are encompassed by the invention. It is recognized that any method for increasing the expression of the C4 transporter coding sequences in a plant of interest can be used in the practice of the methods disclosed herein. Such methods include transformation, breeding and the like. Increased expression of the C4 transporter coding sequences in the plant of interest results in yield gains. Expression cassettes and vectors comprising the C4 transporter sequences disclosed herein are also provided herein. Methods for identifying genes under positive selection in plants that use C4 photosynthesis are disclosed and provided herein.
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公开(公告)号：US08153760B2
公开(公告)日：2012-04-10
申请号：US11795623
申请日：2006-01-17
申请人： Thomas J. Smith , Umesh C. Katpally
发明人： Thomas J. Smith , Umesh C. Katpally
CPC分类号： C07K14/005 , A61K39/00 , C12N2770/32722 , C12N2770/32734
摘要： The present invention relates generally to peptide vaccines. More specifically, the present invention relates to vaccines against rhinoviruses and other related and non-related pathogenic animal viruses. In addition, the present invention relates generally to methods of designing and producing vaccines against viruses and, in certain embodiments, against rhinoviruses and other pathogenic viruses.
摘要翻译： 本发明一般涉及肽疫苗。 更具体地，本发明涉及针对鼻病毒和其他相关和非相关病原性动物病毒的疫苗。 此外，本发明一般涉及设计和生产针对病毒的疫苗的方法，在某些实施方案中，针对鼻病毒和其它致病病毒。
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9.发明申请公开(公告)号：US20080196124A1
公开(公告)日：2008-08-14
申请号：US11741223
申请日：2007-04-27
申请人： Daniel P. Schachtman , Ryoung Shin
发明人： Daniel P. Schachtman , Ryoung Shin
CPC分类号： C12N15/8294 , C07K14/415 , C12N15/8238 , C12N15/8261 , C12N15/8274 , Y02A40/146
摘要： Methods for obtaining plants with decreased responses to auxins by reducing exprssion of endogenous MYB77 genes in plants are disclosed. Also disclosed are methods of using plant MYB77 transcriptional promoter sequences to drive expression of heterologous genes in select plant cells at select times in plant development. Methods of obtaining plants with decreased lateral root formation when grown under nutrient deficient conditions by reducing expression of endogenous MYB77 and transgenic plants with reduced expression of endogenous MYB77 genes in are also provided.
摘要翻译： 公开了通过减少植物中内源性MYB77基因的表达来获得对生长素反应降低的植物的方法。 还公开了使用植物MYB77转录启动子序列在植物发育中的选择时间驱动选择的植物细胞中异源基因的表达的方法。 还提供了通过减少内源MYB77的表达和在内源性MYB77基因的表达降低的转基因植物中在营养缺陷条件下生长时获得具有减少的侧根形成的植物的方法。
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公开(公告)号：US20240327905A1
公开(公告)日：2024-10-03
申请号：US18580984
申请日：2022-07-20
发明人： R. Keith Slotkin , Blake Meyers , Marianne Kramer
IPC分类号： C12Q1/6869 , C12N15/10 , C12Q1/6806 , C12Q1/6876
CPC分类号： C12Q1/6869 , C12N15/1096 , C12Q1/6806 , C12Q1/6876
摘要： Provided herein is an all-in-one-RNA sequencing assay that simultaneously delivers a qualitative characterization and quantitative measurement of selected RNAs. Also provided are various uses of the assay.
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