公开(公告)号：US20180238887A1

公开(公告)日：2018-08-23

申请号：US15307560

申请日：2015-04-27

Applicant: Korea University Research and Business Foundation

Inventor： Je Sang Ko ,  Hyoung-Tae An

IPC: G01N33/574 ,  C12Q1/6886 ,  A61P35/00 ,  G01N33/50

CPC classification number: G01N33/57411 ,  A61K31/7088 ,  A61P35/00 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N33/5011 ,  G01N2333/47

Abstract: The present invention relates to a pharmaceutical use of actinin-4 involved in the induction of cervical cancer and more specifically, characterizes actinin-4 as a marker protein capable of inducing cervical cancer, thereby providing the pharmaceutical use of actinin-4 that can be used in the diagnosis, prevention or treatment of cervical cancer.

公开(公告)号：US20240212800A1

公开(公告)日：2024-06-27

申请号：US18544488

申请日：2023-12-19

Applicant: LumanLab Inc. ,  Korea University Research and Business Foundation ,  Korea University Research and Business Foundation, Sejong Campus

Inventor： Jae Hyun LIM ,  Chul Hyun CHO ,  Seung Pil PACK

IPC: G16H10/20 ,  A61B5/16 ,  G16H50/20 ,  G16H50/30

CPC classification number: G16H10/20 ,  A61B5/16 ,  G16H50/20 ,  G16H50/30 ,  A61B2503/06

Abstract: An electronic device and a method to assess a mental health state of an adolescent by using a survey formed based on an artificial intelligence (AI). The method comprises: collecting physical information of a user through a pre-installed application, verifying survey questions regarding a mental health depending on the physical information, and verifying answers to the verified survey questions through the application; forming additional survey questions after having verified the answers and calculating a prediction rate of an appearance of symptoms of a mental illness regarding the additional survey questions by using AI models; verifying a set of survey questions including a plurality of sub-questions depending on the calculated prediction rate; outputting the verified set of survey questions through the application; outputting result data by adjusting the prediction rate; and transmitting the outputted result data.

公开(公告)号：US20220289657A1

公开(公告)日：2022-09-15

申请号：US17637565

申请日：2020-08-21

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS ,  KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Youngjoo BYUN ,  Hee Deung PARK ,  Sangjin NAM ,  Sang-Hyun SON ,  So Young HAM ,  Han Shin KIM

IPC: C07C49/255 ,  C07C49/248 ,  C07C49/235 ,  A61K31/12 ,  A61P31/04

Abstract: The present invention relates to a 4-gingerol derivative compound, or a racemate, isomer, or pharmaceutically acceptable salt thereof, the compound being capable of inhibiting biofilm formation and production of virulence factors. The 4-gingerol derivative compound according to the present invention has binding affinity to RhlR and corresponding RhlR antagonism activity that are significantly improved, and therefore can effectively inhibit biofilm formation and production of virulence factors. Furthermore, various bacterial infectious diseases caused by biofilms can be fundamentally prevented or treated by using a pharmaceutical composition comprising the 4-gingerol derivative compound, or a racemate, isomer, or pharmaceutically acceptable salt thereof as an active ingredient.

公开(公告)号：US20200283364A1

公开(公告)日：2020-09-10

申请号：US16632592

申请日：2018-07-19

Applicant: Korea University Research and Business Foundation, Sejong Campus ,  Korea University Research and Business Foundation

Inventor： Youngjoo BYUN ,  Hee-Deung PARK ,  Sang-Hyun SON ,  Eunji CHA ,  So-Young HAM ,  Hyunsuk CHOI

IPC: C07C49/255 ,  C07C49/245 ,  A61P31/04

Abstract: The present invention relates to a gingerol derivative having inhibitory activity against biofilm formation and a pharmaceutical composition for preventing or treating infections caused by biofilms including the gingerol derivative as an active ingredient. The gingerol derivative of the present invention exhibits significantly improved binding affinity for LasR and inhibitory activity against biofilm formation. Therefore, the gingerol derivative of the present invention can act on various membrane surfaces where biofilms tend to form and can effectively inhibit the formation of the corresponding biofilms. In addition, the use of the pharmaceutical composition according to the present invention can fundamentally prevent or treat a variety of infections caused by biofilms due to the presence of the gingerol derivative in the pharmaceutical composition.

公开(公告)号：US20180357419A1

公开(公告)日：2018-12-13

申请号：US15534708

申请日：2015-08-24

Applicant: Korea University Research and Business Foundation

Inventor： Kyung Ho Lee ,  Young In You ,  Seon Ju Kim ,  In Hyun Cho ,  Hyun Sik Yoon

IPC: G06F21/57

CPC classification number: G06F21/577 ,  G06F21/57 ,  G06F2221/034

Abstract: A method for measurement of an information-security-controlling status in accordance with the present disclosure includes receiving actual inspection data obtained by actually inspecting whether each domain complies with each security-controlling item, computing security-controlling status measurement scores for each domain on the basis of a significance grade of each control item, the degree of compliance with a corresponding control item, and a weighting set by a measurement manager, computing a final security-controlling status measurement score for a parent organization to which each domain belongs on the basis of an average of the security-controlling status measurement scores for each domain, and outputting the computed security-controlling status measurement scores and final security-controlling status measurement score.

公开(公告)号：US11964935B2

公开(公告)日：2024-04-23

申请号：US16632592

申请日：2018-07-19

Applicant: Korea University Research and Business Foundation, Sejong Campus ,  Korea University Research and Business Foundation

Inventor： Youngjoo Byun ,  Hee-Deung Park ,  Sang-Hyun Son ,  Eunji Cha ,  So-Young Ham ,  Hyunsuk Choi

IPC: C07C49/255 ,  A61P31/04 ,  C07C49/245

CPC classification number: C07C49/255 ,  A61P31/04 ,  C07C49/245

Abstract: The present invention relates to a gingerol derivative having inhibitory activity against biofilm formation and a pharmaceutical composition for preventing or treating infections caused by biofilms including the gingerol derivative as an active ingredient. The gingerol derivative of the present invention exhibits significantly improved binding affinity for LasR and inhibitory activity against biofilm formation. Therefore, the gingerol derivative of the present invention can act on various membrane surfaces where biofilms tend to form and can effectively inhibit the formation of the corresponding biofilms. In addition, the use of the pharmaceutical composition according to the present invention can fundamentally prevent or treat a variety of infections caused by biofilms due to the presence of the gingerol derivative in the pharmaceutical composition.

公开(公告)号：US11298534B2

公开(公告)日：2022-04-12

申请号：US16235498

申请日：2018-12-28

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION ,  Korea University Research and Business Foundation, Sejong Campus

Inventor： Hoon Jai Chun ,  Jung Hwa Hong ,  Dong Geun Sul ,  Bora Keum ,  Eun Sun Kim ,  Hyuk Soon Choi ,  Seung Han Kim

IPC: A61N1/00 ,  A61N1/36 ,  A61N1/372 ,  A61N1/05 ,  A61B17/00

Abstract: A stimulator for a digestive organ includes a case, a substrate member disposed in the case, and an electrode member connected to the substrate member and extending to protrude outwardly from the case. The electrode member may have a shape of a wire and may be configured to provide an electrical stimulation in a state of being inserted and fixed at a predetermined location within a digestive organ.

公开(公告)号：US20190321631A1

公开(公告)日：2019-10-24

申请号：US16235498

申请日：2018-12-28

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION ,  KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Hoon Jai Chun ,  Jung Hwa Hong ,  Dong Geun Sul ,  Bora Keum ,  Eun Sun Kim ,  Hyuk Soon Choi ,  Seung Han Kim

IPC: A61N1/36 ,  A61N1/372 ,  A61N1/05

Abstract: A stimulator for a digestive organ includes a case, a substrate member disposed in the case, and an electrode member connected to the substrate member and extending to protrude outwardly from the case. The electrode member may have a shape of a wire and may be configured to provide an electrical stimulation in a state of being inserted and fixed at a predetermined location within a digestive organ.

公开(公告)号：US20250062079A1

公开(公告)日：2025-02-20

申请号：US18724328

申请日：2022-11-21

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Wonjoon CHOI ,  Kyeong min KIM ,  Byung-Seok SEO

IPC: H01G11/24 ,  H01G11/26 ,  H01G11/32 ,  H01G11/46 ,  H01G11/86

Abstract: A composite according to an embodiment of the present invention is characterized by including a defect-induced carbon body and a metal oxide coupled to the carbon body. The composite according to an embodiment of the present invention induces defects in the carbon body, thereby improving interfacial properties between the carbon body and the metal oxide, and has an increased contact area, thereby improving electrochemical properties of the composite.

公开(公告)号：US12228567B2

公开(公告)日：2025-02-18

申请号：US17427413

申请日：2019-11-01

Applicant: Korea University Research and Business Foundation

Inventor： Dae Sung Yoon ,  Dong Tak Lee ,  In Su Kim ,  Gyu Do Lee ,  Hyo Gi Jung ,  Yong Hwan Kim

IPC: G01N33/543 ,  A61P25/28 ,  C12Q1/6816 ,  G01N33/68 ,  B82Y15/00 ,  B82Y30/00

Abstract: Disclosed are a colorimetric sensor kit for screening a therapeutic agent for a neurodegenerative disease, capable of easily detecting the degradation of amyloids by a drug, and a method for screening a therapeutic agent for a neurodegenerative disease.