公开(公告)号：US10987510B2

公开(公告)日：2021-04-27

申请号：US16417524

申请日：2019-05-20

申请人： SAGE PRODUCTS, LLC

发明人： Brian J. Fahey

IPC分类号： A61N1/04 ,  A61N1/36 ,  A61B5/0492 ,  A61H39/00 ,  A61B5/00 ,  A61B90/00

摘要： A method of electrically stimulating a target muscle of a patient includes placing at least one stimulation electrode in electrical contact with the target muscle and applying an electrical signal to the stimulation electrode. The method further includes obtaining a signal from a sensing element placed on the patient, wherein the sensing element is configured to detect at least one biological parameter of the patient associated with contraction of the target muscle caused by the application of the electrical signal, and adapting stimulation of the target muscle by the at least one stimulation electrode using the obtained signal.

公开(公告)号：US20210084999A1

公开(公告)日：2021-03-25

申请号：US17112434

申请日：2020-12-04

申请人： Tau Orthopedics, Inc.

发明人： Belinko K. Matsuura ,  David G. Matsuura ,  Kaitlin von Hoffmann ,  Gerard von Hoffmann

IPC分类号： A41D13/00 ,  A63B21/008 ,  A63B24/00 ,  A63B23/04 ,  A63B21/00 ,  A61B5/00 ,  G09B19/00 ,  G06Q10/06 ,  G09B23/28 ,  A61N1/36 ,  A61N1/04 ,  A61B5/0492 ,  G16H20/30 ,  G16H40/67 ,  A41D1/00 ,  A63B21/005

摘要： A wearable device such as a garment is disclosed, having at least one sensor, for sensing a parameter. Electronics are provided for processing the sensed parameter, and for providing feedback. Feedback may be in the form of proprioceptive tactile or audible feedback, or in the form of an adjustment of a performance parameter of the wearable device. In one implementation, the processor is configured to activate an effector to provide feedback to the wearer to make a body position correction to bring the position into alignment with predetermined body position reference data.

公开(公告)号：US20210068696A1

公开(公告)日：2021-03-11

申请号：US16642854

申请日：2018-08-30

申请人： San Diego State University Research Foundation

发明人： Samuel K. Kassegne ,  Surabhi Nimbalkar ,  Arvind Balasubramani

IPC分类号： A61B5/0492 ,  A61B5/0478 ,  A61B5/0484 ,  A61N1/04

摘要： A probe device is disclosed that includes one or more insulating layers and a glassy carbon layer. The glassy carbon layer includes one or more channels. Each channel includes a microstructure, which may include an electrode region, interconnect region, and bump pad region. The electrode region may be placed in contact with a human or animal patient or test subject and used to collect or deliver signals in applications such as electrocorticography (ECoG), electromyography (EMG), and neural stimulation. A method of making a probe includes depositing a glassy carbon precursor on a substrate, patterning the precursor using photolithography, pyrolyzing the precursor to allow the formation of glassy carbon, and depositing one or more insulating layers.

公开(公告)号：US10939867B2

公开(公告)日：2021-03-09

申请号：US15914574

申请日：2018-03-07

申请人： Robert S. Bray, Jr.

发明人： Robert S. Bray, Jr.

IPC分类号： A61B5/00 ,  A61B5/0492 ,  A61N1/04 ,  A61N1/36

摘要： A paralysis monitoring system can be utilized during various medical procedures. Generally, the system is used during procedures involving anesthesia, when general paralysis is necessary, e.g., during surgery that requires cutting through or mobilizing muscle tissue. The paralysis monitoring system stimulates a nerve with low voltage signals and can provide for continuous monitoring and recording of the evoked muscle activity throughout and after a procedure. By monitoring a quantitative response of the muscle activity to nerve stimulation, an anesthesiologist may adjust subsequent doses of a paralytic agent to achieve a desired level of paralysis.

公开(公告)号：US20210038773A1

公开(公告)日：2021-02-11

申请号：US16984042

申请日：2020-08-03

申请人： University of Pittsburgh - Of the Commonwealth System of Higher Education

发明人： Xinyan Cui ,  Kevin M. Woeppel

IPC分类号： A61L31/12 ,  A61B5/1486 ,  A61B5/145 ,  A61N1/362 ,  A61N1/05 ,  A61B5/0408 ,  A61B5/0478 ,  A61B5/0492 ,  A61N1/39 ,  A61N1/36 ,  A61L31/16

摘要： Disclosed herein are embodiments of a conductive polymer doped with silica nanoparticles. In several embodiments, a coated electrode comprising a coating of the conductive polymer on a conductive surface of the electrode is provided. In some embodiments, the silica nanoparticles of the conductive polymer are mesoporous and are loaded with a pharmaceutical agent. Methods of using the conductive polymer doped with silica nanoparticles are also provided, including methods of recording or stimulating a bioelectric signal and methods of administering a pharmaceutical agent to a subject.

公开(公告)号：US10912483B2

公开(公告)日：2021-02-09

申请号：US16292955

申请日：2019-03-05

申请人： EDGE SURGICAL, INC.

发明人： Tomas Matusaitis ,  Kenneth Hoos ,  Christopher Wilson ,  Robert F. Rioux ,  Nitin Khanna ,  Frank Phillips ,  Jim A. Youssef ,  Aniruddha Raina ,  Antonio Belton

IPC分类号： A61B17/16 ,  A61B5/00 ,  A61B5/053 ,  A61B5/0492 ,  A61B5/05 ,  A61B90/00 ,  A61B17/00

摘要： The invention is a system and a handheld device for use in open or minimally invasive surgical procedures, such as a bone implant fixation procedure. The handheld device is configured to perform various functions during a bone implant fixation procedure, including performing at least one of: penetration of a bone to form a hole or opening for receipt of a screw; neuromonitoring, in cooperation with a neuromonitoring device, of the hole during, or post-, formation of the hole so as to sense any nearby nerves adjacent to the hole that may be in the path of a screw, or otherwise affected, when a screw is placed within the hole; neurostimulation, in cooperation with a neuromonitoring device, of nerves adjacent to the hole during, or post-, formation of the hole; and measuring of a depth of the hole and providing a digital measurement of the depth to assist the surgeon in selecting the appropriate length of screw.

公开(公告)号：US20200347279A1

公开(公告)日：2020-11-05

申请号：US16936628

申请日：2020-07-23

申请人： DDP SPECIALTY ELECTRONICS MATERIALS US, INC.

发明人： Andreas Lutz ,  Daniel Schneider ,  Jeannine Flueckiger

IPC分类号： C09J163/04 ,  C08G59/40 ,  C08G18/10 ,  C09J163/00 ,  C08G65/333 ,  C08G18/80 ,  A61N1/05 ,  C08G59/68 ,  A61B5/04 ,  C08G18/12 ,  C08G18/48 ,  A61B5/00 ,  C08G18/69 ,  C08G18/67 ,  C08L75/08 ,  C08G18/73 ,  A61B5/0492 ,  C08G18/24 ,  C08G18/32 ,  C08G18/62 ,  C08G18/75

摘要： Epoxy adhesives include a latent curing agent, a reactive toughener having capped isocyanate groups, and certain urea compounds. The toughener is made by chain extending and capping a mixture of isocyanate-terminated prepolymers. The prepolymers include an isocyanate-terminated polyether and an isocyanate-terminated diene polymer. The adhesives have excellent wash-off resistance and excellent ability to adhere to oily substrates.

公开(公告)号：US10808148B2

公开(公告)日：2020-10-20

申请号：US15702253

申请日：2017-09-12

申请人： SHIN-ETSU CHEMICAL CO., LTD.

发明人： Jun Hatakeyama ,  Motoaki Iwabuchi ,  Masaki Ohashi ,  Yasuyoshi Kuroda

IPC分类号： C09J9/02 ,  C07C211/63 ,  A61B5/0408 ,  C07C309/12 ,  C07C219/06 ,  C07C311/48 ,  C07C215/12 ,  C07C217/28 ,  C08G18/75 ,  C08G18/48 ,  C08G18/81 ,  C08F299/06 ,  C08F299/08 ,  C08F290/06 ,  C08G18/61 ,  C09J133/04 ,  C09J175/04 ,  C09J183/04 ,  A61B5/0245 ,  A61B5/053 ,  A61B5/00 ,  C07C309/17 ,  C07C309/19 ,  C07C309/24 ,  C07D211/06 ,  C07J31/00 ,  C09J11/04 ,  C09J11/06 ,  C09J183/08 ,  A61B5/0492 ,  A61B5/0478 ,  C08G77/20 ,  C08G77/12 ,  C08K3/04 ,  C08K5/42

摘要： An adhesive composition including a resin and electro-conductive material, wherein the electro-conductive material is an ammonium salt of fluorosulfonic acid having 5 or more carbon atoms shown by the general formula (1): (R1—X—Z—SO3−)n Mn+ (1), wherein, R1 represents a monovalent hydrocarbon group having 1 to 40 carbon atoms and optionally substituted by a heteroatom or optionally interposed by heteroatom; X represents any of a single bond, ether group, ester group, and amide group; Z represents an alkylene group having 2 to 4 carbon atoms, containing 1 to 6 fluorine atoms, and optionally containing a carbonyl group; Mn+ represents a cation having one or two ammonium cation structures. This can form a living body contact layer for a bio-electrode with excellent electric conductivity, biocompatibility, and light weight, which manufactures at low cost and does not cause large lowering of the electric conductivity even when it is wetted with water or dried.

公开(公告)号：US10799161B2

公开(公告)日：2020-10-13

申请号：US15090141

申请日：2016-04-04

申请人： Technische Universität Berlin

发明人： Alexander von Luehmann ,  Klaus-Robert Mueller

IPC分类号： A61B5/1455 ,  A61B5/00 ,  H04L27/00 ,  A61B5/0478 ,  A61B5/0476 ,  A61B5/0496 ,  A61B5/0492 ,  A61B5/04 ,  A61B5/0408

摘要： Disclosed is a biosignal acquisition device for the acquisition, in particular the concurrent or simultaneous acquisition, of optical and electrical biosignals. The optical and electrical biosignals are both received by an analog front end device for biosignals, with an opto-electric converter for converting the optical biosignals into electrical signals. Also disclosed are a system of a plurality of biosignal acquisition devices and a biosignal acquisition method.

公开(公告)号：US20200315532A1

公开(公告)日：2020-10-08

申请号：US16850979

申请日：2020-04-16

申请人： Cadwell Laboratories, Inc.

发明人： John A. Cadwell

IPC分类号： A61B5/00 ,  A61B34/10 ,  A61B5/0488 ,  A61B5/0492 ,  A61B5/055 ,  A61B6/00 ,  A61B8/08

摘要： An apparatus, system, and method are disclosed for mapping the location of a nerve. The apparatus includes at least one stimulation module, a stimulation detection module, a distance module, and a mapping module. The stimulation module stimulates a nerve with an electrical stimulation current from at least one stimulation electrode. A stimulation detection module detects a muscle reaction resulting from stimulation of the nerve by the at least one stimulation electrode. The distance module uses information from the at least one stimulation electrode and from the stimulation detection module to calculate a distance between the at least one stimulation electrode and the nerve. The mapping module maps a location on the nerve using at least two distances calculated by the distance module and position information of the at least one stimulation electrode for each of the at least two distances calculated.