公开(公告)号：US20240293491A1

公开(公告)日：2024-09-05

申请号：US18410273

申请日：2024-01-11

申请人： Allergan, Inc.

发明人： Peter A. Simmons ,  Joseph G. Vehige

IPC分类号： A61K36/47 ,  A61K9/00 ,  A61K9/107 ,  A61K31/047 ,  A61K31/205 ,  A61K31/341 ,  A61K31/7004 ,  A61K31/717 ,  A61K47/02 ,  A61K47/18 ,  A61K47/26 ,  A61K47/32 ,  A61K47/44

CPC分类号： A61K36/47 ,  A61K9/0048 ,  A61K9/1075 ,  A61K31/047 ,  A61K31/205 ,  A61K31/341 ,  A61K31/7004 ,  A61K31/717 ,  A61K47/02 ,  A61K47/186 ,  A61K47/26 ,  A61K47/32 ,  A61K47/44

摘要： Provided herein are low salt ophthalmic pharmaceutical composition and methods of use thereof, for example, in the treatment of dry eye syndrome.

公开(公告)号：US20240226222A1

公开(公告)日：2024-07-11

申请号：US18496986

申请日：2023-10-30

申请人： YALE UNIVERSITY

发明人： YUNG-CHI CHENG ,  WING LAM ,  ZAOLI JIAMG

IPC分类号： A61K36/82 ,  A23L33/105 ,  A61K36/24 ,  A61K36/28 ,  A61K36/47 ,  A61K36/59 ,  A61K36/708 ,  A61K36/73 ,  A61K36/756 ,  A61K36/886 ,  A61K9/00 ,  A61K45/06

CPC分类号： A61K36/82 ,  A23L33/105 ,  A61K36/24 ,  A61K36/28 ,  A61K36/47 ,  A61K36/59 ,  A61K36/708 ,  A61K36/73 ,  A61K36/756 ,  A61K36/886 ,  A61K9/0014 ,  A61K9/0053 ,  A61K45/06 ,  A61K2236/331 ,  A61K2236/333

摘要： In one embodiment, the present invention is directed to a composition comprising an aqueous or ethanolic extract of at least one herb selected from the group consisting of Aloe barbadensis (F3), Rheum palmatum L. (:B6), Stephania tetrandra(:C4), Phellodendron chinense Schneid. (:D8), Euphorbia humifusa(:S6), Eclipta prostrata (:I2), A. venetum L. (:F1), Portulaca oleracea L. (:F5), and Sanguisorba officinalis L. (:E5), Camellia sinensis var. assamica (Mast.) Kitamura (:PE) and Punica granatum. (:PG), and mixtures thereof. The composition is administered to a patient, in an effective amount, in a method of treating, inhibiting, preventing, reducing the incidence of, ameliorating or resolving a disease state or condition caused in part or exacerbated by hyperactivity of the androgen receptor (AR), by inhibiting the androgen receptor protein. These compositions may also be used inhibit or stabilize hair loss or grow hair in a subject in need.

公开(公告)号：US20240180994A1

公开(公告)日：2024-06-06

申请号：US18549870

申请日：2022-03-09

申请人： WAHI PHARMACEUTICALS INC.

发明人： Michael HAKKY ,  Shahad AL-FARHOOD

IPC分类号： A61K36/86 ,  A61K36/28 ,  A61K36/47 ,  A61K36/60 ,  A61K36/61 ,  A61K36/81 ,  A61K36/84 ,  A61K36/896 ,  A61K36/906 ,  A61P31/14

CPC分类号： A61K36/86 ,  A61K36/28 ,  A61K36/47 ,  A61K36/60 ,  A61K36/61 ,  A61K36/81 ,  A61K36/84 ,  A61K36/896 ,  A61K36/906 ,  A61P31/14

摘要： A composition comprising (a) an extract of a plant belonging to the family Violaceae; (b) an extract of a plant belonging to the family Myrtaceae; and one or more additional plant extracts wherein the plants are selected from the Moraceae Zingiberaceae, Hyoscamus, Asteraceae, Euphorbiaceae, Iridaceae, and/or Valeriana families. The composition is useful for preventing or ameliorating the effects of infection by a coronavirus including SARS-CoV-2.

公开(公告)号：US11883454B2

公开(公告)日：2024-01-30

申请号：US17834654

申请日：2022-06-07

申请人： Nodari Rizun

发明人： Nodari Rizun

IPC分类号： A61K36/47 ,  A61K36/48 ,  A61K31/201 ,  A61K31/202 ,  A61K31/20 ,  A61K31/047 ,  A61K36/835 ,  A61K36/752 ,  A61K36/61 ,  A61K36/185 ,  A61K31/352 ,  A61K36/76

CPC分类号： A61K36/47 ,  A61K31/047 ,  A61K31/20 ,  A61K31/201 ,  A61K31/202 ,  A61K31/352 ,  A61K36/185 ,  A61K36/48 ,  A61K36/61 ,  A61K36/752 ,  A61K36/76 ,  A61K36/835

摘要： Compositions and methods of manufacturing mineral pitch resin compositions comprising at least one of a cannabinoid, a terpene, a terpenoid, an essential oil and a fatty acid are provided. Such mineral pitch resin compositions may be safely consumed orally, topically or otherwise, and have numerous health benefits.

公开(公告)号：US20240009251A1

公开(公告)日：2024-01-11

申请号：US18371087

申请日：2023-09-21

申请人： XOsmar Industries, LLC

发明人： Humberto Ignacio CAMPILLO RONQUILLO

IPC分类号： A61K35/644 ,  A61K36/53 ,  A61K36/63 ,  A61K9/70 ,  A61K36/28 ,  A61K47/10 ,  A61K36/47

CPC分类号： A61K35/644 ,  A61K36/53 ,  A61K36/63 ,  A61K9/7007 ,  A61K36/28 ,  A61K47/10 ,  A61K36/47

摘要： In one embodiment, a composition may include beeswax, Candelilla wax, oregano oil, glycerin, olive oil, arnica plant concentrate, and carbolic acid. In another embodiment, a method for treating an injury to an affected limb may include may include cleaning the affected limb, providing a water-based treatment composition, applying the water-based treatment composition to the affected limb, providing an oil-based treatment composition, and applying the oil-based treatment composition to the affected limb. The method may further include providing a gauze impregnated with a wax-based treatment composition and wrapping the impregnated gauze around the affected limb. The water-based treatment composition may include water, essence of oregano, and carbolic acid. The oil-based treatment composition may include glycerin, arnica plant concentrate, and carbolic acid. The wax-based treatment composition may include beeswax, Candelilla wax, arnica plant concentrate, and carbolic acid.

公开(公告)号：US20230371669A1

公开(公告)日：2023-11-23

申请号：US17196432

申请日：2021-03-09

申请人： Najla Nouri NESHEIWAT

发明人： Najla Nouri NESHEIWAT

IPC分类号： A45D19/00 ,  A61K36/55 ,  A61K36/889 ,  A61K36/47 ,  A61K36/71 ,  A61K36/63 ,  A61K36/185 ,  A61K36/736 ,  A61K36/31 ,  A61K36/8962 ,  A61K36/22 ,  A61K8/92 ,  A61K36/67 ,  A61K36/73 ,  B08B1/00 ,  A61N5/06

CPC分类号： A45D19/005 ,  A61K36/55 ,  A61K36/889 ,  A61K36/47 ,  A61K36/71 ,  A61K36/63 ,  A61K36/185 ,  A61K36/736 ,  A61K36/31 ,  A61K36/8962 ,  A61K36/22 ,  A61K8/922 ,  A61K36/67 ,  A61K36/73 ,  B08B1/002 ,  A61N5/0617 ,  A61K2236/15 ,  A61N2005/0657 ,  A61B2017/320004

摘要： A formula and method to counteract hair loss, where the formula is a mixture. The mixture consists of Flaxseed oil, Coconut oil, Castor oil, Nigella sativa oil, Olive oil, Sesame oil, Sweet Almond oil, Bitter Almond oil, Watercress oil, Jojoba oil, Garlic oil, Onion oil, and Pistacia lentiscus oil. The oils derived from seeds are cold rolled to produce the oil. The mixture is applied to the scalp after brushing and washing of the scalp area to be treated.

公开(公告)号：US11779623B2

公开(公告)日：2023-10-10

申请号：US17834654

申请日：2022-06-07

申请人： Nodari Rizun

发明人： Nodari Rizun

IPC分类号： A61K36/47 ,  A61K36/48 ,  A61K31/201 ,  A61K31/202 ,  A61K31/20 ,  A61K31/047 ,  A61K36/835 ,  A61K36/752 ,  A61K36/61 ,  A61K36/185 ,  A61K31/352 ,  A61K36/76

CPC分类号： A61K36/47 ,  A61K31/047 ,  A61K31/20 ,  A61K31/201 ,  A61K31/202 ,  A61K31/352 ,  A61K36/185 ,  A61K36/48 ,  A61K36/61 ,  A61K36/752 ,  A61K36/76 ,  A61K36/835

摘要： Compositions and methods of manufacturing mineral pitch resin compositions comprising at least one of a cannabinoid, a terpene, a terpenoid, an essential oil and a fatty acid are provided. Such mineral pitch resin compositions may be safely consumed orally, topically or otherwise, and have numerous health benefits.

公开(公告)号：US11779564B2

公开(公告)日：2023-10-10

申请号：US16617466

申请日：2018-05-31

申请人： NAPO PHARMACEUTICALS, INC.

发明人： Lisa A. Conte ,  Pravin R. Chaturvedi ,  Charles Conte

IPC分类号： A61K31/353 ,  A61P1/12 ,  A61K31/451 ,  A61K36/47

CPC分类号： A61K31/353 ,  A61K31/451 ,  A61K36/47 ,  A61P1/12

摘要： Presented herein are methods for treating bile acid diarrhea, short bowel syndrome (SBS), and cholecystectomy-associated diarrhea by administering to a patient in need thereof, an inhibitor of chloride-ion transport in an amount sufficient to treat diarrhea. In particular embodiments, infants, and juveniles with SBS are treated with an inhibitor of chloride-ion transport in an amount sufficient to treat diarrhea. Treatment of diarrhea includes the treatment of the diarrhea as well as the pain, abdominal discomfort and other symptoms associated with diarrhea. In one embodiment, the inhibitor of chloride-ion transport is crofelemer.

公开(公告)号：US20230233637A1

公开(公告)日：2023-07-27

申请号：US18129182

申请日：2023-03-31

申请人： Akrivista LLC

发明人： Scott Whitcup ,  Orest Olejnik ,  Michael Garst ,  Peter Simmons

IPC分类号： A61K36/235 ,  A61P27/04 ,  A61K9/00 ,  A61K36/534 ,  A61K36/61 ,  G01N33/50 ,  A61K36/54 ,  A61K36/752 ,  A61K47/32 ,  A61K9/107 ,  A61K36/47 ,  A61K47/44

CPC分类号： A61K36/235 ,  A61P27/04 ,  A61K9/0048 ,  A61K36/534 ,  A61K36/61 ,  G01N33/50 ,  A61K36/54 ,  A61K36/752 ,  A61K47/32 ,  A61K9/1075 ,  A61K36/47 ,  A61K47/44

摘要： In preferred embodiments the invention is directed to ocular compositions for the treatment of dry eye, methods for making such compositions, and suites comprising a plurality of different ocular compositions each having a defined composition. In preferred examples, the invention is directed to compositions comprising at least one natural oil, wherein a first member of the suite of compositions is effective in treating dry in in a first patient having a particular set of symptoms and a different second member of the suite of compositions is effective in treating dry in in a second patient having a different set of symptoms. The invention is also directed to methods of making and using the compositions, and to skin care compositions for use around the eye, such as the upper and lower eyelids having a lubricating, non-irritating base composition comprising at least one natural oil.

公开(公告)号：US20220110992A1

公开(公告)日：2022-04-14

申请号：US17482369

申请日：2021-09-22

申请人： ALPHYN BIOLOGICS, LLC

发明人： Gary Michael PEKOE ,  Jazmyne Kristyne MINK ,  Steven Aaron PENTELNIK ,  Neal G. KOLLER

IPC分类号： A61K36/47 ,  A61P31/04 ,  A61K31/353 ,  A61K31/352 ,  A61K31/343

摘要： The present disclosure provides for a method of treating a bacterial colonization or primary or secondary bacterial infection of an underlying skin disorder in a subject via the topical administration of a pharmaceutical composition comprising a therapeutically effective amount of an extract of the Croton lechleri tree. Additionally the present disclosure provides for a method of treating a bacterial colonization or primary or secondary bacterial infection of the nasal mucosa in a subject via the nasal administration of a pharmaceutical composition comprising a therapeutically effective amount of an extract of the Croton lechleri tree. Also provided are details of studies on the effectiveness of an extract of the Croton lechleri tree on bacterial pathogens.