公开(公告)号：US10525158B2

公开(公告)日：2020-01-07

申请号：US15300301

申请日：2015-03-23

申请人： Novartis AG

发明人： Robert Carey Tucker

IPC分类号： A61L12/10 ,  A61L12/08 ,  A61L12/00 ,  C02F1/467 ,  A61L12/02 ,  A61L12/14 ,  C11D3/00

摘要： The present invention is generally related to a lens care system and method for disinfecting and cleaning contact lenses. A lens care system or method of the invention is based on electrolysis of an aqueous chloride solution for generating germicide species (e.g., chlorine, hypochlorous acid, hypochlorite, or combinations thereof) and subsequent in-situ electrolysis of hypochlorous acid or hypochlorite in the aqueous solution for neutralizing the generated germicide species.

公开(公告)号：US20190381205A1

公开(公告)日：2019-12-19

申请号：US16518675

申请日：2019-07-22

申请人： Novartis AG

发明人： Robert Carey Tucker

IPC分类号： A61L12/12 ,  B08B3/08 ,  C02F1/461 ,  C02F1/66 ,  A61L12/02 ,  A61L12/10 ,  C11D3/00 ,  C11D3/39 ,  C11D11/00

摘要： The present invention is generally directed to a hydrogen peroxide-based lens care system for disinfecting contact lenses. Unlike hydrogen peroxide-based system known in the prior art, a lens care system of the present invention involves electrochemically neutralizing of hydrogen peroxide after any desired period of disinfection time for which contact lenses have been immersed in a hydrogen peroxide-based lens care solution.

公开(公告)号：US10010081B2

公开(公告)日：2018-07-03

申请号：US15454859

申请日：2017-03-09

申请人： S.K. PHARMACEUTICALS, INC.

发明人： Hampar L. Karageozian

IPC分类号： A61K31/728 ,  A61K33/20 ,  A61K33/40 ,  A61K33/22 ,  A61K9/00 ,  A61L12/10 ,  A01N59/00 ,  A61L12/12 ,  A61K33/00 ,  A61K33/14

CPC分类号： A01N59/00 ,  A61K9/0014 ,  A61K9/0048 ,  A61K31/728 ,  A61K33/00 ,  A61K33/14 ,  A61K33/20 ,  A61K33/22 ,  A61K33/40 ,  A61L12/10 ,  A61L12/124 ,  A61K2300/00

摘要： An anti-microbial preservative for use in ophthalmic and dermatologic products. The preservative includes from about 0.005 wt. % to about 0.20 wt. % chlorite compound and from about 0.005 wt. % to about 0.05 wt. % peroxy compound. Additionally, the preservative does not generate chlorine dioxide within the pH range of 5.0-8.8. Also included are an antimicrobial ophthalmic and dermatologic compositions for direct application onto an eye or skin of a living being including from about 0.005 wt. % to about 0.20 wt. % chlorite compound and from about 0.005 wt. % to about 0.05 wt. % peroxy compound. Also included are methods for treating dryness of the eyes and skin disorders (e.g., wounds, burns, infections, ulcerations, psoriasis, etc.) and for disinfecting and cleansing contact lenses while in place upon an eye by applying the composition to the eye or to the contact lens.

公开(公告)号：US20170173206A1

公开(公告)日：2017-06-22

申请号：US15300301

申请日：2015-03-23

申请人： Novartis AG

发明人： Robert Carey Tucker

IPC分类号： A61L12/00 ,  C11D3/00 ,  A61L12/10 ,  A61L12/14 ,  A61L12/02 ,  A61L12/08

CPC分类号： A61L12/00 ,  A61L12/023 ,  A61L12/08 ,  A61L12/086 ,  A61L12/10 ,  A61L12/14 ,  C02F1/4674 ,  C11D3/0078

摘要： The present invention is generally related to a lens care system and method for disinfecting and cleaning contact lenses. A lens care system or method of the invention is based on electrolysis of an aqueous chloride solution for generating germicide species (e.g., chlorine, hypochlorous acid, hypochlorite, or combinations thereof) and subsequent in-situ electrolysis of hypochlorous acid or hypochlorite in the aqueous solution for neutralizing the generated germicide species.

公开(公告)号：US20170065738A1

公开(公告)日：2017-03-09

申请号：US15256299

申请日：2016-09-02

申请人： The Administrators of the Tulane Educational Fund

发明人： Chad ROY ,  Rebecca METZINGER ,  Robert REIMERS

IPC分类号： A61L12/10 ,  A61L12/14 ,  A61L2/18

CPC分类号： A61L12/10 ,  A61L2/0088 ,  A61L2/18 ,  A61L12/102 ,  A61L12/142 ,  A61L12/143 ,  A61L12/145 ,  A61L2202/24

摘要： The present disclosure discloses compositions and methods for multipurpose disinfection and sterilization solutions broadly effective against multiple microbial pathogens. The present disclosure demonstrates broad spectrum antimicrobial activity against environmental and pathogenic amoeba, bacterial spores, vegetative bacteria, fungi, rickettsia, viruses, parasites and toxic microbial products. The multipurpose disinfection solutions of the present disclosure may be used alone or in combination for a variety of purposes, including disinfection of medical devices such as contact lenses, contact lens cases, surgical instruments, and dental instruments.

摘要翻译： 本公开公开了用于对多种微生物病原体广泛有效的多用途消毒和杀菌溶液的组合物和方法。 本公开内容展示针对环境和致病性变形虫，细菌孢子，营养细菌，真菌，立克次体，病毒，寄生虫和有毒微生物产物的广谱抗微生物活性。 本公开的多功能消毒溶液可以单独使用或组合使用，用于各种目的，包括消毒医疗器械如隐形眼镜，隐形眼镜盒，手术器械和牙科器械。

公开(公告)号：US06916446B1

公开(公告)日：2005-07-12

申请号：US10251697

申请日：2002-09-18

申请人： Laurence G. Miller ,  Ronald S. Oremland ,  Shaun M. Baesman

发明人： Laurence G. Miller ,  Ronald S. Oremland ,  Shaun M. Baesman

IPC分类号： A61L2/20 ,  B01D15/00 ,  B01J20/20 ,  C12P3/00 ,  A61L9/00 ,  A61L12/10 ,  B01D15/08 ,  C12P1/04 ,  G01D21/02

CPC分类号： C12P3/00 ,  A61L2/20 ,  B01D15/00 ,  B01J20/20

摘要： Methyl halide contaminants are oxidized in a reaction chamber containing a methylotrophic bacterium through direct oxidation of the methyl halide contaminant. Methyl halides may be used as a disinfectant, with the remnant methyl halide contaminant oxidized through direct oxidation by the methylotrophic bacterium.

摘要翻译： 甲基卤污染物通过甲基卤污染物的直接氧化在含有甲基营养细菌的反应室中被氧化。 甲基卤可以用作消毒剂，残留的甲基卤污染物被甲基营养细菌直接氧化而氧化。

公开(公告)号：US5330752A

公开(公告)日：1994-07-19

申请号：US125088

申请日：1993-09-21

申请人： John Y. Park ,  James N. Cook

发明人： John Y. Park ,  James N. Cook

IPC分类号： A61L12/10 ,  A61L12/12 ,  C11D3/00 ,  C11D3/38 ,  C11D3/386 ,  C11D3/39 ,  C11D3/395 ,  A61K37/50 ,  A61K33/40 ,  A61L9/00 ,  C11D3/48

CPC分类号： C11D3/38654 ,  A61L12/102 ,  A61L12/124 ,  C11D3/0078 ,  C11D3/38 ,  C11D3/3947 ,  C11D3/3956 ,  Y10S514/839 ,  Y10S514/84

摘要： Compositions and methods useful in destroying residual oxidative disinfectant, e.g., used to disinfect a contact lens, are disclosed. In one embodiment, the method comprises contacting an oxidative disinfectant-containing liquid medium with a material selected from glutathione, oxidized glutathione and mixtures thereof, and a co-factor selected from nicotinamide adenine dinucleotide phosphate, nicotinamide adenine dinucleotide and mixtures thereof in the presence of glutathione reductase in an amount effective to promote the oxidation of the co-factor.

公开(公告)号：US5320806A

公开(公告)日：1994-06-14

申请号：US888356

申请日：1992-05-22

申请人： Anthony J. Dziabo ,  Paul S. Ripley

发明人： Anthony J. Dziabo ,  Paul S. Ripley

IPC分类号： A61L12/10 ,  C11D3/00 ,  C11D3/34 ,  A61L2/02 ,  C25B1/26

CPC分类号： A61L12/102 ,  C11D3/0078 ,  C11D3/3427 ,  Y10S134/901 ,  Y10S204/06

摘要： A method of disinfecting a contact lens is disclosed and comprises placing the contact lens to be disinfected into a liquid electrolyte containing chlorine dioxide precursor, e.g., stabilized chlorine dioxide, and forming a disinfecting amount of chlorine dioxide in the liquid electrolyte by passing an electric current through the liquid electrolyte.

摘要翻译： 公开了消毒隐形眼镜的方法，包括将要消毒的隐形眼镜放置在含有二氧化氯前体（例如稳定的二氧化氯）的液体电解质中，并通过使电流通过电解液形成消毒量的二氧化氯 通过液体电解液。

公开(公告)号：US5270002A

公开(公告)日：1993-12-14

申请号：US972195

申请日：1992-11-05

申请人： John E. Neff, II ,  Daniel F. Smith

发明人： John E. Neff, II ,  Daniel F. Smith

IPC分类号： A45C11/00 ,  A61L12/10 ,  A61L12/12 ,  A61L2/00

CPC分类号： A45C11/005 ,  A61L12/102 ,  A61L12/128 ,  Y10S134/901

摘要： An apparatus and method for disinfecting a contact lens comprise a container having an inner surface and being sized to hold a contact lens to be disinfected and a liquid medium containing hydrogen peroxide; a substrate located in the container; and a metal component deposited from a vapor medium on the substrate. The metal component is present in an amount effective to promote the decomposition of hydrogen peroxide in the container.

摘要翻译： 用于消毒隐形眼镜的设备和方法包括具有内表面并且尺寸适于保持待消毒的隐形眼镜的容器和含有过氧化氢的液体介质; 位于容器中的基板; 以及从基板上的蒸气介质沉积的金属成分。 金属组分以有效促进容器中过氧化氢分解的量存在。

公开(公告)号：US4886657A

公开(公告)日：1989-12-12

申请号：US278721

申请日：1988-12-02

申请人： Perry A. Ratcliff

发明人： Perry A. Ratcliff

IPC分类号： A01N59/00 ,  A61K8/19 ,  A61K8/22 ,  A61K33/20 ,  A61L12/10 ,  A61Q11/00 ,  A61Q11/02 ,  C11D3/00 ,  C11D7/02

CPC分类号： C11D7/02 ,  A01N59/00 ,  A61K33/20 ,  A61K8/19 ,  A61K8/22 ,  A61L12/102 ,  A61Q11/00 ,  A61Q11/02 ,  C11D3/0078

摘要： The use of stabilized chlorine dioxide or chlorine dioxide in aqueous solution as a composition to reduce or prevent plaque formation and treatment of oral diseases ecologically plaque dependent, such as gingivitis and periodontitis, is disclosed. Preferred concentrations are in the range of 0.005% to 0.2% and the chlorine dioxide may be in the form of a rinse, a wash, a soak or a dentrifice.

摘要翻译： 公开了在水溶液中使用稳定的二氧化氯或二氧化氯作为组合物以减少或预防斑块形成和治疗生态上斑块依赖性的口腔疾病，例如牙龈炎和牙周炎。 优选的浓度在0.005％至0.2％的范围内，并且二氧化氯可以是冲洗，洗涤，浸泡或擦伤的形式。