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公开(公告)号：US12053565B2
公开(公告)日：2024-08-06
申请号：US16875889
申请日：2020-05-15
Applicant: Sorin Group Italia S.r.l.
Inventor： Adriano Mazzoli , Stefano Reggiani
CPC classification number: A61M1/1698 , A61M1/26 , A61M1/3623 , B01D63/031 , B01D63/034 , B01D2313/08 , B01D2313/19
Abstract: Described is a gas exchanger with a restriction element or elements to reduce gas exchange as desired to avoid hypo-capnia and hyper-oxygenation in small patients. The gas exchanger includes a gas exchanger housing with an outer wall and a core which defines an inner wall and having a blood inlet for receiving a blood supply and a blood outlet. The gas exchanger also includes: a hollow fiber bundle disposed within the housing between the core and the outer wall; and a gas inlet compartment for receiving an oxygen supply and directing the oxygen supply to first ends of the hollow fiber bundle, wherein the gas inlet compartment includes at least one restriction element configured to allow the oxygen supply to reach only a portion of the hollow fiber bundle.
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公开(公告)号：US20240358903A1
公开(公告)日：2024-10-31
申请号：US18765697
申请日：2024-07-08
Applicant: Sorin Group Italia S.r.l.
Inventor： Adriano Mazzoli , Stefano Reggiani
CPC classification number: A61M1/1698 , A61M1/26 , A61M1/3623 , B01D63/031 , B01D63/034 , B01D2313/08 , B01D2313/19
Abstract: Described is a gas exchanger with a restriction element or elements to reduce gas exchange as desired to avoid hypo-capnia and hyper-oxygenation in small patients. The gas exchanger includes a gas exchanger housing with an outer wall and a core which defines an inner wall and having a blood inlet for receiving a blood supply and a blood outlet. The gas exchanger also includes: a hollow fiber bundle disposed within the housing between the core and the outer wall; and a gas inlet compartment for receiving an oxygen supply and directing the oxygen supply to first ends of the hollow fiber bundle, wherein the gas inlet compartment includes at least one restriction element configured to allow the oxygen supply to reach only a portion of the hollow fiber bundle.
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公开(公告)号：US11884701B2
公开(公告)日：2024-01-30
申请号：US17203076
申请日：2021-03-16
Applicant: Merck Millipore Ltd.
Inventor： Damian Brellisford , Donna Lisa Crossley , Greg McIntosh , Robert Ruman , John Rydall , Christopher S. Shields
IPC: C07K1/22 , B01D63/08 , B01D69/10 , B01L3/00 , B01D63/02 , B01D63/10 , B01D63/14 , B01D69/02 , C07K14/77 , C07K16/00 , C12N9/36 , B01L9/00
CPC classification number: C07K1/22 , B01D63/024 , B01D63/034 , B01D63/082 , B01D63/087 , B01D63/10 , B01D63/14 , B01D69/02 , B01D69/106 , B01L3/502753 , C07K14/77 , C07K16/00 , C12N9/2462 , C12Y302/01017 , B01D2315/10 , B01D2325/36 , B01L9/527 , B01L2200/0647 , B01L2300/0681 , B01L2300/0803 , B01L2300/0816 , B01L2300/0887 , B01L2400/0409
Abstract: Described herein are fluid treatment devices for use in tangential flow filtration, comprising a housing unit and a composite material, wherein the composite material comprises: a support member comprising a plurality of pores extending through the support member; and a non-self-supporting macroporous cross-linked gel comprising macropores having an average size of 10 nm to 3000 nm, said macroporous gel being located in the pores of the support member. The invention also relates to a method of separating a substance from a fluid, comprising the step of placing the fluid in contact with an inventive device, thereby adsorbing or absorbing the substance to the composite material contained therein.
