公开(公告)号：US20180085024A1

公开(公告)日：2018-03-29

申请号：US15562547

申请日：2016-04-01

申请人： The General Hospital Corporation

发明人： Matthew S. Rosen ,  Mathieu Sarracanie ,  Najat Salameh

IPC分类号： A61B5/055 ,  G01R33/38 ,  G01R33/44 ,  G01R33/56 ,  G01V3/14 ,  G01R33/561

CPC分类号： A61B5/055 ,  G01R33/3806 ,  G01R33/381 ,  G01R33/445 ,  G01R33/5601 ,  G01R33/5614 ,  G01R33/5635 ,  G01V3/14

摘要： Systems and methods are provided for performing a medical imaging. The system includes a main magnet system configured to generate a main static magnetic field about at least a region of interest (ROD of a subject arranged in the main magnet system. The system also includes at least one gradient coil configured to establish at least one magnetic gradient field with respect to the main static magnetic field, The system also includes a radio frequency (RF) system configured to deliver excitation pulses to the subject. The system also includes a polarization magnet system configured to generate a polarization static magnetic field in an at least partially shielded region away from the main magnet system, the polarization magnet system configured to at least partially pre-polarize a blood substitute to be injected to the subject.

公开(公告)号：US20170322275A1

公开(公告)日：2017-11-09

申请号：US15144882

申请日：2016-05-03

申请人： Siemens Medical Solutions USA, Inc. ,  Emory University

发明人： Xiaodong Zhong ,  Deqiang Qiu ,  John Oshinski ,  Amit Saindane

IPC分类号： G01R33/483 ,  A61B5/03 ,  A61B5/00 ,  A61B5/055 ,  G01R33/561

CPC分类号： G01R33/4835 ,  A61B5/0013 ,  A61B5/0042 ,  A61B5/031 ,  A61B5/055 ,  A61B2576/026 ,  G01R33/5614 ,  G01R33/5616 ,  G01R33/5617 ,  G01R33/56333 ,  G01R33/5673

摘要： Embodiments relate to a magnetic resonance imaging (MRI) technique in which the two-dimensional (2D) Displacement Encoding with Stimulated Echoes (DENSE) imaging technique and the multiband technique are combined to provide a 2D multi-slice quantitative assessment of displacement, deformation, and mechanics indices of tissue. The scan time is equivalent to the short scan time of the conventional single slice 2D imaging while providing spatial volumetric coverage similar to three-dimensional (3D) imaging. The techniques are combined in both the sequence (i.e., data acquisition) and reconstruction sides. Quantification of tissue displacement and motion is achieved through the combination and further evaluation of tissue mechanical properties is provided by calculating different indices based on the displacement and motion values.

公开(公告)号：US20170281042A1

公开(公告)日：2017-10-05

申请号：US15506169

申请日：2015-10-09

申请人： University of Virginia Patent Foundation

发明人： Grady Wilson Miller ,  Yuan Zheng

IPC分类号： G01R33/48 ,  A61B5/01 ,  G01R33/561

CPC分类号： G01R33/4804 ,  A61B5/015 ,  A61B5/055 ,  A61B5/4836 ,  G01R33/5614

摘要： Some aspects of the present disclosure relate to systems and methods for magnetic resonance thermometry. In one embodiment, a preliminary balanced steady state free precession (bSSFP) magnetic resonance imaging pulse sequence is applied to an area of interest of a subject. Based on bSSFP image phases, a relationship between frequency and image phase associated with the area of interest can be determined and a bSSFP magnetic resonance imaging pulse sequence applied for temperature change measurement during and/or after focused energy is applied to the subject. Based on image phase change associated with temperature change and using the determined relationship between frequency and image phase, a change in the resonance frequency associated with the target area due to the application of the focused energy can be determined, and the temperature change can be determined based on the determined change in the resonance frequency.

公开(公告)号：US20170245807A1

公开(公告)日：2017-08-31

申请号：US15514323

申请日：2016-09-24

申请人： UNIVERSITY HEALTH NETWORK

发明人： Marshall Stephen SUSSMAN ,  Bernd Juergen WINTERSPERGER ,  Kai-Ho FOK ,  Issac Yiqun YANG

IPC分类号： A61B5/00 ,  G01R33/50 ,  A61B5/055 ,  G01R33/54

CPC分类号： A61B5/7278 ,  A61B5/0044 ,  A61B5/055 ,  A61B5/7207 ,  A61B2576/023 ,  G01R33/50 ,  G01R33/543 ,  G01R33/5614

摘要： Methods and systems for performing T1 mapping. T1 samples are obtained from an acquisition including one or more inversion groupings. The acquisition may be designed to result in incomplete tissue magnetization recovery between inversion groupings. The acquisition may be designed for the use of non-uniform, non-180° preparatory pulses. The method may also include the combined use of data from different inversion groupings. A model is used in which fit parameters are variable dependent on the inversion grouping.

公开(公告)号：US20170219672A1

公开(公告)日：2017-08-03

申请号：US15009412

申请日：2016-01-28

申请人： Toshiba Medical Systems Corporation

发明人： Mitsue MIYAZAKI ,  Aiming LU ,  Xiangzhi ZHOU

IPC分类号： G01R33/561 ,  G01R33/565 ,  G01R33/483 ,  G01R33/48 ,  G01R33/563

CPC分类号： G01R33/5614 ,  G01R33/4816 ,  G01R33/4818 ,  G01R33/482 ,  G01R33/4824 ,  G01R33/4826 ,  G01R33/4835 ,  G01R33/4838 ,  G01R33/56308 ,  G01R33/5635 ,  G01R33/56509

摘要： A magnetic resonance imaging method executed in a magnetic resonance imaging apparatus according to an embodiment comprises: applying an inversion pulse; executing a subsequent imaging sequence including an RF (Radio Frequency) pulse and a gradient magnetic field concurrently applied with the RF pulse in a slice direction and performing, for a slice position selected by the RF pulse and the gradient magnetic field and during a time period including a null point, data acquisition in a plurality of orientations including a center of a two-dimensional k-space.

公开(公告)号：US09618596B2

公开(公告)日：2017-04-11

申请号：US13540027

申请日：2012-07-02

申请人： Marcel Warntjes

发明人： Marcel Warntjes

IPC分类号： G01R33/50 ,  G01R33/561 ,  G01R33/563

CPC分类号： G01R33/50 ,  G01R33/5614 ,  G01R33/5616 ,  G01R33/56341

摘要： Magnetic resonance (MR) imaging methods and apparatus for simultaneous measurement of the physical properties R1 relaxation rate, R2 relaxation rate, proton density (PD), and apparent diffusion coefficient using a single magnetic resonance acquisition using a single gradient echo acquisition type. A method includes, from an MR scanner, obtaining at least three parallel, segmented gradient-echo acquisitions of a common acquisition type; in a computer, interleaving the at least three parallel, segmented gradient-echo acquisitions with a R1-sensitizing phase, a R2 sensitizing phase and a delay time; and in the computer, generating measures for R1 relaxation rate and R2 relaxation rate and PD from the at least three parallel, segmented gradient-echo acquisitions, thereby simultaneously estimating multiple physical parameters using the single gradient echo acquisition type.

公开(公告)号：US20160334487A1

公开(公告)日：2016-11-17

申请号：US15133907

申请日：2016-04-20

申请人： SIEMENS HEALTHCARE GMBH ,  UNIVERSITAETSSPITAL BASEL

发明人： OLIVER BIERI ,  TOM HILBERT ,  TOBIAS KOBER ,  GUNNAR KRUEGER ,  DAMIEN NGUYEN

IPC分类号： G01R33/561 ,  G01R33/50

CPC分类号： G01R33/5614 ,  G01R33/50 ,  G01R33/56536 ,  G01R33/56563

摘要： A method for improving image homogeneity of image data acquired from balanced Steady-State Free Precision (bSSFP) sequences in magnetic resonance imaging. Multiple bSSFP sequences are performed with different radio frequency phase increments to create multiple bSSFP image volumes with different phase offsets φ. Each image has voxels whose intensity M is a function of a nuclear resonance signal (or magnetization) measured by the MR imaging apparatus. Per-voxel fitting of a mathematical signal model onto the measured magnetization of the field of view in function of the phase offsets φ. Then the spin density M0, the relaxation time ratio Λ and the local phase offset Δφ are determined from the fit for each voxel. A homogeneous image of the object is generated by calculating the signal intensity in each voxel, using the spin density M0 and the relaxation time ratio Λ, wherein Δφ is chosen such that φ−Δφ=0°.

摘要翻译： 一种改善磁共振成像平衡稳态自由精确（bSSFP）序列获得的图像数据图像均匀性的方法。 以不同的射频相位增量执行多个bSSFP序列，以创建具有不同相位偏移φ的多个bSSFP图像体积。 每个图像具有其强度M是由MR成像装置测量的核共振信号（或磁化）的函数的体素。 将数学信号模型的每体素拟合到相位偏移函数φ的视场的测量磁化上。 然后根据每个体素的拟合确定自旋密度M0，弛豫时间比Λ和局部相位偏移Δφ。 通过使用自旋密度M0和弛豫时间比Λ计算每个体素中的信号强度来生成对象的均匀图像，其中选择Δφ使得φ-Δφ= 0°。

公开(公告)号：US20160007853A1

公开(公告)日：2016-01-14

申请号：US14325958

申请日：2014-07-08

申请人： General Electric Company

发明人： GLENN SCOTT SLAVIN

IPC分类号： A61B5/00 ,  G01R33/56 ,  G01R33/567 ,  G01R33/50 ,  A61B5/04 ,  A61B5/0456

CPC分类号： A61B5/0044 ,  A61B5/04012 ,  A61B5/0456 ,  A61B5/055 ,  A61B5/7292 ,  G01R33/50 ,  G01R33/5614 ,  G01R33/5673

摘要： A method for mapping T1 in myocardium includes selecting a recovery delay from EKG signal data; imposing a saturation pulse on the myocardium; waiting the recovery delay; and acquiring bSSFP data after the recovery delay.

摘要翻译： 用于在心肌中映射T1的方法包括从EKG信号数据中选择恢复延迟; 在心肌上施加饱和脉冲; 等待恢复延迟; 并在恢复延迟后获取bSSFP数据。

公开(公告)号：US09008753B2

公开(公告)日：2015-04-14

申请号：US13509273

申请日：2010-11-10

申请人： Daniel Messroghli

发明人： Daniel Messroghli

IPC分类号： A61B5/055 ,  G01R33/50 ,  G01R33/56 ,  G01R33/561 ,  G01R33/563 ,  G01R33/48 ,  G01R33/567

CPC分类号： G01R33/50 ,  A61B5/055 ,  G01R33/4818 ,  G01R33/4824 ,  G01R33/5602 ,  G01R33/5614 ,  G01R33/5619 ,  G01R33/56308 ,  G01R33/56325 ,  G01R33/5673

摘要： The present invention is directed to a method for use in conducting cardiac MR imaging which allows for reconstruction of T1 maps, cine images and IR-prepared images from one raw data set, wherein the method comprises the following steps: a) acquisition of raw data by use of an ECG-triggered, segmented, inversion recovery (IR) -prepared Look-Locker type pulse sequence for data acquisition, wherein the pulse sequence encompasses more than one shot, wherein each shot comprises: i) an ECG-triggered inversion pulse; ii) SSFP cine data acquisition of radial segmented profiles over more than one RR-interval for a predefined acquisition duration AD; and iii) a relaxation duration RD, during which no data is acquired; b) retrospective gating of raw data by sorting acquired raw data for each RR-interval into a pre-determined number of heart phases by definition of specific time windows within the RR-intervals and sampling of raw data acquired during the time windows respectively; c) image reconstruction, wherein the retrospectively gated raw data is used for reconstruction of T1 maps, cine images and/or IR-prepared images.

摘要翻译： 本发明涉及一种用于进行心脏MR成像的方法，其允许从一个原始数据集重建T1图，电影图像和IR准备的图像，其中该方法包括以下步骤：a）获取原始数据 通过使用用于数据采集的ECG触发的分段反转恢复（IR）准备型看门锁型脉冲序列，其中所述脉冲序列包含多于一个镜头，其中每个镜头包括：i）ECG触发反转脉冲 ; ii）对于预定义的采集持续时间AD，在多于一个RR间隔上的径向分段轮廓的SSFP电影数据采集; 以及iii）松弛持续时间RD，在此期间不获取数据; b）通过定义RR间隔内的特定时间窗口并分别在时间窗口期间获取的原始数据的采样，将每个RR间隔的获取的原始数据分类为预定数量的心脏阶段，回顾性地选择原始数据; c）图像重建，其中追溯门控的原始数据用于重建T1地图，电影图像和/或IR准备的图像。

公开(公告)号：US08866478B2

公开(公告)日：2014-10-21

申请号：US13181868

申请日：2011-07-13

申请人： Elfar Adalsteinsson ,  Hans-Peter Fautz ,  Kawin Setsompop ,  Lawrence Wald

发明人： Elfar Adalsteinsson ,  Hans-Peter Fautz ,  Kawin Setsompop ,  Lawrence Wald

IPC分类号： G01V3/00 ,  G01R33/565 ,  G01R33/561 ,  G01R33/56 ,  G01R33/44

CPC分类号： G01R33/56563 ,  G01R33/446 ,  G01R33/5607 ,  G01R33/5612 ,  G01R33/5614

摘要： In a magnetic resonance apparatus and operating method therefor, and in a processor that is programmed to design RF pulses for operating such a magnetic resonance apparatus, the RF pulses are designed to mitigate off-resonance effects caused by inhomogeneity of the basic (B0) magnetic field in the magnetic resonance apparatus. The RF pulses of a parallel transmit array are designed with different spatial phase distributions, that deviate from a constant phase from pulse-to-pulse, with the absolute value of the difference between respective spatial phase distributions of any two successively radiated RF pulses corresponding to the off-resonance that is caused by B0-inhomogeneity during the time between the radiation of the successive pulses. Additionally, or separately, currents supplied to the shim coils can be taken into account in the design of the RF pulses as an additional degree of freedom, with the shimming of the basic magnetic field produced by the shim currents deviating from shim currents designed to ideally produce a homogenous B0 field.

摘要翻译： 在一种磁共振装置及其操作方法中，并且在被编程为设计用于操作这种磁共振装置的RF脉冲的处理器中，RF脉冲被设计成减轻由基本（B0）磁性的不均匀性引起的非共振效应 磁场。 平行发射阵列的RF脉冲被设计为具有不同的空间相位分布，其偏离了脉冲到脉冲的恒定相位，对应于任何两个相继辐射的RF脉冲的相应空间相位分布之间的差的绝对值 在连续脉冲的辐射期间由B0不均匀性引起的非共振。 此外，或者单独地，作为附加自由度，在RF脉冲的设计中可以考虑提供给垫片线圈的电流，同时由偏置电流产生的基本磁场的匀场偏离设计成理想的电流 产生均匀的B0场。