公开(公告)号：US12226510B2

公开(公告)日：2025-02-18

申请号：US17680816

申请日：2022-02-25

Applicant: Topix Pharmaceuticals, Inc.

Inventor： Burt R. Shaffer ,  Steven M. Hernandez

IPC: A61K8/67 ,  A61K8/34 ,  A61K8/49 ,  A61K8/58 ,  A61K8/60 ,  A61K8/73 ,  A61K8/891 ,  A61K8/894 ,  A61K9/00 ,  A61K31/07 ,  A61K36/82 ,  A61K47/16 ,  A61K47/34 ,  A61P17/02 ,  A61P17/06 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08

Abstract: Disclosed are stable, non-irritating, retinoid containing formulations and delivery systems for topical application to the skin. The disclosed topical formulations and delivery systems provide controlled release of the retinoid to the skin for the treatment of amenable skin conditions as well as for improvement of aesthetic skin properties. Also provided are methods for the formulation, manufacture and use of the disclosed retinoid containing formulations and delivery systems.

公开(公告)号：US12178837B2

公开(公告)日：2024-12-31

申请号：US18520281

申请日：2023-11-27

Applicant: AMOREPACIFIC CORPORATION

Inventor： Juewon Kim ,  Si Young Cho ,  Hyungsu Kim ,  Wonseok Park ,  Joonho Choi ,  Dong Hyun Kim ,  Jaewon You ,  Miyoung Park

IPC: A61K36/82 ,  A23L33/105 ,  A61K8/97 ,  A61Q19/02 ,  A61Q19/08

Abstract: Disclosed is to provide a composition for skin-whitening or preventing or improving skin wrinkles, comprising a green tea extract which has modified amounts of ingredients. More specifically, the extract and composition according to one aspect of the present disclosure are derived from natural plants that cause less irritation to the skin and are eco-friendly, thus they are safe, and thereby the extract and composition can exhibit excellent effects of effectively inhibiting melanin production and tyrosinase activity and preventing or improving skin whitening, and can exhibit excellent effects of effectively inhibiting the expression of MMP-1 and preventing or improving skin wrinkles.

公开(公告)号：US20240415767A1

公开(公告)日：2024-12-19

申请号：US18742931

申请日：2024-06-13

Applicant: Brent Paul Spicer

Inventor： Brent Paul Spicer

IPC: A61K9/06 ,  A61K31/047 ,  A61K31/12 ,  A61K31/355 ,  A61K31/4166 ,  A61K35/644 ,  A61K36/185 ,  A61K36/355 ,  A61K36/489 ,  A61K36/53 ,  A61K36/534 ,  A61K36/537 ,  A61K36/82 ,  A61K36/886 ,  A61K36/889 ,  A61K47/32 ,  A61P17/02

Abstract: The present invention relates to compositions or formulations or systems for aftercare of a recently-created tattoo on a skin, that includes a tattoo aftercare sealant gel. The tattoo aftercare sealant gel comprises gel-forming-and-bonding components, and natural ingredients for healing to alleviate the risk of wounding or scarring or infection or drying of the skin or irritating the skin, and to keep the tattoo from fading or drying out. Further, the present invention also discloses methods of production of the compositions or formulations, or systems for aftercare of a recently-created tattoo on a skin as disclosed herein, and it creates a tattoo aftercare sealant gel of the present invention. Also, the present invention provides methods of treatment and/or prevention of wounds, injury, infection and/or disease of tattooed skin, for aftercare of a recently-created tattoo on a skin, involving the use of the tattoo aftercare sealant gel of the present invention.

公开(公告)号：US20240398857A1

公开(公告)日：2024-12-05

申请号：US18677013

申请日：2024-05-29

Applicant: PAPILLEX INC.

Inventor： Elizabeth GOLDSPINK

IPC: A61K33/30 ,  A61K31/07 ,  A61K31/353 ,  A61K31/375 ,  A61K31/519 ,  A61K31/714 ,  A61K33/04 ,  A61K36/074 ,  A61K36/31 ,  A61K36/481 ,  A61K36/82 ,  A61K45/06 ,  A61P31/20

Abstract: A composition for the management of Human Papillomavirus (HPV) infections is provided. The composition comprises a combination of activated folate, one or more zinc compounds such as zinc sulfate, a phenol catechin such as Epigallocatechin-3-gallate (EGCG), broccoli seed or sprout, and one or more carotenoids. The composition may comprise one or more mushrooms or mushroom extracts. The composition may be useful for the control of symptoms associated with HPV infection in one or more individuals, and may also include reducing the frequency and/or persistence of HPV related conditions.

公开(公告)号：US20240374669A1

公开(公告)日：2024-11-14

申请号：US18664854

申请日：2024-05-15

Applicant: MARY KAY INC.

Inventor： Tiffany CARLE

IPC: A61K36/87 ,  A61K8/49 ,  A61K8/97 ,  A61K8/9789 ,  A61K9/00 ,  A61K9/107 ,  A61K31/05 ,  A61K31/353 ,  A61K31/56 ,  A61K31/704 ,  A61K36/23 ,  A61K36/575 ,  A61K36/82 ,  A61Q19/00 ,  A61Q19/08

Abstract: A method of treating telangiectasia in a subject in need thereof is disclosed. The method includes topically applying to skin of said subject in need of treatment of telangiectasia a composition comprising effective amounts of an extract of Centella asiactica leaf and an extract of Vitis vinifera seed to disrupt endothelia tubes in skin.

公开(公告)号：US20240277789A1

公开(公告)日：2024-08-22

申请号：US18633805

申请日：2024-04-12

Applicant: CODEX LABS CORPORATION

Inventor： Jessica MALOH ,  Barbara A. PALDUS ,  Raja SIVAMANI

IPC: A61K35/747 ,  A61K9/00 ,  A61K31/353 ,  A61K31/57 ,  A61K35/00 ,  A61K35/742 ,  A61K35/745 ,  A61K36/328 ,  A61K36/82 ,  A61K45/06 ,  A61P17/10

CPC classification number: A61K35/747 ,  A61K9/0053 ,  A61K31/353 ,  A61K31/57 ,  A61K35/742 ,  A61K35/745 ,  A61K36/328 ,  A61K36/82 ,  A61K45/06 ,  A61P17/10 ,  A61K2035/115

Abstract: The present disclosure relates to compositions and methods useful for dietary augmentation to provide therapeutic intervention for the treatment and management of acne-prone skin. According to one embodiment of the present disclosure, there is provided an orally administrable composition containing a therapeutically effective amount of: (a) a probiotic blend of bacterial components containing at least: (i) Lactobacillus acidophilus, (ii) Bifidobacterium lactis, an (iii) Bacillus coagulans; (b) guggul; and (c) green tea leaf.

公开(公告)号：US20240261361A1

公开(公告)日：2024-08-08

申请号：US18639128

申请日：2024-04-18

Applicant: OCuSOFT, Inc.

Inventor： Nat Adkins, JR. ,  Paramita Sarkar ,  Troy Smith

IPC: A61K36/82 ,  A61K36/61 ,  A61K47/10 ,  A61K47/18 ,  A61K47/26

CPC classification number: A61K36/82 ,  A61K36/61 ,  A61K47/10 ,  A61K47/18 ,  A61K47/26

Abstract: An anti-allergenic product having: at least 0.01% w/w of a plant extract, wherein the plant extract is selected from the group consisting of Camellia sinensis leaf extract, Melaleuca alternifolia leaf oil, and mixtures thereof; an amphiphilic preservative, and a glycolipid. The eyelid cleansing composition is configured to relieve redness, discomfort and irritation in and around the eyelid.

公开(公告)号：US20240226223A1

公开(公告)日：2024-07-11

申请号：US18536404

申请日：2023-12-12

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyun Woo JEONG ,  Jinoh CHUNG ,  Wanki KIM ,  Jong Hwa ROH

IPC: A61K36/82 ,  A61K38/16 ,  A61P21/00

CPC classification number: A61K36/82 ,  A61K38/168 ,  A61P21/00 ,  A61K2236/19 ,  A61K2236/331 ,  A61K2236/333

Abstract: The present disclosure relates to a composition for preventing, improving, or treating muscle loss comprising a green tea peptide composition. Specifically, the green tea peptide composition according to the present disclosure may exhibit an efficacy in preventing, improving, or treating muscle loss through the excellent effects of increasing protein synthesis in muscle cells and inhibiting protein degradation in the muscle cells, and thus may be applied in various health functional food compositions and pharmaceutical compositions.

公开(公告)号：US11969405B2

公开(公告)日：2024-04-30

申请号：US17901688

申请日：2022-09-01

Applicant: DERMA RESEARCH GROUP INC.

Inventor： Dusan Sajic ,  Maksym Breslavets ,  Scottpatrick Sellitto

IPC: A61K31/327 ,  A61K9/00 ,  A61K9/06 ,  A61K31/045 ,  A61K31/05 ,  A61K31/095 ,  A61K31/145 ,  A61K31/194 ,  A61K31/25 ,  A61K31/455 ,  A61K31/65 ,  A61K31/7048 ,  A61K31/7056 ,  A61K33/30 ,  A61K36/185 ,  A61K36/58 ,  A61K36/61 ,  A61K36/74 ,  A61K36/82 ,  A61K47/34 ,  A61P17/10

CPC classification number: A61K31/327 ,  A61K9/0014 ,  A61K9/06 ,  A61K31/045 ,  A61K31/05 ,  A61K31/095 ,  A61K31/145 ,  A61K31/194 ,  A61K31/25 ,  A61K31/455 ,  A61K31/65 ,  A61K31/7048 ,  A61K31/7056 ,  A61K33/30 ,  A61K36/185 ,  A61K36/58 ,  A61K36/61 ,  A61K36/74 ,  A61K36/82 ,  A61K47/34 ,  A61P17/10

Abstract: In some aspects, the techniques described herein relate to a topical dermatologic acne treatment method using a cream. The treatment method uses two steps, first providing a bactericidal component and second providing a skin revitalizing complex. The bactericidal component clears the acne causing bacteria. The subsequent skin revitalizing complex revitalizes and conditions the skin and aids in return of natural skin flora and microbiome to prevent subsequent outbreaks. The skin revitalizing complex can include a variety of components such as: niacinamide, retinol, bakuchiol, green coffee bean extract, green tea extract, epilobium fleischeri extract, citric acid, dimethicone, and pentaerythrityl tetracaprylate. The skin revitalizing complex restores natural elasticity and oil production of the skin, decrease sebum production, and provide necessary conditioning of the skin to provide for the natural skin flora and microbiome to repopulate and flourish on a surface of the skin.

公开(公告)号：US11957727B2

公开(公告)日：2024-04-16

申请号：US17395249

申请日：2021-08-05

Applicant: Therapeutic Solutions International, Inc.

Inventor： Thomas E. Ichim ,  Famela Ramos ,  James Veltmeyer ,  Timothy G. Dixon

IPC: A61K36/82 ,  A61K31/09 ,  A61K31/122 ,  A61K31/26 ,  A61K31/353 ,  A61K36/31 ,  A61K36/45 ,  A61K36/71 ,  A61P25/28

CPC classification number: A61K36/82 ,  A61K31/09 ,  A61K31/122 ,  A61K31/26 ,  A61K31/353 ,  A61K36/31 ,  A61K36/45 ,  A61K36/71 ,  A61P25/28

Abstract: Disclosed are means, methods, and therapeutic compositions for prevention of memory loss during situations of neuroinflammation. In one embodiment the invention teaches administration of the therapeutic combination of ingredients comprising of pterostilbene, Nigella sativa, sulforaphane, and epigallocatechin-3-gallate (EGCG) to a mammal suffering from inflammation in order to preserver memory function.