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公开(公告)号:US11554273B2
公开(公告)日:2023-01-17
申请号:US16900133
申请日:2020-06-12
IPC分类号: A61N5/10
摘要: The disclosure provides a phantom and method for quality assurance of a hadron therapy apparatus used in the intensity modulated particle therapy mode. The phantom comprises a frame structure comprising a base plate, one or more energy wedges, an energy wedge first face inclined with respect to said base plate and an energy wedge second face perpendicular to said base plate, said one or more energy wedges being mounted on said base plate, a 2D detector; said one or more wedges, and 2D detector being in known fixed positions in relation to said frame structure. Said phantom comprises in addition a Spread-Out Bragg Peak wedge, said SOBP wedge having an SOBP wedge first face inclined with respect to said base plate, and a SOBP wedge second face, perpendicular to said base plate, said SOBP wedge being made of a material having a relative density higher than 1.3 preferably 1.5, more preferably 1.7, the distance between the SOBP wedge first face and SOBP second face varying between the penetration depth of a beam having an energy between the high and low limit energy of the beam of said hadron therapy apparatus. The disclosure also provides a method for determining the compliance of the planned SOBP with the actual SOBP.
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公开(公告)号:US20210311212A1
公开(公告)日:2021-10-07
申请号:US17262066
申请日:2019-07-22
发明人: David Menichelli , Timo Hausbeck , Lutz Müller
摘要: The present disclosure relates to scintillating detector systems for radiation therapy beams. In one implementation, a detector system for evaluating radiation delivered by a radiation beam output from a beam generator may include a phantom enclosing an internal volume and having an outer surface, extending around the internal volume, for exposure to radiation, and an inner surface coated, at least in part, with a scintillating material and facing the internal volume. The system may further include a camera external to the enclosed volume and configured to view at least a portion of the inner surface, through an opening of the hollow phantom, when radiated by the radiation beam. The system may further include at least one processor configured to receive images from the camera and calculate, based on the received images, a spatial dose distribution produced by the radiation delivered by the radiation beam to the hollow phantom.
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公开(公告)号:US10743401B2
公开(公告)日:2020-08-11
申请号:US16698149
申请日:2019-11-27
发明人: Michel Abs , Jeremy Brison , Willem Kleeven
摘要: A vario-energy electron accelerator includes a resonant cavity consisting of a closed conductor, an electron source injecting a beam of electrons into the resonant cavity, an RF system coupled to the resonant cavity and generating an electric field in the resonant cavity, magnet units centred on a mid-plane and generating a field in a deflecting chamber in fluid communication with the resonant cavity, the magnetic field deflecting along a first deflecting trajectory of adding length an electron beam exiting the resonant cavity along a first radial trajectory to reintroduce it into the resonant cavity along a second radial trajectory, an outlet for extracting along an extraction path an accelerated electron beam from the resonant cavity towards a target, wherein at least one of the magnet units is adapted for modifying the first deflecting trajectory to a second deflecting trajectory, allowing a variation of the energy of the electron beam.
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公开(公告)号:US10600528B2
公开(公告)日:2020-03-24
申请号:US15998846
申请日:2018-08-17
发明人: Antero Abrunhosa , Vitor Alves , Francisco Alves
IPC分类号: G21G1/00 , B01J47/00 , B01J41/05 , G21G1/10 , C22B58/00 , C07B59/00 , B01J41/12 , B01J39/18 , B01J39/05 , A61K51/08
摘要: The present disclosure relates to a process for purifying and concentrating 68Ga isotope produced by irradiation with an accelerated particle beam of a 68Zn target in solution. The process according to the present disclosure allows for the production of pure and concentrated 68Ga isotope in hydrochloric acid solution. The present disclosure also relates to a disposable cassette for performing the steps of purification and concentration of the process.
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公开(公告)号:US20180318609A1
公开(公告)日:2018-11-08
申请号:US15968699
申请日:2018-05-01
发明人: Salih ARICAN , Christian VOGEL
IPC分类号: A61N5/10
摘要: This disclosure is related to an apparatus and method for commissioning or performing a quality assurance (QA) verification of a radiation therapy (RT) device. The device may comprise: (a) a motorised water phantom; (b) a RT controller configured for obtaining operation parameters of fields, and causing the RT device to emit a beam according to said operations parameters; (c) a QA controller having a memory for storing a measurements plan, the measurements plan including data defining a sequence of fields, and d) a reference radiation detector adapted and positioned for intercepting said radiation beam and for measuring the dose rate of said radiation beam. The reference radiation detector may be substantially transparent to the radiation beam. The QA controller may include an acquisition interface for acquiring and storing the dose rate from the reference radiation detector. The device may also include a processor configured to check the synchronism between the dose rate from the field radiation detector and the dose rate from the reference radiation detector.
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公开(公告)号:US20180099160A1
公开(公告)日:2018-04-12
申请号:US15727525
申请日:2017-10-06
发明人: Eric FORTON
CPC分类号: A61N5/1069 , A61B5/055 , A61N5/1039 , A61N5/1043 , A61N5/1049 , A61N5/1081 , A61N2005/1055 , A61N2005/1087 , G01R33/00 , G01R33/0213
摘要: The present disclosure relates to a particle therapy apparatus for irradiating a target with a charged particle beam and having a particle accelerator and an isocentric gantry rotatable about an axis. The gantry includes a sequence of bending magnets to successively bend and direct the particle beam towards the isocentre of the gantry. A last bending magnet of the sequence is configured to bend the particle beam in a first plane including the isocentre and making a large angle with the axis. The gantry further includes a first scanning magnet arranged upstream of the last bending magnet and configured to scan the particle beam over the target. The apparatus also includes a magnetic resonance imaging (MRI) system having two main magnet units arranged on both sides of the isocentre and configured to generate a main magnetic field parallel to or coaxial with the axis.
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公开(公告)号:US20180099159A1
公开(公告)日:2018-04-12
申请号:US15727503
申请日:2017-10-06
CPC分类号: A61N5/1069 , A61B6/03 , A61B6/0421 , A61N5/103 , A61N5/1037 , A61N5/1038 , A61N5/1049 , A61N5/1077 , A61N2005/1055 , A61N2005/1087
摘要: The present disclosure relates to an apparatus including a hadron therapy device and a magnetic resonance imaging device (MRI). The MRI may be an open MRI for acquiring magnetic resonance data in an MRI imaging volume. A nozzle of the apparatus may be fixed and positioned for directing a beam along a beam path substantially along an axis or substantially perpendicularly to the axis. The apparatus may further include a patient support system adapted for supporting a patient in a non-supine position in the MRI. The present disclosure also relates to methods for adapting a treatment plan to movements of organs resulting from displacement of a patient from a supine position in which treatment plan imaging was performed to a non-supine position in which a treatment will be performed.
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8.
公开(公告)号:US20180099154A1
公开(公告)日:2018-04-12
申请号:US15726836
申请日:2017-10-06
发明人: Damien PRIEELS
IPC分类号: A61N5/10
CPC分类号: A61N5/1039 , A61B5/055 , A61B5/4836 , A61B6/032 , A61B6/037 , A61B6/0478 , A61B6/4258 , A61B6/48 , A61B6/5205 , A61B6/5247 , A61B8/085 , A61N5/1049 , A61N5/1064 , A61N2005/1052 , A61N2005/1055 , A61N2005/1058 , A61N2005/1087
摘要: The present disclosure relates to a medical apparatus. In one implementation, the medical apparatus includes a hadron therapy device adapted for directing a hadron beam having an initial beam energy along a beam path to a target spot located inside a subject of interest; an MRI for acquiring a magnetic resonance (MR) image within an imaging volume having the target spot; a prompt-γ system adapted for acquiring a signal generated by the hadron beam; and a controller configured for computing an actual position of the Bragg peak of the hadron beam, based on the signal acquired by the PG system, and locating the actual position of the Bragg peak on the MR image.
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9.
公开(公告)号:US20180099153A1
公开(公告)日:2018-04-12
申请号:US15726681
申请日:2017-10-06
发明人: Damien PRIEELS
IPC分类号: A61N5/10
CPC分类号: A61N5/1039 , A61B5/055 , A61B5/4848 , A61B6/032 , A61B6/037 , A61B6/4092 , A61B6/4258 , A61N5/1049 , A61N5/1065 , A61N5/1081 , A61N2005/1052 , A61N2005/1055 , A61N2005/1061 , A61N2005/1087 , A61N2005/109 , G01N23/025 , G01N23/04
摘要: The present disclosure relates to a medical apparatus including a hadron therapy device directing an imaging hadron beam along a beam path. The beam path crosses a subject of interest including a plurality of tissues having upstream and downstream boundaries and a target tissue having a target spot. The apparatus further includes a magnetic resonance imaging device for acquiring magnetic resonance data within an imaging volume including a portion of the subject of interest including the target spot and at least the portion of the beam path between the upstream boundary and the target spot. The apparatus further includes a hadron radiography system (HRS) acquiring a signal generated by the imaging hadron beam and a controller for determining a water equivalent path length of the beam path between upstream and downstream boundaries based on at least the signal.
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10.
公开(公告)号:US09802061B2
公开(公告)日:2017-10-31
申请号:US14707828
申请日:2015-05-08
申请人: ION BEAM APPLICATIONS S.A. , Université Claude Bernard Lyon 1 , Institut National des Science Appliquées de Lyon , Centre National de Recherche Scientifique (CNRS)
CPC分类号: A61N5/1071 , A61B6/4216 , A61B6/4258 , A61B6/4291 , A61N5/1031 , A61N5/1043 , A61N5/1075 , A61N2005/1034 , A61N2005/1076 , A61N2005/1087 , G01T1/29
摘要: The disclosure is related to an apparatus and method for charged hadron therapy verification. The apparatus comprises a collimator comprising a plurality of collimator slabs of a given thickness, spaced apart so as to form an array of mutually slit-shaped openings, configured to be placed at a right angle to the beam line, so as to allow the passage of prompt gammas from the target, the collimator being defined at least by three geometrical parameters being the width and depth of the slit-shaped openings and a fill factor. The disclosure is also related to a method for charged hadron therapy verification with a multi-slit camera.
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