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    Detection of asynchrony
    2.
    发明授权
    Detection of asynchrony 有权
    检测异步

    公开(公告)号：US09392964B2

    公开(公告)日：2016-07-19

    申请号：US13264012

    申请日：2010-04-22

    申请人： Qestra Camille Mulqueeny ,  Stephen James Redmond ,  Nigel Hamilton Lovell

    发明人： Qestra Camille Mulqueeny ,  Stephen James Redmond ,  Nigel Hamilton Lovell

    IPC分类号： A61B5/087 ,  A61B5/091 ,  A61B5/085 ,  A61M16/00 ,  A61B5/00

    CPC分类号： A61M16/0066 ,  A61B5/085 ,  A61B5/087 ,  A61B5/091 ,  A61B5/7264 ,  A61M16/0003 ,  A61M16/0051 ,  A61M16/026 ,  A61M16/04 ,  A61M16/06 ,  A61M16/0875 ,  A61M2016/0027 ,  A61M2016/003 ,  A61M2016/0036 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2210/1014 ,  A61M2230/005 ,  A61M2230/42 ,  A61M2230/46 ,  A61M2230/65

    摘要： A controller or processor(s) (1112) implements detection of respiratory related conditions, such as asynchrony, associated with use of a respiratory treatment apparatus (1102) or ventilator. Based on data derived from sensor signals associated with the respiratory treatment, the detector may evaluate a feature set of detection values to determine whether or not an asynchrony occurs in a breath of the patient's respiratory cycle such as by comparing the values against a set of thresholds. Different events may also be identified based on the particular feature set and threshold(s) involved in the detection processing. Automated determination of feature sets may also be implemented to design different asynchrony event classifiers. The methodologies may be implemented by computers or by respiratory treatment apparatus. The detection of such asynchrony events can then also serve as part of control logic for automated adjustments to the control parameters of the respiratory treatment generated by the respiratory treatment apparatus.

    摘要翻译： 控制器或处理器（1112）实现与使用呼吸治疗设备（1102）或呼吸机相关联的呼吸相关状况（例如不同步）的检测。 基于从与呼吸治疗相关联的传感器信号导出的数据，检测器可以评估检测值的特征集合，以确定在患者的呼吸周期的呼吸中是否发生不同步，例如通过将值与一组阈值进行比较 。 也可以基于检测处理中涉及的特定特征集和阈值来识别不同的事件。 还可以实现特征集的自动确定以设计不同的异步事件分类器。 方法可以由计算机或呼吸治疗设备来实现。 因此，这种不同步事件的检测也可以作为用于自动调整由呼吸治疗装置产生的呼吸治疗的控制参数的控制逻辑的一部分。

    EMG-controlled ventilator and method for the operation thereof
    3.
    发明授权
    EMG-controlled ventilator and method for the operation thereof 有权
    EMG控制呼吸机及其操作方法

    公开(公告)号：US08646448B2

    公开(公告)日：2014-02-11

    申请号：US12597520

    申请日：2007-04-27

    申请人： Johan Lagerborg ,  Joakim Laksov

    发明人： Johan Lagerborg ,  Joakim Laksov

    IPC分类号： F16K31/02 ,  A61M16/00 ,  A62B7/00

    CPC分类号： A61B5/0488 ,  A61M16/0051 ,  A61M16/024 ,  A61M2210/1014 ,  A61M2230/60

    摘要： A ventilator provides breathing support to a patient in an EMG controlled mode, and has an input that receives an EMG signal representative of breathing activity from the patient and a control unit for controlling the ventilation in dependence of said EMG signal. The ventilator has a registration unit that registers the actual breathing support provided from the ventilator to the patient, and the control unit determines if there is asynchrony between the EMG signal and the breathing activity and, in case of asynchrony, causes a switch from EMG controlled ventilation to a second ventilation mode not dependent on the EMG signal. If synchrony is detected the ventilator can return to EMG controlled ventilation.

    摘要翻译： 呼吸机以EMG控制模式向患者提供呼吸支持，并且具有接收来自患者的代表呼吸活动的EMG信号的输入和用于根据所述EMG信号控制通气的控制单元。 呼吸机具有注册单元，其将从呼吸机提供的实际呼吸支持登记到患者，并且控制单元确定EMG信号和呼吸活动之间是否存在不同步，并且在异步的情况下导致从EMG控制的切换 通气至不依赖于EMG信号的第二通气模式。 如果检测到同步，呼吸机可以返回EMG控制的通气。

    Ventilator-initiated prompt regarding auto-PEEP detection during pressure ventilation
    4.
    发明授权
    Ventilator-initiated prompt regarding auto-PEEP detection during pressure ventilation 有权
    呼吸机启动提示在压力通气过程中自动PEEP检测

    公开(公告)号：US08607791B2

    公开(公告)日：2013-12-17

    申请号：US12827130

    申请日：2010-06-30

    申请人： Gary Milne ,  Kirk Hensley ,  Peter R. Doyle ,  Gardner Kimm

    发明人： Gary Milne ,  Kirk Hensley ,  Peter R. Doyle ,  Gardner Kimm

    IPC分类号： A61M16/00 ,  G06F3/00

    CPC分类号： A61M16/0063 ,  A61B5/08 ,  A61M16/0051 ,  A61M16/026 ,  A61M16/0833 ,  A61M2016/0021 ,  A61M2016/0027 ,  A61M2016/0036 ,  A61M2205/502 ,  A61M2205/505 ,  A61M2205/584 ,  A61M2210/1014 ,  A61M2230/20 ,  A61M2230/43 ,  A61M2230/46 ,  G06F19/00 ,  G16H40/63 ,  G16H50/20

    摘要： This disclosure describes systems and methods for monitoring and evaluating ventilatory parameters, analyzing ventilatory data associated with those parameters, and providing useful notifications and/or recommendations to clinicians. Modern ventilators monitor, evaluate, and graphically represent a myriad of ventilatory parameters. However, many clinicians may not easily identify or recognize data patterns and correlations indicative of certain patient conditions, changes in patient condition, and/or effectiveness of ventilatory treatment. Further, clinicians may not readily determine appropriate ventilatory adjustments that may address certain patient conditions and/or the effectiveness of ventilatory treatment. Specifically, clinicians may not readily detect or recognize the presence of Auto-PEEP during various types of pressure ventilation. According to embodiments, a ventilator may be configured to monitor and evaluate diverse ventilatory parameters to detect Auto-PEEP and may issue suitable notifications and recommendations to the clinician when Auto-PEEP is implicated. The suitable notifications and recommendations may further be provided in a hierarchical format.

    摘要翻译： 本公开描述了用于监测和评估通气参数的系统和方法，分析与这些参数相关联的通气数据，并向临床医生提供有用的通知和/或建议。 现代呼吸机监测，评估和图形化表示无数通气参数。 然而，许多临床医生可能不容易识别或识别指示某些患者状况，患者状况变化和/或通气治疗有效性的数据模式和相关性。 此外，临床医生可能不能容易地确定可以解决某些患者状况和/或通气治疗的有效性的适当的通气调节。 具体来说，临床医生在各种类型的压力通气期间可能不能容易地检测或识别Auto-PEEP的存在。 根据实施例，呼吸机可以被配置为监测和评估各种通气参数以检测自动PEEP，并且当涉及Auto-PEEP时可以向临床医生发布合适的通知和建议。 可以以分层格式进一步提供合适的通知和建议。

    Proportional pressure assist ventilation controlled by a diaphragm electromyographic signal
    6.
    发明授权
    Proportional pressure assist ventilation controlled by a diaphragm electromyographic signal 有权
    比例压力辅助通气由隔膜肌电信号控制

    公开(公告)号：US07661427B2

    公开(公告)日：2010-02-16

    申请号：US10405291

    申请日：2003-04-02

    申请人： Christer Sinderby ,  Jennifer Beck

    发明人： Christer Sinderby ,  Jennifer Beck

    IPC分类号： A61B5/04 ,  F16K31/02

    CPC分类号： A61B5/0492 ,  A61M16/0051 ,  A61M16/026 ,  A61M2210/1014 ,  A61M2230/08 ,  A61M2230/60 ,  Y10S128/925

    摘要： A closed loop system uses (a) the intensity of the diaphragm electromyogram (EMG) for a given inspiratory volume; (b) the inspiratory volume for a given EMG intensity; or (c) a combination of (a) and (b); in view of controlling the level of gas flow, gas volume or gas pressure delivered by a mechanical (lung) ventilator. The closed loop ventilator system enables for automatic or manual adjustment of the level of inspiratory support in proportion to changes in the neuro-ventilatory efficiency such that the neural drive remains stable at a desired target level. An alarm can also be used to detect changes in neuroventilatory efficiency in view of performing manual adjustments.

    摘要翻译： 闭环系统使用（a）给定吸气体积的隔膜肌电图（EMG）的强度; （b）给定EMG强度的吸气量; 或（c）（a）和（b）的组合; 考虑到控制由机械（肺）通气机输送的气体流量，气体体积或气体压力的水平。 闭环呼吸机系统能够与神经通气效率的变化成比例地自动或手动地调整吸气支持水平，使得神经驱动器保持稳定在期望的目标水平。 鉴于执行手动调整，报警器也可用于检测神经病效率的变化。

    Electromagnetic diaphragm assist device and method for assisting a diaphragm function
    7.
    发明申请
    Electromagnetic diaphragm assist device and method for assisting a diaphragm function 有权
    电磁隔膜辅助装置及辅助隔膜功能的方法

    公开(公告)号：US20070250162A1

    公开(公告)日：2007-10-25

    申请号：US11648908

    申请日：2007-01-03

    申请人： John Royalty

    发明人： John Royalty

    IPC分类号： A61M1/10

    CPC分类号： A61B5/0809 ,  A61F2002/043 ,  A61F2250/0001 ,  A61H31/02 ,  A61M2210/1014

    摘要： A diaphragm assist device includes a magnetic mat adapted for mounting inside a human body adjacent the diaphragm. The mat is made from a material responsive to application of an electromagnetic field so as to be movable into compressive relation with the diaphragm in response to application of the electromagnetic field thereto and movable out of the compressive relation to permit the diaphragm to relax when application of the electromagnetic field is discontinued. The device also includes an electromagnetic assembly adapted for surrounding the torso of the human body in functionally cooperative relation with respect to the mat, and for alternately generating and discontinuing the electromagnetic field so that the mat alternately moves into and out of the compressive relation with the diaphragm. The device also includes a controller constructed and arranged to control an intensity level of the electromagnetic field generated by the electromagnetic assembly.

    摘要翻译： 隔膜辅助装置包括适于安装在邻近隔膜的人体内的磁性垫。 该垫由响应于施加电磁场的材料制成，以响应于向其施加电磁场而移动成与隔膜的压缩关系，并且可移出压缩关系，以允许隔膜在施加 电磁场停止。 该装置还包括电磁组件，其适于围绕人体的功能性协调关系围绕人体躯干，并且用于交替地产生和中断电磁场，使得垫交替地移动到和/ 隔膜 该装置还包括构造和布置成控制由电磁组件产生的电磁场的强度水平的控制器。

    Target drive ventilation gain controller and method
    9.
    发明申请
    Target drive ventilation gain controller and method 审中-公开
    目标驱动通风增益控制器和方法

    公开(公告)号：US20060060190A1

    公开(公告)日：2006-03-23

    申请号：US11268117

    申请日：2005-11-07

    申请人： Christer Sinderby

    发明人： Christer Sinderby

    IPC分类号： A61M11/00 ,  A61M16/00

    CPC分类号： A61N1/05 ,  A61M16/026 ,  A61M2210/1014 ,  A61M2230/08 ,  A61M2230/60

    摘要： A gain controller and method for controlling the value of a gain is used in conjunction with an electrode array for detecting a signal representative of respiratory drive output of a patient during inspiration, and a lung ventilator for assisting inspiration of the patient. The gain controller comprises an input for receiving the signal representative of respiratory drive output; a comparator for determining whether the signal representative of respiratory drive output is higher or lower than a target drive signal; and a gain adjustment unit for increasing the value of a gain when the amplitude of the signal representative of respiratory drive output is higher than the amplitude of the target drive signal and for decreasing the value of this gain when the amplitude of the signal representative of respiratory drive output is lower than the amplitude of the target drive signal. The gain is applied to the signal representative of respiratory drive output to produce an amplified respiratory drive output representative signal used for controlling the lung ventilator. The advantage of target drive ventilation is that this mode of ventilation does not depend on pressure, flow or volume measurements. A leaky ventilatory line will introduce a change in respiratory drive which will change the ventilatory assist in order to return the respiratory drive to its target level. Also, changes in the patient's metabolic or patho-physiological status which result in altered respiratory drive will be compensated.

    摘要翻译： 用于控制增益值的增益控制器和方法与用于在吸气期间检测代表患者的呼吸驱动输出的信号的电极阵列结合使用，以及用于辅助患者的吸气的肺呼吸机。 增益控制器包括用于接收代表呼吸驱动输出的信号的输入端; 用于确定代表呼吸驱动输出的信号是否高于或低于目标驱动信号的比较器; 以及增益调整单元，用于当表示呼吸驱动输出的信号的幅度高于目标驱动信号的幅度时增加增益的值，并且当表示呼吸的信号的幅度时减小该增益的值 驱动输出低于目标驱动信号的幅度。 增益被应用于代表呼吸驱动输出的信号，以产生用于控制肺呼吸机的放大的呼吸驱动输出代表信号。 目标驱动器通风的优点在于这种通风方式不依赖于压力，流量或体积测量。 泄漏的通气线将引入呼吸驱动器的变化，这将改变通气辅助以使呼吸驱动器返回到其目标水平。 此外，患者代谢或病理生理状态的变化导致呼吸道传播改变将得到补偿。

    Proportional pressure assist ventilation controlled by a diaphragm electromyographic signal
    10.
    发明申请
    Proportional pressure assist ventilation controlled by a diaphragm electromyographic signal 有权
    比例压力辅助通气由隔膜肌电信号控制

    公开(公告)号：US20030226565A1

    公开(公告)日：2003-12-11

    申请号：US10405300

    申请日：2003-04-02

    发明人： Christer Sinderby ,  Jennifer Beck

    IPC分类号： A61M016/00

    CPC分类号： A61B5/0492 ,  A61M16/0051 ,  A61M16/026 ,  A61M2210/1014 ,  A61M2230/08 ,  A61M2230/60 ,  Y10S128/925

    摘要： A closed loop system uses (a) the intensity of the diaphragm electromyogram (EMG) for a given inspiratory volume; (b) the inspiratory volume for a given EMG intensity; or (c) a combination of (a) and (b); in view of controlling the level of gas flow, gas volume or gas pressure delivered by a mechanical (lung) ventilator. The closed loop ventilator system enables for automatic or manual adjustment of the level of inspiratory support in proportion to changes in the neuro-ventilatory efficiency such that the neural drive remains stable at a desired target level. An alarm can also be used to detect changes in neuroventilatory efficiency in view of performing manual adjustments.

    摘要翻译： 闭环系统使用（a）给定吸气体积的隔膜肌电图（EMG）的强度; （b）给定EMG强度的吸气量; 或（c）（a）和（b）的组合; 考虑到控制由机械（肺）通气机输送的气体流量，气体体积或气体压力的水平。 闭环呼吸机系统能够与神经通气效率的变化成比例地自动或手动地调整吸气支持水平，使得神经驱动器保持稳定在期望的目标水平。 鉴于执行手动调整，报警器也可用于检测神经病效率的变化。