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1.
公开(公告)号:US20240342278A1
公开(公告)日:2024-10-17
申请号:US18523203
申请日:2023-11-29
申请人: Omeros Corporation
发明人: W. Jason Cummings , Gregory A. Demopulos , Thomas A. Dudler , Larry W. Tjoelker , Christi L. Wood , Munehisa Yabuki
IPC分类号: A61K39/395 , B82Y25/00 , C01F17/206 , C07K16/40 , C09K11/77 , C12N9/64 , H01F1/00 , A61K39/00
CPC分类号: A61K39/3955 , B82Y25/00 , C01F17/206 , C07K16/40 , C09K11/77 , C09K11/7728 , C12N9/6424 , C12Y304/21104 , H01F1/0054 , A61K39/00 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C01P2002/54 , C01P2002/84 , C01P2004/64 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/734 , C07K2317/76 , C07K2317/90 , C07K2317/92
摘要: The present invention relates to MASP-3 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-3 dependent complement activation.
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2.
公开(公告)号:US20230395289A1
公开(公告)日:2023-12-07
申请号:US18251173
申请日:2021-11-25
CPC分类号: H01F1/0054 , H01F1/0063 , C08J5/005 , C08J5/249
摘要: Provided is the use of a magnetic nanocomposite material that is capable of polymerising an anaerobic adhesive or other monomeric materials in need thereof as a nanoinitiator, in said polymerisation. Also disclosed herein is a method of manufacturing the magnetic nanocomposite material. In a preferred embodiment, the nanoinitiator is a magnetic nanoparticle core covered with a shell bearing dendrons that chelate an initiating metal ion of copper.
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公开(公告)号:US20230330273A1
公开(公告)日:2023-10-19
申请号:US18336797
申请日:2023-06-16
发明人: Giovanni BALDI , Costanza RAVAGLI , Mauro COMES FRANCHINI , Mario Milco D'ELIOS , Marisa BENAGIANO , Marco BITOSSI
CPC分类号: A61K49/186 , H01F1/0054 , A61K49/1857 , A61K9/1075 , A61K9/20 , A61K9/5031 , A61K9/5089 , A61K41/0052 , H01F1/0063
摘要: There are described magnetic nanoparticles the surface of which is functionalized with catechol and constructs comprising a plurality of said nanoparticles encapsulated in a biocompatible polymer matrix, wherein a molecule with therapeutic action is optionally dispersed, said polymer matrix optionally being in turn further functionalized; there are further described cells of the immune system incorporating said polymeric constructs giving rise to their engineering.
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公开(公告)号:US20190206598A1
公开(公告)日:2019-07-04
申请号:US16226651
申请日:2018-12-20
发明人: Chien-An Chen , Cheng-Tai Chen , Pei-Shin Jiang
CPC分类号: H01F1/26 , G01N33/5434 , H01F1/0054 , H01F1/37
摘要: Described herein is a magnetic particle, which includes a knobby copolymer core, a polymer layer, a magnetic substance layer and a silicon-based layer. The polymer layer covers the knobby copolymer core and has at least one functional group. In addition, the magnetic substance layer covers the polymer layer and the silicon-based layer covers the magnetic substance layer. Furthermore, a manufacturing method of the magnetic particle is also described.
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公开(公告)号:US20190195706A1
公开(公告)日:2019-06-27
申请号:US16235881
申请日:2018-12-28
申请人: Sakhrat Khizroev , Rakesh Guduru , Dwayne McDaniel
发明人: Sakhrat Khizroev , Rakesh Guduru , Dwayne McDaniel
IPC分类号: G01L1/24 , H01F1/34 , H01F27/255 , H01F27/28 , G02B27/28 , G01L1/12 , H01F1/00 , H01L41/187
CPC分类号: G01L1/247 , G01L1/12 , G01M5/0091 , G01M11/005 , G02B27/288 , H01F1/0045 , H01F1/0054 , H01F1/344 , H01F27/255 , H01F27/2804 , H01L41/1132 , H01L41/1871
摘要: Systems for screening and health monitoring of materials are provided. The system can include a material embedded with magneto-electric nanoparticles (MENs), a laser configured to direct incident laser light waves at a target area of the material, an optical filter disposed between the laser and the material, and an analyzer configured to detect the laser light reflected from the material.
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公开(公告)号:US20180261363A1
公开(公告)日:2018-09-13
申请号:US15762706
申请日:2016-09-26
申请人: LG Chem, Ltd.
发明人: Jin Kyu Lee , Sang Bum Ahn
CPC分类号: H01F1/0054 , B22F1/02 , B22F3/105 , B29C67/00 , B33Y10/00 , B33Y50/02 , B33Y70/00 , C01G49/02 , C01P2004/62 , C01P2004/64 , C01P2006/42 , C08J5/005 , C08J2300/24 , C08K5/00 , C08L101/00 , H01F1/37 , H01F41/02
摘要: The present application relates to a composition for 3D printing, a 3D printing method using the same, and a three-dimensional shape comprising the same, and provides a composition for 3D printing capable of embodying a precise formation of a three-dimensional shape using a ceramic material and a uniform curing property of the three-dimensional shape.
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公开(公告)号:US20180230607A1
公开(公告)日:2018-08-16
申请号:US15950133
申请日:2018-04-10
摘要: The present invention is directed to composite nanoparticles comprising a metal, a rare earth element, and, optionally, a complexing ligand. The invention is also directed to composite nanoparticles having a core-shell structure and to processes for preparation of composite nanoparticles of the invention.
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公开(公告)号:US10005677B2
公开(公告)日:2018-06-26
申请号:US14404575
申请日:2013-05-31
发明人: Gil Lee , Mark Platt , James O'Mahony
IPC分类号: A61K9/51 , C01G49/02 , A61K9/50 , B01J13/04 , B01J13/12 , H01F1/00 , B01F3/08 , B01F3/22 , B01F7/00 , B01F15/02 , A61B5/055 , B01F15/06
CPC分类号: C01G49/02 , A61B5/055 , A61K9/5094 , B01F3/0811 , B01F3/0853 , B01F3/223 , B01F7/00 , B01F15/0203 , B01F2015/062 , B01J13/043 , B01J13/125 , C01P2004/61 , C01P2006/42 , H01F1/0054
摘要: There is provided a method of producing microparticles using an emulsion based synthesis route including: Providing a first fluid phase and a second fluid phase, wherein the first fluid phase is a continuous phase and the second fluid phase is a dispersed phase comprising a dispersed material, wherein the continuous phase is immiscible with the dispersed phase; Mixing the first continuous phase and the second dispersed phase in the presence of a surfactant in a shear device to form an emulsion of droplets of controllable size and having a narrow drop size distribution; Drying the emulsion to form microparticles of controllable size and having narrow size distribution, and wherein the microparticles may comprise spherical, crumpled, dimpled, porous or hollow microparticles morphology. Also provided is a system including shear device and drying arrangement. Also provided are micro particles of controllable size and morphology formed by the method.
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公开(公告)号:US20180151278A1
公开(公告)日:2018-05-31
申请号:US15520581
申请日:2015-10-23
申请人: CORNING INCORPORATED
发明人: Ann MeeJin Ferrie , Yan Jin , Lingyan Wang , Yue Zhou
CPC分类号: H01F1/12 , C12N15/1013 , H01F1/0054 , H01F1/20 , H01F1/344 , H01F1/36
摘要: Magnetic particles (100) have a particle size (134) of 500 nm or less and include a core (110) and a polymer coating (120) that surrounds and encapsulates the core (110). The core (110) includes a metal, metal alloy, or metal oxide of at least one metal such as B, Mg, Al, Mn, Co, Ni, Cu, Fe Sm, Yb, Dy, Gd or Er and Nb. The magnetic core (100) is a polycrystalline particle and is a superspin glass magnetic material, having a coercivity greater than zero and a magnetic remenance greater than zero at room temperature. Above room temperature and at low field, the magnetic moment of these superspin glass magnetic materials increases with temperature. An in situ hydrolysis/precipitation method from precursor metal salts is used to form the polymer-encapsulated magnetic particles (100).
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公开(公告)号:US20180108375A1
公开(公告)日:2018-04-19
申请号:US15561397
申请日:2016-02-08
申请人: Sony Corporation
发明人: Eiji NAKASHIO , Minoru YAMAGA , Jun TAKAHASHI
IPC分类号: G11B5/584 , G11B5/706 , G11B5/712 , G11B5/714 , G11B5/738 , H01F1/00 , H01F1/055 , H01F1/059
CPC分类号: G11B5/584 , G11B5/70615 , G11B5/70621 , G11B5/712 , G11B5/714 , G11B5/72 , G11B5/735 , G11B5/738 , H01F1/0054 , H01F1/0551 , H01F1/059
摘要: A magnetic recording medium includes a support, a recording layer, and a protective layer provided on at least one surface of the support and containing plate-shaped particle powder. The plate-shaped particle powder is stacked in an overlapping manner in a thickness direction of the protective layer such that main surfaces of plate-shaped particles face a surface of the support, and the plate-shaped particles have an average plate ratio of 60 or more.
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