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公开(公告)号:US20230235342A1
公开(公告)日:2023-07-27
申请号:US17821528
申请日:2022-08-23
发明人: ANDREW MARK CIGAN , SAVERIO CARL FALCO , HUIRONG GAO , MICHAEL LASSNER , DEREK JANTZ , ZHONGSEN LI , ZHAN-BIN LIU , SERGEI SVITASHEV , JAMES JEFFERSON SMITH
CPC分类号: C12N15/8202 , A01H1/06 , C12N9/22 , C12N15/8213
摘要: Methods for producing in a plant a complex transgenic trait locus comprising at least two altered target sequences in a genomic region of interest are disclosed. The methods involve the use of two or more double-strand-break-inducing agents, each of which can cause a double-strand break in a target sequence in the genomic region of interest which results in an alteration in the target sequence. Also disclosed are complex transgenic trait loci in plants. A complex transgenic trait locus comprises at least two altered target sequences that are genetically linked to a polynucleotide of interest. Plants, plant cells, plant parts, and seeds comprising one or more complex transgenic trait loci are also disclosed.
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公开(公告)号:US20230220407A1
公开(公告)日:2023-07-13
申请号:US18159396
申请日:2023-01-25
发明人: CLARA MARIA ALARCON , MATTHEW C. HARMON , M. ALEJANDRA PASCUAL , JAMES C. REGISTER, III , CHRISTOPHER J. SCELONGE , JOSHUA K. YOUNG , CATHY XIAOYAN ZHONG
IPC分类号: C12N15/82 , C12Q1/6895
CPC分类号: C12N15/8241 , C12N15/8286 , C12Q1/6895 , Y02A40/146
摘要: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-004114-3 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.
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公开(公告)号:US20220242839A1
公开(公告)日:2022-08-04
申请号:US17723614
申请日:2022-04-19
发明人: ALBERT LOREN CASALNUOVO , TY WAGERLE , JUN YAN , ERIN DEMKO , MATTHEW RICHARD OBERHOLZER , RAFAEL SHAPIRO
IPC分类号: C07D291/08 , C07C303/06 , C07D471/04
摘要: The present invention provides a method for preparing a compound of Formula C, Formula D, or Formula F: wherein each R1, R2, and R3 is independently H, SFs, N(C1-C8 alkyl)(C1-C8 alkyl), C(═S)N(C1-C8 alkyl)(C1-C8 alkyl), SO2N(C1-C8 alkyl)(C1-C8 alkyl), OSO2(C1-C8 alkyl), OSO2N(C1-C8 alkyl)(C1-C8 alkyl), N(C1-C8 alkyl)SO2(C1-C8 alkyl), or C1-C8 alkyl, C1-C8 haloalkyl, C2-C8 alkenyl, C2-C8 alkynyl, C3-C10 cycloalkyl, C3-C10 halocycloalkyl, C4-C10 alkylcycloalkyl, C4-C10 cycloalkylalkyl, C6-C14 cycloalkylcycloalkyl, C5-C10 alkylcycloalkylalkyl, C3-C8 cycloalkenyl, C1-C8 alkoxy, C1-C8 haloalkoxy, C3-C8 cycloalkoxy, C3-C8 halocycloalkoxy, C4-C10 cycloalkylalkoxy, C2-C8 alkenyloxy, C2-C8 alkynyloxy, C1-C8 alkylthio, C1-C8 alkylsulfinyl, C1-C8 alkylsulfonyl, C3-C8 cycloalkylthio, C3-C8 cycloalkylsulfinyl, C3-C8 cycloalkylsulfonyl, C4-C10 cycloalkylalkylthio, C4-C10 cycloalkylalkylsulfinyl, C4-C10 cycloalkylalkylsulfonyl, C2-C8 alkenylthio, C2-C8 alkenylsulfinyl, C2-C8 alkenylsulfonyl, C2-C8 alkynylthio, C2-C8 alkynylsulfinyl, C2-C8 alkynylsulfonyl, or phenyl; or
two of R1, R2, and R3 on adjacent ring atoms may be taken together to form a 5- to 7 -membered carbocyclic or heterocyclic ring, each ring containing ring members selected from carbon atoms and up to 3 heteroatoms independently selected from up to 2 O, up to 2 S, and up to 3 N, wherein up to 2 carbon atom ring members are independently selected from C(═O) and C(═S) and such ring is optionally substituted with up to 3 substituents independently selected from the group consisting of C1-C4 alkyl, C1-C4 haloalkyl, C2-C4 alkenyl, C2-C4 haloalkenyl, C2-C4 alkynyl, C2-C4 haloalkynyl, C3-C7 cycloalkyl, C3-C7 halocycloalkyl, C4-C8 alkylcycloalkyl, C4-C8 haloalkylcycloalkyl, C4-C8 cycloalkylalkyl, C4-C8 halocycloalkylalkyl, C1-C8 alkoxy, C1-C8 haloalkoxy, C2-C8 alkoxycarbonyl, C2-C6 haloalkoxycarbonyl, C2-C6 alkylcarbonyl and C2-C6 haloalkylcarbonyl; and
M is an inorganic cation or organic cation.-
公开(公告)号:US20220225560A1
公开(公告)日:2022-07-21
申请号:US17658202
申请日:2022-04-06
摘要: Methods and systems to improve application of seed applied components to seeds are disclosed. Environmentally controlled enclosures to test, evaluate and develop seed treatment solutions for certain geographical locations are provided. Controlled environments during seed treatment application process in a production location improves the overall seed treatment efficiency and uniformity.
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公开(公告)号:US11248233B2
公开(公告)日:2022-02-15
申请号:US16032228
申请日:2018-07-11
IPC分类号: C12N15/82
摘要: This invention relates to gene expression regulatory sequences, specifically transcription terminator sequences. Plant transcription terminator sequences are described herein. Methods for identifying novel plant transcription terminator sequences that can terminate transcription in one orientation or in a bidirectional manner and methods of using these terminator sequences to generate transgenic plants are described herein.
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公开(公告)号:US11142646B2
公开(公告)日:2021-10-12
申请号:US16084286
申请日:2017-03-20
发明人: Hiroyuki Sumi
IPC分类号: C09B67/08 , C09B67/46 , C09B5/60 , C08K5/00 , C08K5/3437 , C09B67/22 , G06F1/16 , C08K5/08 , C08L77/00 , C08K5/3465 , C08K5/375
摘要: This invention relates to a vehicle headlight assembly comprising: a light source, a housing supporting the light, a bezel equipped over the front side of the housing, and a transparent cover being equipped over the front side of the bezel, wherein the bezel and optionally the housing comprises a thermoplastic resin and a colorant, wherein the colorant is selected from the group consisting of an anthraquinone dye, an amine salt thereof and a mixture thereof.
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公开(公告)号:US20210309621A1
公开(公告)日:2021-10-07
申请号:US17281370
申请日:2019-10-02
发明人: ALBERT LOREN CASALNUOVO , TY WAGERLE , JUN YAN , ERIN DEMKO , MATTHEW RICHARD OBERHOLZER , RAFAEL SHAPIRO
IPC分类号: C07D291/08 , C07C303/06 , C07D471/04
摘要: The present invention provides a method for preparing a compound of Formula C, Formula D, or Formula F: wherein each R1, R2, and R3 is independently H, SF5, N(C1-C8 alkyl)(C1-C8 alkyl), C(═S)N(C1-C8 alkyl)(C1-C8 alkyl), SO2N(C1-C8 alkyl)(C1-C8 alkyl), OSO2(C1-C8 alkyl), OSO2N(C1-C8 alkyl)(C1-C8 alkyl), N(C1-C8 alkyl)SO2(C1-C8 alkyl), or C1-C8 alkyl, C1-C8 haloalkyl, C2-C8 alkenyl, C2-C8 alkynyl, C3-C10 cycloalkyl, C3-C10 halocycloalkyl, C4-C10 alkylcycloalkyl, C4-C10 cycloalkylalkyl, C6-C14 cycloalkylcycloalkyl, C5-C10 alkylcycloalkylalkyl, C3-C8 cycloalkenyl, C1-C8 alkoxy, C1-C8 haloalkoxy, C3-C8 cycloalkoxy, C3-C8 halocycloalkoxy, C4-C10 cycloalkylalkoxy, C2-C8 alkenyloxy, C2-C8 alkynyloxy, C1-C8 alkylthio, C1-C8 alkylsulfinyl, C1-C8 alkylsulfonyl, C3-C8 cycloalkylthio, C3-C8 cycloalkylsulfinyl, C3-C8 cycloalkylsulfonyl, C4-C10 cycloalkylalkylthio, C4-C10 cycloalkylalkylsulfinyl, C4-C10 cycloalkylalkylsulfonyl, C2-C8 alkenylthio, C2-C8 alkenylsulfinyl, C2-C8 alkenylsulfonyl, C2-C8 alkynylthio, C2-C8 alkynylsulfinyl, C2-C8 alkynylsulfonyl, or phenyl; or two of R1, R2, and R3 on adjacent ring atoms may be taken together to form a 5- to 7-membered carbocyclic or heterocyclic ring, each ring containing ring members selected from carbon atoms and up to 3 heteroatoms independently selected from up to 2 O, up to 2 S, and up to 3 N, wherein up to 2 carbon atom ring members are independently selected from C(═O) and C(═S) and such ring is optionally substituted with up to 3 substituents independently selected from the group consisting of C1-C4 alkyl, C1-C4 haloalkyl, C2-C4 alkenyl, C2-C4 haloalkenyl, C2-C4 alkynyl, C2-C4 haloalkynyl, C3-C7 cycloalkyl, C3-C7 halocycloalkyl, C4-C8 alkylcycloalkyl, C4-C8 haloalkylcycloalkyl, C4-C8 cycloalkylalkyl, C4-C8 halocycloalkylalkyl, C1-C8 alkoxy, C1-C8 haloalkoxy, C2-C8 alkoxycarbonyl, C2-C6 haloalkoxycarbonyl, C2-C6 alkylcarbonyl and C2-C6 haloalkylcarbonyl; and M is an inorganic cation or organic cation.
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公开(公告)号:US20210276280A1
公开(公告)日:2021-09-09
申请号:US16474292
申请日:2018-02-23
IPC分类号: B29C70/20
摘要: Voided carbon fiber tapes comprising from 18K to 125K carbon fibers, a thermoplastic resin having a viscosity of about 10 to about 150 Pa·s, at least 3 void areas, a fiber fraction ranging from about 35 to 70 percent, a void volume ranging from about 2 to about 50 percent, and at least 10 percent wetted carbon fibers may be used to prepare consolidated thermoplastic composites which exhibit flexural strengths greater than or equal to 75 percent of the theoretical flexural strength.
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公开(公告)号:US20210254095A1
公开(公告)日:2021-08-19
申请号:US17237489
申请日:2021-04-22
发明人: JENNIFER KARA BARRY , KEVIN HAYES , LU LIU , ERIC SCHEPERS , NASSER YALPANI
摘要: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
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10.
公开(公告)号:US11078315B2
公开(公告)日:2021-08-03
申请号:US16066535
申请日:2016-12-20
发明人: Ming-Hong Hung , Phan Linh Tang , Donald F. Lyons , Xudong Chen
IPC分类号: C08F226/06 , C08F214/26 , C08F214/22 , C08F214/28
摘要: Provided herein are copolymers that comprise copolymerized residues of a perfluorotrivinyltriazine monomer of Formula 1. Preferred Rf groups include, without limitation, —(CF2)n— (n=1-6); —(CF2)m—[OCF(CF3)CF2]p— (m=1-4, p=1-4); and —[(CF(CF3)—O)x—(CF2)k]— (x=1-3, k=1-5). Preferred comonomers for copolymerization with the perfluorotrivinyltriazine monomer (1) include, without limitation, tetrafluoroethylene (TFE); vinylidene fluoride (VF2); hexafluoropropylene (HFP); vinyl fluoride (VF); EVE; PSEPVE; perfluoro-(long chain vinyl ethers); E; P; PFBE; PEVE; EVE-OH; EVE-P; PDD; and the cure-site monomers BTFB, ITFB, 8-CNVE, 8-SAVE, and the like. Also provided are methods of synthesizing the copolymers and articles comprising the copolymers.
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