公开(公告)号：US20250064702A1

公开(公告)日：2025-02-27

申请号：US18711955

申请日：2022-12-08

Applicant: SHISEIDO COMPANY, LTD.

Inventor： Seiji NISHIKAWA ,  Ikuhiro SUZUKI ,  Yusuke OKUYAMA

IPC: A61K8/49 ,  A61K8/06 ,  A61K8/36 ,  A61Q19/08

Abstract: [Problem] To provide an oil-in-water emulsion cosmetic having an excellent feel in use.
[Solution] An oil-in-water emulsion cosmetic comprising (A) a cyclic carboxamide derivative having a specific structure or its salt, (B) a straight-chain higher fatty acid having 16 or more carbon atoms, (C) a higher alcohol, (D) a nonionic surfactant, (E) an oil, and (F) water.

公开(公告)号：US20250064701A1

公开(公告)日：2025-02-27

申请号：US18941754

申请日：2024-11-08

Applicant: UNIVERSIDAD DE GRANADA

Inventor： Germaine ESCAMES ROSA ,  Darío ACUÑA CASTROVIEJO ,  Luis Carlos LÓPEZ GARCIA

IPC: A61K8/49 ,  A61K8/35 ,  A61K9/00 ,  A61K31/122 ,  A61K31/4045 ,  A61Q17/04 ,  A61Q19/08

Abstract: The invention relates to a composition comprising melatonin, a metabolite or derivative thereof and coenzyme Q10 and to use thereof for the production of a pharmaceutical or cosmetic composition for the treatment of the skin, said composition potentiating the movement of both molecules into the mitochondrion and facilitating percutaneous absorption, in which both the melatonin and the CoQ10 can reach all of the strata of the skin.

公开(公告)号：US12233145B2

公开(公告)日：2025-02-25

申请号：US17297351

申请日：2020-01-02

Applicant: CIIMAR—CENTRO DE INVESTIGACAO MARINHA E AMBIENTAL ,  UNIVERSIDADE DO PORTO ,  FACULTY OF SCIENCES, CHOUAIB DOUKKALI UNIVERSITY

Inventor： Teresa Patricia Pedrosa Martins ,  Mariana Alves Reis ,  Pedro Nuno Da Costa Leao ,  Vitor Manuel Oliveira Vasconcelos ,  Meryem Hassouani ,  Brahim Sabour

IPC: A61K8/49 ,  A61Q17/00 ,  A61Q17/04 ,  G02B1/04 ,  G02B5/00 ,  G02C7/10

Abstract: Novel compounds able to absorb UV radiation and comprise antimicrobial properties as well. The compounds are novel and undisclosed scytonemin analogs, able to absorb up to 90% of UV-A radiation and can cover a broader UV to blue light absorption range from 293 nm to 500 nm. When mixtures of more than one compound are used, their synergetic absorption properties can cover an even broader spectrum within 293 nm to 500 nm. The compounds present faint coloration, and some are even colorless, therefor the present compounds can be easily incorporated in formulations to be used in cosmetic products, sunscreens or lenses for sunglasses.

公开(公告)号：US12226513B2

公开(公告)日：2025-02-18

申请号：US17852525

申请日：2022-06-29

Applicant: L'OREAL

Inventor： Jonathan Faig ,  Nicole Burkhard ,  David Chan ,  Susan Halpern Chirch

IPC: A61K8/44 ,  A61K8/04 ,  A61K8/34 ,  A61K8/368 ,  A61K8/49 ,  A61K8/73 ,  A61K8/81 ,  A61Q19/00

Abstract: The instant disclosure relates to a rheological-modifying and stabilizing polymer blend, cosmetic compositions comprising the polymer blend, and methods for stabilizing, for modifying viscosity, and for treating the skin using the polymer blend or using cosmetic compositions comprising the polymer blend. The rheological-modifying and stabilizing polymer blend comprises: (i) a carbomer; (ii) acrylates/C10-30 alkyl acrylate crosspolymer; and (iii) ammonium acryloyldimethyltaurate/steareth-25 methacrylate crosspolymer.

公开(公告)号：US12226508B2

公开(公告)日：2025-02-18

申请号：US17735969

申请日：2022-05-03

Applicant: Dalhousie University

Inventor： Alec Guy Falkenham

IPC: A61K8/55 ,  A61K8/14 ,  A61K8/49 ,  A61Q1/14

Abstract: The present invention provides a method for removing a tattoo in a region of skin the method comprises administering to a least a portion of the tattoo a composition comprising an effective amount of a bisphosphonate and at least one pharmaceutically acceptable excipient to at least cause fading of the tattoo in said region.

公开(公告)号：US20250049683A1

公开(公告)日：2025-02-13

申请号：US18591891

申请日：2024-02-29

Applicant: Elise A. Olsen

Inventor： Mitchell A. deLong ,  Elise A. Olsen

IPC: A61K8/64 ,  A61K8/37 ,  A61K8/49 ,  A61K8/69 ,  A61K31/198 ,  A61K31/215 ,  A61K31/4439 ,  A61K31/585 ,  A61K31/7004 ,  A61K45/06 ,  A61Q5/02 ,  A61Q5/08 ,  A61Q7/00 ,  A61Q7/02 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/10

Abstract: A method for inhibiting hair growth in mammals using compositions containing FP receptor antagonists (e.g., prostaglandin F analogs that are block activation of the FP receptor). The compositions can be applied topically to the skin and/or hair. The compositions can arrest hirsutism or hypertrichosis, reverse hirsutism and hypertrichosis, and further prevent hair growth. These compositions can also be used to protect hair from chemical or radiation-induced alopecia or hair loss. These compositions can also be used to inhibit pigmentation of the hair or skin.

公开(公告)号：US20250041191A1

公开(公告)日：2025-02-06

申请号：US18793411

申请日：2024-08-02

Applicant: RoC OPCO LLC

Inventor： Arthur Pellegrino ,  Michelle Taylor

IPC: A61K8/49 ,  A61K8/34 ,  A61K8/44 ,  A61K8/67 ,  A61K8/9789 ,  A61Q19/02

Abstract: Disclosed herein are compositions for evening skin tone comprising at least one tyrosine formation inhibitor, at least one tyrosinase inhibitor, and at least one agent that reduces melanosome transfer from melanocytes to keratinocytes, wherein the composition does not comprise hydroquinone. Disclosed uses of the compositions include methods for persistently evening skin tone.

公开(公告)号：US20250041189A1

公开(公告)日：2025-02-06

申请号：US18706991

申请日：2022-11-18

Applicant: SHISEIDO COMPANY, LTD.

Inventor： Shunsuke IRIYAMA

IPC: A61K8/49 ,  A61K8/9711 ,  A61K8/9717 ,  A61K8/9722 ,  A61Q19/08

Abstract: The present disclosure relates to providing a substance and a composition that promote the proliferation of epidermal stem cells and are effective in improving wrinkles and barrier function from the viewpoint of maintaining or improving quality of life (QOL) in terms of both health and beauty. More specifically, a composition including 1-(2-hydroxyethyl)-2-imidazolidinone (HEI) or a derivative thereof and a seaweed extract such as Marinwort IPC-12 AGS can be used to promote the proliferation of epidermal stem cells and obtain a beneficial effect on wrinkles and barrier function.

公开(公告)号：US20250041178A1

公开(公告)日：2025-02-06

申请号：US18364556

申请日：2023-08-03

Applicant: L'OREAL

Inventor： Florence BARRAQUET

IPC: A61K8/368 ,  A61K8/365 ,  A61K8/49 ,  A61Q19/08

Abstract: The present invention relates to compositions including water, monoalcohol, alpha hydroxy acid, beta hydroxy acid, and polyhydroxy acid, and optionally humectant, as well as to methods of using and making such compositions.

公开(公告)号：US20250032457A1

公开(公告)日：2025-01-30

申请号：US18838889

申请日：2021-09-14

Applicant: Eric Rauch

Inventor： Eric Rauch

IPC: A61K31/4174 ,  A61K8/49 ,  A61K31/4164 ,  A61K31/506 ,  A61K31/56 ,  A61P17/14 ,  A61Q7/00 ,  A61Q19/08

Abstract: Described herein are methods of using one or more azole compounds in treating androgenic alopecia, reducing or stopping hair thinning, reversing hair thinning, promoting hair growth, reversing hairline recession, and/or treating a skin condition.