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1.发明申请公开(公告)号：US20080278042A1
公开(公告)日：2008-11-13
申请号：US12009977
申请日：2008-01-23
申请人： Larry A. McCarthy , Robert E. Lloyd , D. Aaron Johnson , Robert A. Thibeault , Martin S. Rogers , Ronald W. Gingras , John Keith Campbell , Gene Klingbeil
发明人： Larry A. McCarthy , Robert E. Lloyd , D. Aaron Johnson , Robert A. Thibeault , Martin S. Rogers , Ronald W. Gingras , John Keith Campbell , Gene Klingbeil
CPC分类号： B01D46/0091 , B01D2265/04 , B01L1/04 , B01L2200/082 , B08B15/02
摘要： A biosafety cabinet includes one or more air filters below the work surface and a system for holding, sealing, replacing and disposing the air filters through the work access opening of the biosafety cabinet. The air filters under the work surface of the biosafety cabinet capture particulates entering the cabinet from the exterior environment and the particulates within the cabinet's work chamber. Instead of a mechanical clamp, the perimeter of the air filters are sealed using a gasket and a tape, eliminating the accumulation of the contaminants around mechanical clamps. The air filters may be accessed through the work access opening of the biosafety cabinet, packaged for disposal and removed from the biosafety cabinet without being exposed to the exterior environment. A filter cover with an adhesive surface is used to cover and lift the used, contaminated air filter within the biosafety cabinet.
摘要翻译： 生物安全柜包括一个或多个工作台下方的空气过滤器，以及通过生物安全柜的工作进入口保持，密封，更换和处理空气过滤器的系统。 生物安全柜的工作表面下的空气过滤器从外部环境中捕获进入机柜的微粒和机柜工作室内的微粒。 代替机械夹具，使用垫圈和胶带密封空气过滤器的周边，消除了机械夹具周围的污染物积聚。 空气过滤器可以通过生物安全柜的工作进入开口进入，包装处理，并从生物安全柜中取出，而不会暴露在外部环境中。 带有粘合剂表面的过滤器盖用于覆盖和提起生物安全柜内使用过的污染空气过滤器。
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公开(公告)号：US20080278041A1
公开(公告)日：2008-11-13
申请号：US11901581
申请日：2007-09-18
申请人： Robert E. Lloyd , D. Aaron Johnson , Robert A. Thibeault , Martin S. Rogers , Ronald W. Gingras , Scott R. Carpenter , Larry A. McCarthy
发明人： Robert E. Lloyd , D. Aaron Johnson , Robert A. Thibeault , Martin S. Rogers , Ronald W. Gingras , Scott R. Carpenter , Larry A. McCarthy
IPC分类号： B01L1/04
CPC分类号： B01L1/04 , B01L2200/082 , F24F3/1607 , F24F2011/0005
摘要： A biosafety cabinet includes at least one cable port disposed in a wall of the cabinet that allows small tubing and/or cables to enter the cabinet through the walls. The cable port eliminates problems associated with running the tubing and/or cables through an open door at the front of the cabinet. The cable ports enable the user to fully close the view screen door, while maintaining the ability to connect various tubes and/or cables to devices in the interior work area of the cabinet. The biosafety cabinet further includes a double wall configuration with negative pressure air space between the two walls. Air and byproducts or contaminants attempting to escape from the cabinet into the room or enter the cabinet from the outside environment is captured in the negative pressure area between the walls and transported directly to an air filter.
摘要翻译： 生物安全柜包括设置在机柜壁中的至少一个电缆端口，其允许小管道和/或电缆通过壁进入机柜。 电缆端口消除了通过机柜前部打开的门运行管道和/或电缆的问题。 电缆端口使用户能够完全关闭视窗门，同时保持将各种管和/或电缆连接到机柜内部工作区域中的设备的能力。 生物安全柜还包括在两个墙壁之间具有负压空气空间的双壁结构。 试图从柜体逃逸到室内或从外部环境进入机柜的空气和副产品或污染物被捕获在墙壁之间的负压区域中，并被直接输送到空气过滤器。
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3.发明授权公开(公告)号：US09095802B2
公开(公告)日：2015-08-04
申请号：US12009977
申请日：2008-01-23
申请人： Larry A. McCarthy , Robert E. Lloyd , D. Aaron Johnson , Robert A. Thibeault , Martin S. Rogers , Ronald W. Gingras , John Keith Campbell , Gene Klingbeil
发明人： Larry A. McCarthy , Robert E. Lloyd , D. Aaron Johnson , Robert A. Thibeault , Martin S. Rogers , Ronald W. Gingras , John Keith Campbell , Gene Klingbeil
CPC分类号： B01D46/0091 , B01D2265/04 , B01L1/04 , B01L2200/082 , B08B15/02
摘要： A biosafety cabinet includes one or more air filters below the work surface and a system for holding, sealing, replacing and disposing the air filters through the work access opening of the biosafety cabinet. The air filters under the work surface of the biosafety cabinet capture particulates entering the cabinet from the exterior environment and the particulates within the cabinet's work chamber. Instead of a mechanical clamp, the perimeter of the air filters are sealed using a gasket and a tape, eliminating the accumulation of the contaminants around mechanical clamps. The air filters may be accessed through the work access opening of the biosafety cabinet, packaged for disposal and removed from the biosafety cabinet without being exposed to the exterior environment. A filter cover with an adhesive surface is used to cover and lift the used, contaminated air filter within the biosafety cabinet.
摘要翻译： 生物安全柜包括一个或多个工作台下方的空气过滤器，以及通过生物安全柜的工作进入口保持，密封，更换和处理空气过滤器的系统。 生物安全柜的工作表面下的空气过滤器从外部环境中捕获进入机柜的微粒和机柜工作室内的微粒。 代替机械夹具，使用垫圈和胶带密封空气过滤器的周边，消除了机械夹具周围的污染物积聚。 空气过滤器可以通过生物安全柜的工作进入开口进入，包装处理，并从生物安全柜中取出，而不会暴露在外部环境中。 带有粘合剂表面的过滤器盖用于覆盖和提起生物安全柜内使用过的污染空气过滤器。
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公开(公告)号：US4305347A
公开(公告)日：1981-12-15
申请号：US144890
申请日：1980-04-29
IPC分类号： A01K1/03
CPC分类号： A01K1/031
摘要： A multi-level, animal inhalation toxicology research chamber system is disclosed. It has an enclosed airtight chamber defining a central enclosure with vertically extending inlet and outlet plenums at its opposite ends. A plurality of vertically spaced horizontally extending perforated shelves with underlying collection pans are provided for supporting laboratory animal cages vertically spaced on a plurality of levels. Air is distributed from the inlet plenum to the outlet plenum means through the animal cages in a horizontal direction. The collection pans prevent vertical fluid communication and the perforated shelves permit passage of animal waste into the collection pan, thereby preventing animals from contacting their own waste and preventing waste from falling on animals located beneath an upper cage.
摘要翻译： 公开了一个多层次的动物吸入毒理学研究室系统。 它具有封闭的气密室，其限定了在其相对端处具有垂直延伸的入口和出口增压室的中央外壳。 提供了多个垂直间隔开的水平延伸的具有底部收集盘的多孔架，用于支撑在多个水平面上垂直间隔开的实验室动物笼。 空气通过动物笼在水平方向从入口压力室分配到出口增压装置。 收集盘防止垂直的液体通信，并且穿孔的搁板允许动物废物通过收集盘，从而防止动物接触自己的废物并防止浪费物落在位于上笼下方的动物上。
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公开(公告)号：US08568516B2
公开(公告)日：2013-10-29
申请号：US13365027
申请日：2012-02-02
IPC分类号： B01D46/00
CPC分类号： B01D29/03
摘要： A biosafety cabinet device includes one or more walls forming a housing, a work area contained within the housing, a filter in fluid communication with the work area for filtering fluid passing through and exiting the work area. The filter includes a primary filtration surface through which a majority of fluid being filtered by the filter passes. A filter removal device is configured to couple to the filter. The filter removal device includes a rigid barrier layer and one or more handling mechanisms adjoined with the rigid barrier layer and extending distal to the rigid barrier layer. When the filter removal device is securely coupled to the filter, the rigid barrier layer extends substantially across a non-peripheral portion of the primary filtration surface of the filter and allows passage of fluid from the work area through the primary filtration surface of the filter.
摘要翻译： 生物安全柜装置包括形成壳体的一个或多个壁，容纳在壳体内的工作区域，与工作区域流体连通的过滤器，用于过滤通过和离开工作区域的流体。 过滤器包括主过滤表面，大部分被过滤器过滤的流体通过该过滤表面通过。 过滤器去除装置被配置为耦合到过滤器。 过滤器去除装置包括刚性阻挡层和与刚性阻挡层相邻并延伸到刚性阻挡层的远侧的一个或多个处理机构。 当过滤器去除装置牢固地联接到过滤器时，刚性阻挡层基本上跨过过滤器的主过滤表面的非周边部分延伸，并允许流体从工作区域通过过滤器的主过滤表面。
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公开(公告)号：US20090298405A1
公开(公告)日：2009-12-03
申请号：US12244234
申请日：2008-10-02
CPC分类号： F24F3/1607 , B08B15/023
摘要： A canopy for a biological cabinet includes a plurality of openings, referred to as ports, covered by air dampers and designed to open and close as needed to reduce an overall volume of air required during normal operation. If the building exhaust system attempts to pull more air than is supplied by the cabinet, the intake dampers will open to allow room air in through the intake ports, thus helping the cabinet to maintain an acceptable level of intake airflow at its front access opening. If the building exhaust system does not pull a sufficient amount of air, the outlet damper will open and let the cabinet exhaust air escape through the outlet port, thus enabling the cabinet to maintain an acceptable level of intake airflow at its front access opening. The canopy may also include an internal air baffle that helps to capture the cabinet exhaust air and direct it out through the opening connected to the building exhaust duct.
摘要翻译： 用于生物柜的盖子包括被称为端口的多个开口，被空气阻尼器覆盖并设计为根据需要打开和关闭，以减少在正常操作期间所需的总体积。 如果建筑物排气系统试图拉动比由柜提供的空气更多的空气，进气阻尼器将打开以允许通过进气口进入室内空气，从而帮助机柜在其前进开口处保持可接受的进气气流水平。 如果建筑物排气系统没有吸入足够的空气，出风口将打开，并且让柜子排出空气通过出口排出，从而使机柜在其前部开口处保持可接受的进气气流水平。 顶篷还可以包括内部空气挡板，其有助于捕获柜体废气并将其通过连接到建筑物排气管道的开口引出。
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公开(公告)号：US4735899A
公开(公告)日：1988-04-05
申请号：US710325
申请日：1985-03-11
CPC分类号： C12Q1/02 , Y10S435/81
摘要： Disclosed is a process and test kit for determining the reliability of a barrier to microorganism passage. In accordance with the process, a multiplicity of non-self replicating particles is introduced into a first gas volume, disposed on one side of a barrier to particle movement, and particle traps are placed in a second gas volume on the other side of the barrier. The particles carry a marker substance such as a toxin for a selected microorganism or a component needed for growth of a selected microorganism. The barrier is operated and the contents of the trap are assayed for the amount of the marker substance present in association with particles which crossed the barrier by adding the marker substance in the trap to a culture of the selected microorganism and detecting the effect of the marker substance on the culture. Finally, the results of the assay are compared to a standard to determine the number of trapped particles which crossed the barrier. The process is capable of detecting the presence of less than 10 and as few as a single one of the particles.
摘要翻译： 公开了用于确定微生物通过的屏障的可靠性的方法和测试试剂盒。 根据该方法，将多个非自复制颗粒引入第一气体体积中，该第一气体体积设置在阻挡颗粒运动的一侧，并且将颗粒捕集器置于屏障的另一侧上的第二气体体积中 。 颗粒携带用于所选择的微生物或所选微生物生长所需的成分的标记物质，例如毒素。 操作屏障并且通过将陷阱中的标记物质添加到所选择的微生物的培养物中并检测标记物的影响来测定捕获物的内容物与跨过障碍物的颗粒相关联的量存在 物质上的文化。 最后，将测定结果与标准物进行比较，以确定穿过屏障的捕获颗粒的数量。 该方法能够检测小于10的存在和仅一个颗粒的存在。
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