公开(公告)号：US20180185518A1

公开(公告)日：2018-07-05

申请号：US15902081

申请日：2018-02-22

Applicant: FRANCO VITALIANO ,  GORDANA DRAGAN VITALIANO

Inventor： FRANCO VITALIANO ,  GORDANA DRAGAN VITALIANO

IPC: A61K49/00 ,  G02B6/122 ,  A61B5/00 ,  G01N21/64 ,  G01N21/552 ,  G01N21/65 ,  A61B18/04 ,  A61F2/82 ,  A61K31/661 ,  A61K41/00 ,  A61M31/00 ,  A61N1/44 ,  B82Y20/00 ,  B82Y30/00 ,  B82Y40/00 ,  A61N5/06 ,  A61F7/00 ,  B82Y5/00

CPC classification number: A61K49/005 ,  A61B5/0071 ,  A61B18/042 ,  A61F2/82 ,  A61F2007/0089 ,  A61K31/661 ,  A61K41/0042 ,  A61M31/002 ,  A61M2202/04 ,  A61M2202/064 ,  A61N1/44 ,  A61N2005/0656 ,  A61N2005/0659 ,  A61N2005/0661 ,  A61N2005/0663 ,  B82Y5/00 ,  B82Y20/00 ,  B82Y30/00 ,  B82Y40/00 ,  C07K2319/735 ,  G01N21/554 ,  G01N21/6428 ,  G01N21/648 ,  G01N21/658 ,  G02B6/1226

Abstract: The invention in suitable embodiments is directed to a method for cell energy therapeutics, the method comprising inducing an in vivo or in vitro cell to comprise an element for treating a disease, condition, or disorder. In one aspect, a composition comprising a source of energy and an isolated protein is for use in transforming a living cell into a therapeutic, a diagnostic, a sensor, a regenerative, or a cosmetic element for use in treating one or more type of disease, condition, or disorder.

公开(公告)号：US20180169279A1

公开(公告)日：2018-06-21

申请号：US15579093

申请日：2016-06-03

Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

Inventor： Gerhard RANDERS-PEHRSON ,  David Jonatha BRENNER ,  Alan BIGELOW

IPC: A61L2/10 ,  A61L2/00 ,  A61L2/26 ,  A61N5/06

CPC classification number: A61L2/10 ,  A61L2/0047 ,  A61L2/26 ,  A61L2202/11 ,  A61N5/0624 ,  A61N2005/0654 ,  A61N2005/0656 ,  A61N2005/0661 ,  A61N2005/0667

Abstract: Certain exemplary embodiments of the present disclosure can provide an apparatus and method for generating at least one radiation can be provided. The exemplary apparatus and/or method can selectively kill and/or affect at least one virus. For example, a radiation source first arrangement can be provided which is configured to generate at least one radiation having one or more wavelengths provided in a range of about 200 nanometers (nm) to about 230 nm, and at least one second arrangement can be provided which is configured to prevent the at least one radiation from having any wavelength that is outside of the range can be provided or which can be substantially harmful to cells of the body.

公开(公告)号：US20170258908A1

公开(公告)日：2017-09-14

申请号：US15600921

申请日：2017-05-22

Applicant: IMMUNOLIGHT, LLC

Inventor： Frederic A. BOURKE, JR.

IPC: A61K41/00 ,  A61F7/00 ,  A61H23/00 ,  A61K31/35 ,  A61K31/366 ,  A61K31/37 ,  A61K31/714 ,  A61K45/06 ,  A61K47/02 ,  A61N2/02 ,  A61N5/06 ,  A61N5/10

CPC classification number: A61K41/0071 ,  A61F7/00 ,  A61H23/00 ,  A61K31/35 ,  A61K31/366 ,  A61K31/37 ,  A61K31/714 ,  A61K41/00 ,  A61K41/0066 ,  A61K41/008 ,  A61K45/06 ,  A61K47/02 ,  A61N2/02 ,  A61N5/062 ,  A61N5/10 ,  A61N2005/0656 ,  A61N2005/1089 ,  A61N2005/1098 ,  A61K2300/00

Abstract: Methods for the treatment of a cell proliferation disorder in a subject, involving: (1) administering to the subject at least one activatable pharmaceutical agent that is capable of effecting a predetermined cellular change when activated, either alone or in combination with at least one energy modulation agent; and (2) applying an initiation energy from an initiation energy source to the subject, wherein the applying activates the activatable agent in situ, thus causing the predetermined cellular change to occur, wherein the predetermined cellular change treats the cell proliferation disorder, preferably by causing an increase or decrease in rate of cell proliferation, and a kit for performing the method, a computer implemented system for performing the method, a pharmaceutical composition useful in the method and a method for causing an autovaccine effect in a subject using the method.

公开(公告)号：US20170182333A1

公开(公告)日：2017-06-29

申请号：US15403568

申请日：2017-01-11

Applicant: Merck Patent GmbH

Inventor： Herwig BUCHHOLZ ,  Ewald AYDT ,  Junyou PAN

IPC: A61N5/06

CPC classification number: A61N5/0616 ,  A61M2037/0007 ,  A61N5/062 ,  A61N2005/0645 ,  A61N2005/0647 ,  A61N2005/0652 ,  A61N2005/0653 ,  A61N2005/0656 ,  A61N2005/0659 ,  A61N2005/0662 ,  A61N2005/0663

Abstract: The present invention relates, inter alia, to dermal systems comprising at least one light source and at least one pharmaceutically and/or cosmetically active ingredient. The dermal systems can be employed in order to enhance the penetration and action of the pharmaceutically and/or cosmetically active ingredient.

公开(公告)号：US09597527B2

公开(公告)日：2017-03-21

申请号：US13810322

申请日：2011-06-20

Applicant: Herwig Buchholz ,  Ewald Aydt ,  Junyou Pan

Inventor： Herwig Buchholz ,  Ewald Aydt ,  Junyou Pan

IPC: A61N5/06 ,  A61M37/00

CPC classification number: A61N5/0616 ,  A61M2037/0007 ,  A61N5/062 ,  A61N2005/0645 ,  A61N2005/0647 ,  A61N2005/0652 ,  A61N2005/0653 ,  A61N2005/0656 ,  A61N2005/0659 ,  A61N2005/0662 ,  A61N2005/0663

Abstract: Described is a dermal system which contains at least one light source and at least one pharmaceutically and/or cosmetically active ingredient. The dermal system can be employed in order to enhance the penetration and action of the pharmaceutically and/or cosmetically active ingredient. The at least one light source is a thin light source comprising at least one inorganic light emitting diode (LEDs) and/or at least one organic light emitting device.

公开(公告)号：US09352040B2

公开(公告)日：2016-05-31

申请号：US14245668

申请日：2014-04-04

Applicant: IMMUNOLIGHT, LLC.

Inventor： Frederic Avery Bourke, Jr.

IPC: A61K31/37 ,  A61K41/00 ,  A61K31/35 ,  A61K45/06 ,  A61K31/714 ,  A61K47/02 ,  A61F7/00 ,  A61H23/00 ,  A61K31/366 ,  A61N2/02 ,  A61N5/06 ,  A61N5/10

CPC classification number: A61K41/0071 ,  A61F7/00 ,  A61H23/00 ,  A61K31/35 ,  A61K31/366 ,  A61K31/37 ,  A61K31/714 ,  A61K41/00 ,  A61K41/0066 ,  A61K41/008 ,  A61K45/06 ,  A61K47/02 ,  A61N2/02 ,  A61N5/062 ,  A61N5/10 ,  A61N2005/0656 ,  A61N2005/1089 ,  A61N2005/1098 ,  A61K2300/00

Abstract: Methods for the treatment of a cell proliferation disorder in a subject, involving: (1) administering to the subject at least one activatable pharmaceutical agent that is capable of effecting a predetermined cellular change when activated, either alone or in combination with at least one energy modulation agent; and (2) applying an initiation energy from an initiation energy source to the subject, wherein the applying activates the activatable agent in situ, thus causing the predetermined cellular change to occur, wherein the predetermined cellular change treats the cell proliferation disorder, preferably by causing an increase or decrease in rate of cell proliferation, and a kit for performing the method, a computer implemented system for performing the method, a pharmaceutical composition useful in the method and a method for causing an autovaccine effect in a subject using the method.

Abstract translation: 用于治疗受试者的细胞增殖病症的方法，涉及：（1）向受试者施用至少一种可活化的药剂，其能够在活化时实现预定的细胞变化，单独或与至少一种能量组合 调制剂; 并且（2）将来自起始能量源的引发能量施加到受试者，其中所述施用在原位激活可活化试剂，从而引起预定的细胞变化，其中预定细胞变化治疗细胞增殖紊乱，优选通过引起 细胞增殖速率的增加或减少，用于实施该方法的试剂盒，用于实施该方法的计算机实施系统，用于该方法的药物组合物和使用该方法在受试者中引起自身疫苗效应的方法。

公开(公告)号：US20150157714A1

公开(公告)日：2015-06-11

申请号：US14567367

申请日：2014-12-11

Applicant: Nomir Medical Technologies, Inc.

Inventor： Eric BORNSTEIN

IPC: A61K41/00 ,  A61N5/06 ,  A61K47/46

CPC classification number: A61K41/0057 ,  A61K35/74 ,  A61N5/062 ,  A61N2005/0604 ,  A61N2005/0656 ,  A61K2300/00

Abstract: Systems and methods for treating a pathogenic bacterial infection are provided. The treatment may include introducing bioluminescent bacteria into a lung of a human or animal subject, and performing photodynamic therapy on the lung using light emitted from the bioluminescent bacteria.

Abstract translation: 提供了用于治疗病原菌感染的系统和方法。 治疗可以包括将生物发光细菌引入人或动物受试者的肺中，并使用从生物发光细菌发射的光对肺进行光动力学治疗。

公开(公告)号：US20150087685A1

公开(公告)日：2015-03-26

申请号：US14394064

申请日：2013-04-12

Applicant: Nitto Denko Corporation

Inventor： Sazzadur Rahman Khan ,  Shijun Zheng ,  Sheng Li ,  Amane Mochizuki ,  Keisaku Okada

IPC: A61K41/00 ,  A61N5/06

CPC classification number: A61K41/0071 ,  A61F9/0079 ,  A61F2009/00863 ,  A61F2009/00891 ,  A61K41/0061 ,  A61N5/0616 ,  A61N5/062 ,  A61N2005/0645 ,  A61N2005/0653 ,  A61N2005/0656 ,  A61N2005/0663 ,  C07D235/18 ,  C07D403/10 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1014 ,  C09K2211/1018 ,  C09K2211/1044 ,  H05B33/20

Abstract: Methods and devices related to the treatment of diseases using phototherapy are described. Some embodiments provide an organic light-emitting diode device, such as a light-emitting device for phototherapy, comprising Ring System 1, Ring System 2, Ring System 3, Ring System 4 or Ring System 5. Methods of treating disease with phototherapy are also described.

Abstract translation: 描述了使用光疗治疗疾病的方法和装置。 一些实施例提供了一种有机发光二极管装置，例如用于光疗的发光装置，包括环系统1，环系统2，环系统3，环系统4或环系统5.光疗治疗疾病的方法也是 描述。

公开(公告)号：US08478396B2

公开(公告)日：2013-07-02

申请号：US13552921

申请日：2012-07-19

Applicant: Yu-Chia Tsao ,  Yi-Wen Yang ,  Jung-Chien Chang

Inventor： Yu-Chia Tsao ,  Yi-Wen Yang ,  Jung-Chien Chang

IPC: A61N1/30

CPC classification number: A61K9/0097 ,  A61K9/7084 ,  A61N5/0616 ,  A61N2005/0645 ,  A61N2005/0656 ,  A61N2005/0659 ,  A61N2005/0662

Abstract: A phototherapy patch is disclosed, which includes: an adhesive layer, having a first surface and an opposite second surface; a pharmaceutical drug layer, disposed on the first surface of the adhesive layer; and a spontaneous emission layer, disposed over the pharmaceutical drug layer and capable of emitting therapeutic light by light illumination or a chemical reaction. Accordingly, the phototherapy patch according to the present invention has no power supply disposed therein, and thereby is suitable to be manufactured as a particularly thin and thus inconspicuous device.

Abstract translation: 公开了一种光疗贴片，其包括：具有第一表面和相对的第二表面的粘合剂层; 药物层，设置在粘合剂层的第一表面上; 以及设置在药物药物层上并能够通过光照射或化学反应发射治疗光的自发发射层。 因此，根据本发明的光疗贴片没有设置在其中的电源，因此适合制造为特别薄且因此不显眼的装置。

公开(公告)号：US20130116616A1

公开(公告)日：2013-05-09

申请号：US13810322

申请日：2011-06-20

Applicant: Herwig Buchholz ,  Ewald Aydt ,  Junyou Pan

Inventor： Herwig Buchholz ,  Ewald Aydt ,  Junyou Pan

IPC: A61N5/06

CPC classification number: A61N5/0616 ,  A61M2037/0007 ,  A61N5/062 ,  A61N2005/0645 ,  A61N2005/0647 ,  A61N2005/0652 ,  A61N2005/0653 ,  A61N2005/0656 ,  A61N2005/0659 ,  A61N2005/0662 ,  A61N2005/0663

Abstract: The present invention relates, inter alia, to dermal systems comprising at least one light source and at least one pharmaceutically and/or cosmetically active ingredient. The dermal systems can be employed in order to enhance the penetration and action of the pharmaceutically and/or cosmetically active ingredient.

Abstract translation: 本发明尤其涉及包含至少一种光源和至少一种药学和/或化妆品活性成分的皮肤系统。 可以使用真皮系统以增强药学和/或美容活性成分的渗透和作用。