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1193 条记录 (耗时 0.027 秒)

    Liver Sinusoid Model
    3.
    发明申请
    Liver Sinusoid Model 审中-公开
    肝正弦模型

    公开(公告)号：US20130236972A1

    公开(公告)日：2013-09-12

    申请号：US13413679

    申请日：2012-03-07

    申请人： Hongseok Noh ,  Michael Bouchard

    发明人： Hongseok Noh ,  Michael Bouchard

    IPC分类号： C12N5/071 ,  C12M3/00

    CPC分类号： C12N5/067 ,  C12N2533/54 ,  C12N2535/00

    摘要： A liver sinusoid model includes a generally planar substrate having first and second generally parallel microchannels formed therein. A microporous membrane is disposed between and separating the first and second generally parallel microchannels. A first layer of cells lines one side of the membrane in the first microchannel. The first layer of cells are all a first common cell type. A second layer of cells extends parallel to the first layer of cells in one of the first microchannel and the second microchannel. The second layer of cells is all of a second common cell type. A liver sinusoid bioreactor utilizing the inventive model is also disclosed.

    摘要翻译： 肝窦状模型包括具有在其中形成的第一和第二大致平行的微通道的大致平面的基底。 微孔膜设置在第一和第二大致平行的微通道之间并分离。 第一层细胞在第一微通道中排列膜的一侧。 第一层细胞都是第一种细胞类型。 细胞的第二层平行于第一微通道和第二微通道之一中的第一细胞层延伸。 第二层细胞都是第二种细胞类型。 还公开了利用本发明模型的肝窦状生物反应器。

    BRAIDED ELECTRODES
    5.
    发明申请
    BRAIDED ELECTRODES 审中-公开
    BRAIDED电极

    公开(公告)号：US20090099441A1

    公开(公告)日：2009-04-16

    申请号：US12065697

    申请日：2006-09-08

    申请人： Simon Giszter ,  Frank K. Ko ,  Ubong Ime Udoekwere ,  Heejae Yang

    发明人： Simon Giszter ,  Frank K. Ko ,  Ubong Ime Udoekwere ,  Heejae Yang

    IPC分类号： A61N1/05 ,  A61B5/042

    CPC分类号： A61N1/0529 ,  A61N1/0551 ,  Y10T29/49194

    摘要： Electrodes for intracorporeal and other uses are provided. The invention features sterilizable, braided electrodes which are formed of or include conductive elements in electronic communication with a plurality of sites for electrical stimulation or sensing. Other active elements may be included in the braided electrodes.

    摘要翻译： 提供体内和其他用途的电极。 本发明的特征在于可灭菌的编织电极，其由多个用于电刺激或感测的部位电连接形成或包括导电元件。 编织电极中可以包括其它有源元件。

    Biomarker for cardiac transplant rejection
    6.
    发明申请
    Biomarker for cardiac transplant rejection 审中-公开
    心脏移植排斥的生物标志物

    公开(公告)号：US20080318247A1

    公开(公告)日：2008-12-25

    申请号：US12080285

    申请日：2008-04-02

    申请人： Chang Chang ,  Howard J. Eisen

    发明人： Chang Chang ,  Howard J. Eisen

    IPC分类号： G01N33/53 ,  C12Q1/02

    CPC分类号： G01N33/6893 ,  G01N2800/245

    摘要： The invention provides a method of diagnosing a disease or disorder featuring an abnormal level of a ring-containing molecule in a tissue. In one embodiment, a method of diagnosing organ transplant rejection is provided.

    摘要翻译： 本发明提供一种以组织中含环分子异常水平为特征的疾病或病症的诊断方法。 在一个实施例中，提供了一种诊断器官移植排斥的方法。

    SYSTEM AND METHOD FOR EVALUATING TISSUE
    7.
    发明申请
    SYSTEM AND METHOD FOR EVALUATING TISSUE 有权
    用于评估组织的系统和方法

    公开(公告)号：US20140058260A1

    公开(公告)日：2014-02-27

    申请号：US14031307

    申请日：2013-09-19

    申请人： Wan Y. SHIH ,  Wei-Heng SHIH ,  Hakki YEGINGIL ,  Ari D. BROOKS

    发明人： Wan Y. SHIH ,  Wei-Heng SHIH ,  Hakki YEGINGIL ,  Ari D. BROOKS

    IPC分类号： A61B8/08 ,  A61B8/00

    CPC分类号： A61B5/0053 ,  A61B5/4244 ,  A61B5/4312 ,  A61B5/4381 ,  A61B5/441 ,  A61B5/442 ,  A61B8/085 ,  A61B8/403 ,  A61B8/485 ,  G01N29/0672 ,  G01N2291/02475 ,  G01N2291/02827

    摘要： The present invention provides a sensor system for measuring an elastic modulus and a shear modulus and a method for using the sensor system to evaluate a tissue by determining the presence of and/or characterizing abnormal growths. The method involves applying a set of forces of different magnitudes to one or more locations of tissue, detecting the corresponding displacements due to said applied forces, determining the forces acting on those locations of tissue which are a combination of forces from the applied voltages and the countering forces from tissue deformation, obtaining the elastic modulus and/or shear modulus for a plurality of locations, and determining abnormal growth invasiveness, malignancy or the presence of a tumor from said elastic and/or shear moduli.

    摘要翻译： 本发明提供了一种用于测量弹性模量和剪切模量的传感器系统，以及使用该传感器系统通过确定异常生长的存在和/或表征异常生长来评估组织的方法。 该方法包括将一组不同大小的力施加到组织的一个或多个位置，检测由于所述施加的力引起的相应的位移，确定作用于组织的那些位置的力，其是来自所施加的电压和 组织变形的抵抗力，获得多个位置的弹性模量和/或剪切模量，以及从所述弹性和/或剪切模量确定异常生长侵袭性，恶性肿瘤或肿瘤的存在。

    METHOD AND APPARATUS FOR BRAIDING MICRO STRANDS
    8.
    发明申请
    METHOD AND APPARATUS FOR BRAIDING MICRO STRANDS 有权
    消除微观结构的方法和装置

    公开(公告)号：US20110277618A1

    公开(公告)日：2011-11-17

    申请号：US13129925

    申请日：2009-11-19

    申请人： Simon Giszter ,  Tae Gyo Kim ,  Arun Ramakrishnan

    发明人： Simon Giszter ,  Tae Gyo Kim ,  Arun Ramakrishnan

    IPC分类号： D04C1/00 ,  D04C3/00

    CPC分类号： D04C3/42

    摘要： A method and apparatus for fabricating microbraided structures is provided. A microbraiding device includes first and second carrier members that are movable with respect to each other. Each carrier includes a plurality of shelters. Spool-less strands of microfiber are retained in shuttles that are movable between the first and second shelters under magnetic forces. The microbraid structure is fabricated as the shuttles move between the first shelters, and as the first carrier member moves relative to the second carrier member.

    摘要翻译： 提供了一种用于制造微阵列结构的方法和装置。 微型装置包括可相对于彼此移动的第一和第二承载构件。 每个载体包括多个收容所。 无纺布的超细纤维束被保留在可在磁力下在第一和第二收容所之间移动的梭子中。 随着梭子在第一遮蔽物之间移动，并且当第一承载构件相对于第二承载构件移动时，制作微框架结构。

    RECONFIGURABLE INTELLIGENT SURFACE ANTENNA FOR RADIO FREQUENCY SIGNAL MITIGATION
    9.
    发明公开
    RECONFIGURABLE INTELLIGENT SURFACE ANTENNA FOR RADIO FREQUENCY SIGNAL MITIGATION 审中-公开

    公开(公告)号：US20240347918A1

    公开(公告)日：2024-10-17

    申请号：US18637741

    申请日：2024-04-17

    申请人： Drexel University

    发明人： Kyei Anim ,  Md Abu Saleh Tajin ,  Kapil R Dandekar

    IPC分类号： H01Q9/27 ,  H01Q5/25 ,  H04B7/04

    CPC分类号： H01Q9/27 ,  H01Q5/25 ,  H04B7/04013

    摘要： Reconfigurable intelligent surfaces (RISs) are an emerging transmission technology to aid wireless communication. However, the potential of using RIS to mitigate directed energy weapons (DEW) is not widely recognized. Described herein are RIS (based on spiral antenna elements) to aid the mitigation of high-energy radio-frequency (RF) sources applied to a DEW. For example, integrating a broadband circularly-polarized antenna system with RIS technology can successfully mitigate DEW attacks across a wide range of frequencies regardless of how radio waves are polarized. A spiral antenna is simulated that operates between 1.3 GHz and 7 GHz with a 3-dB axial ratio bandwidth (ARBW) covering 2 GHz-7 GHz. Full-wave simulation results show the potential promising application of RIS for the mitigation of DEW attacks.

    METHODS OF DIAGNOSING OR TREATING LYME DISEASE
    10.
    发明公开
    METHODS OF DIAGNOSING OR TREATING LYME DISEASE 审中-公开

    公开(公告)号：US20240288443A1

    公开(公告)日：2024-08-29

    申请号：US18640086

    申请日：2024-04-19

    申请人： Drexel University

    发明人： Mary Comunale ,  Benjamin Haslund-Gourley

    IPC分类号： G01N33/68 ,  A61K31/431 ,  A61K31/65 ,  A61K31/7036

    CPC分类号： G01N33/6854 ,  A61K31/431 ,  A61K31/65 ,  A61K31/7036 ,  G01N2440/38 ,  G01N2800/26 ,  G01N2800/56

    摘要： Described herein is a method of diagnosing Lyme disease in a subject. The method includes determining a glycosylation profile of a protein whose glycosylation profile is associated with Lyme disease in a subject, and comparing the glycosylation profile of the protein with a predetermined glycosylation profile of the protein indicating free of Lyme disease or a predetermined glycosylation profile of the protein indicating Lyme disease. Further described herein is a method of treating and/or ameliorating Lyme disease in a subject. The method includes diagnosing Lyme disease in a subject and, if the subject is diagnosed to have Lyme disease, administering to the subject an effective amount of compound effective for treating Lyme disease. Further described herein is a method of evaluating a treatment for Lyme disease. The method includes comparing a glycosylation profile of the patient with glycosylation profiles associated with successful/unsuccessful treatments.